Gene Group: HEXOSYLTRANSFERASES

General Information

Name

HEXOSYLTRANSFERASES

Species

D. melanogaster

Symbol

HEXT

FlyBase ID

FBgg0001288

Date last reviewed

2019-12-19

Number of members

117

Description

Hexosyltransferases catalyze the transfer of a hexosyl group from donor compound to another acceptor.

Notes on Group

Source Material

The HEXOSYLTRANSFERASES Gene Group has been compiled using the following publication(s): Eisenhaber et al., 2021, Feller et al., 2021, Li et al., 2020, Walski et al., 2017, Yamamoto-Hino et al., 2015, Satoh et al., 2013, Tran et al., 2012, Lin et al., 2008, Chen et al., 2007, Rendic et al., 2006, Tian and Ten Hagen, 2006, Haines and Irvine, 2005, Müller et al., 2005, Mucha et al., 2004, Eisenhaber et al., 2003, Kim et al., 2003, Ten Hagen et al., 2003, Gagou et al., 2002, Roos et al., 2002, and Schwientek et al., 2002 .

Key Gene Ontology (GO) terms

Molecular Function

hexosyltransferase activity

Biological Process

Cellular Component

Enzymatic activity

Enzyme name (EC)

2.4.1.-

Related Gene Groups

Parent group(s)

GLYCOSYLTRANSFERASES

Component group(s)

FUCOSYLTRANSFERASES

GALACTOSYLTRANSFERASES

GLUCOSYLTRANSFERASES

GLUCURONOSYLTRANSFERASES

MANNOSYLTRANSFERASES

N-ACETYLGALACTOSAMINYLTRANSFERASES

N-ACETYLGLUCOSAMINYLTRANSFERASES

OLIGOSACCHARYLTRANSFERASES

UNCLASSIFIED HEXOSYLTRANSFERASES

Members (117)

For all members:

GO ribbon stack

	molecular function	biological process	cellular component

ALPHA 1,3-FUCOSYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

FucTA

alpha1,3-fucosyltransferase A

α1,3-fucosyltransferase, core α1,3-fucosyltransferase

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Rendic et al., 2006, Roos et al., 2002)

FucTB

alpha1,3-fucosyltransferase B

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Rendic et al., 2006, Roos et al., 2002)

FucTC

alpha1,3-fucosyltransferase C

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Rendic et al., 2006, Roos et al., 2002)

FucTD

alpha1,3-fucosyltransferase D

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Rendic et al., 2006, Roos et al., 2002)

ALPHA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

α4GT1

α1,4-galactosyltransferase 1

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Chen et al., 2007, Mucha et al., 2004)

α4GT2

α1,4-galactosyltransferase 2

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Chen et al., 2007, Mucha et al., 2004)

ALPHA 1,6-FUCOSYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

FucT6

α1,6-fucosyltransferase

Fuc-TVIII

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Roos et al., 2002)

BETA 1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

brn

brainiac

l(1)6P6, fs(1)107, fs(1)A107

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

fng

fringe

l(3)rG554

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

β4GalNAcTA

β1,4-N-acetylgalactosaminyltransferase A

b4GalNAcTA, BcDNA:GH13356

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Chen et al., 2007, Haines and Irvine, 2005)

β4GalNAcTB

β1,4-N-acetylgalactosaminyltransferase B

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Chen et al., 2007, Haines and Irvine, 2005)

BETA-N-ACETYLGLUCOSAMINE BETA-1,3-GALACTOSYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

CG3038

EG:BACR37P7.1

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

CG8668

Resille

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

CG8673

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

CG11357

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

CG30036

(FlyBase, 2017-)

CG30037

(FlyBase, 2017-)

GalT1

β1,3-galactosyltransferase 1

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

CHITIN SYNTHASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

Chs2

Chitin synthase 2

CS-2

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Gagou et al., 2002)

kkv

krotzkopf verkehrt

DmCS-1, CS-1, blimp, l(3)82Fh, chitin synthase

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Gagou et al., 2002)

CHONDROITIN SYNTHASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

Chpf

Chondroitin polymerizing factor

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

Chsy

Chondroitin sulfate synthase

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

Csgalnact

Chondroitin sulfate N-acetylgalactosaminyltransferase

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

CORE 1 BETA 1,3-GALACTOSYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

C1GalTA

Core 1 Galactosyltransferase A

dC1GalT1, C1GalT1, core 1 β1,3-galactosyltransferase

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Lin et al., 2008, Müller et al., 2005)

CG2975

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Lin et al., 2008, Müller et al., 2005)

CG2983

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Lin et al., 2008)

CG3119

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Lin et al., 2008)

CG8708

dC1GalT2

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Lin et al., 2008, Müller et al., 2005)

CG18558

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Lin et al., 2008)

CG34056

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Lin et al., 2008, Müller et al., 2005)

CG34057

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Lin et al., 2008, Müller et al., 2005)

CG34451

(FlyBase, 2017-)

CG34452

(FlyBase, 2017-)

tgy

twiggy

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Lin et al., 2008)

DOLICHYL PHOSPHATE N-ACETYLGLUCOSAMINYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

Alg13

Alg13 UDP-N-acetylglucosaminyltransferase subunit

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

DOLICHYL PYROPHOSPHATE GLUCOSYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

Alg10

ALG10 alpha-1,2-glucosyltransferase

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

gny

garnysstan

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

xit

xiantuan

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

DOLICHYL PYROPHOSPHATE MANNOSYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

Alg1

ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

Alg2

ALG2, alpha-1,3/1,6-mannosyltransferase

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

Alg3

ALG3, alpha-1,3- mannosyltransferase

l(2)not, l(2)tid, lethal(2)tumorous imaginal discs, tid, lethal(2) tumorous imaginal discs

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

Alg9

ALG9, alpha-1,2-mannosyltransferase

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

Alg11

ALG11, alpha-1,2-mannosyltransferase

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

Alg12

Alg12 alpha-1,6-mannosyltransferase

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

GLUCURONOSYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

(FlyBase, 2017-)

(FlyBase, 2017-)

(FlyBase, 2017-)

(FlyBase, 2017-)

Chondroitin polymerizing factor

(FlyBase, 2017-)

Chsy

Chondroitin sulfate synthase

(FlyBase, 2017-)

GlcAT-I

Glucuronyltransferase I

dGlcAT-I

(Li et al., 2020, FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015, Kim et al., 2003)

GlcAT-P

Glucuronyltransferase P

dGlcAT-P

(Li et al., 2020, FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015, Kim et al., 2003)

GlcAT-S

Glucuronyltransferase S

dGlcAT-S

(Li et al., 2020, FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015, Kim et al., 2003)

sotv

sister of tout-velu

Ext2, DEXT2

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

ttv

tout-velu

l(2)05282, DEXT1, l(2)00681, l(2)k03617

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

GPI MANNOSYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

PIG-B

Phosphatidylinositol glycan anchor biosynthesis class B

PIGB

(FlyBase, 2017-, Satoh et al., 2013)

PIG-M

Phosphatidylinositol glycan anchor biosynthesis class M

(FlyBase, 2017-, Satoh et al., 2013)

PIG-V

Phosphatidylinositol glycan anchor biosynthesis class V

(FlyBase, 2017-, Satoh et al., 2013)

PIG-Z

Phosphatidylinositol glycan anchor biosynthesis class Z

(FlyBase, 2017-, Satoh et al., 2013)

MANNOSYL-GLYCOPROTEIN N-ACETYLGLUCOSAMINYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

Mgat1

Mannosyl (α-1,3-)-glycoprotein β-1,2-N-acetylglucosaminyltransferase

N-acetylglucosaminyltransferase I, dMGAT1

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

Mgat2

Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase

dMGAT2

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

Mgat3

beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

Mgat4a

alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase a

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

Mgat4b

alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase b

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

OLIGOSACCHARYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

Stt3A

Catalytic subunit 3A of the oligosaccharyltransferase complex

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

Stt3B

Catalytic subunit 3B of the oligosaccharyltransferase complex

OstStt3, l(3)j2D9, Oligosaccharyl transferase 3

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

PEPTIDE-O-FUCOSYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

O-fut1

O-fucosyltransferase 1

Ofut1, neurotic, nti, O-fucosyl transferase, O-fut

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Roos et al., 2002)

O-fut2

O-fucosyltransferase 2

EG:BACN32G11.6, Ofut2

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Roos et al., 2002)

PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

PIG-A

Phosphatidylinositol glycan anchor biosynthesis class A

(FlyBase, 2017-, Eisenhaber et al., 2003)

POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

CG10000

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Tran et al., 2012, Tian and Ten Hagen, 2006, Ten Hagen et al., 2003, Schwientek et al., 2002)

CG31776

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Tran et al., 2012, Tian and Ten Hagen, 2006, Ten Hagen et al., 2003, Schwientek et al., 2002)

Pgant1

Polypeptide N-Acetylgalactosaminyltransferase 1

GalNAc-T1

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Tran et al., 2012, Tian and Ten Hagen, 2006, Ten Hagen et al., 2003, Schwientek et al., 2002)

Pgant2

Polypeptide N-Acetylgalactosaminyltransferase 2

polypeptide GalNAc transferase 2

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Tran et al., 2012, Tian and Ten Hagen, 2006, Ten Hagen et al., 2003, Schwientek et al., 2002)

Pgant3

Polypeptide N-Acetylgalactosaminyltransferase 3

BcDNA:GH09147

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Tran et al., 2012, Tian and Ten Hagen, 2006, Ten Hagen et al., 2003, Schwientek et al., 2002)

Pgant4

Polypeptide N-Acetylgalactosaminyltransferase 4

polypeptide GalNAc transferase 4

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Tran et al., 2012, Tian and Ten Hagen, 2006, Ten Hagen et al., 2003, Schwientek et al., 2002)

Pgant5

Polypeptide N-Acetylgalactosaminyltransferase 5

pgnat5

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Tran et al., 2012, Tian and Ten Hagen, 2006, Ten Hagen et al., 2003, Schwientek et al., 2002)

Pgant6

Polypeptide N-Acetylgalactosaminyltransferase 6

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Tran et al., 2012, Tian and Ten Hagen, 2006, Ten Hagen et al., 2003, Schwientek et al., 2002)

Pgant7

Polypeptide N-Acetylgalactosaminyltransferase 7

GalNAc-T2

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Tran et al., 2012, Tian and Ten Hagen, 2006, Ten Hagen et al., 2003, Schwientek et al., 2002)

Pgant8

Polypeptide N-Acetylgalactosaminyltransferase 8

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Tran et al., 2012, Tian and Ten Hagen, 2006, Ten Hagen et al., 2003, Schwientek et al., 2002)

Pgant9

Polypeptide N-Acetylgalactosaminyltransferase 9

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Tran et al., 2012, Tian and Ten Hagen, 2006, Ten Hagen et al., 2003, Schwientek et al., 2002)

Pgant35A

Polypeptide N-acetylgalactosaminyltransferase 35A

l(2)35Aa, l(2)br12, dGalNAc-T1, br12, BG:DS01068.8

(FlyBase, 2017-, Yamamoto-Hino et al., 2015, Tran et al., 2012, Tian and Ten Hagen, 2006, Ten Hagen et al., 2003, Schwientek et al., 2002)

PROCOLLAGEN GALACTOSYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

CG31915

(FlyBase, 2017-)

Plod

procollagen lysyl hydroxylase

dPlod

(FlyBase, 2017-)

PROTEIN O-GLCNAC TRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

Eogt

EGF-domain O-GlcNAc transferase

(Li et al., 2020, FlyBase, 2017-, Walski et al., 2017)

sxc

super sex combs

Ogt, O-GlcNAc transferase, l(2)NC130, l(2)02637, O-glycosyltransferase

(Li et al., 2020, FlyBase, 2017-, Walski et al., 2017)

PROTEIN O-MANNOSYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

rotated abdomen

dPOMT1, POMT1

(Li et al., 2020, FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

Tmtc1

Transmembrane O-mannosyltransferase targeting cadherins 1

(Eisenhaber et al., 2021, FlyBase, 2017-)

Tmtc2

Transmembrane O-mannosyltransferase targeting cadherins 2

(Eisenhaber et al., 2021, FlyBase, 2017-)

Tmtc3

Transmembrane O-mannosyltransferase targeting cadherins 3

(Eisenhaber et al., 2021, FlyBase, 2017-)

Tmtc4

Transmembrane O-mannosyltransferase targeting cadherins 4

(Eisenhaber et al., 2021, FlyBase, 2017-)

twisted

POMT2, EG:34F3.7, dPOMT2, Protein O-mannosyltransferase 2

(Li et al., 2020, FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

PROTEOGLYCAN N-ACETYLGLUCOSAMINYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

botv

brother of tout-velu

DEXT3

(FlyBase, 2017-)

sotv

sister of tout-velu

Ext2, DEXT2

(FlyBase, 2017-)

ttv

tout-velu

l(2)05282, DEXT1, l(2)00681, l(2)k03617

(FlyBase, 2017-)

UNCLASSIFIED GALACTOSYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

β3GalTII

β-1,3-Galactosyltransferase II

Galactosyltransferase II

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

β4GalT7

β-4-galactosyltransferase 7

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

CG3655

EG:103E12.3

(FlyBase, 2017-)

CG9395

(FlyBase, 2017-)

CG11384

EG:BACR42I17.3

(FlyBase, 2017-)

CG12715

(FlyBase, 2017-)

CG12910

(FlyBase, 2017-)

UNCLASSIFIED GLUCOSYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

CG31139

(FlyBase, 2017-)

CG33090

BG:DS01068.2

(FlyBase, 2017-)

Gba1a

Glucocerebrosidase 1a

dGBA1a

(FlyBase, 2017-)

Gba1b

Glucocerebrosidase 1b

dGBA1b

(FlyBase, 2017-)

GlcT

Glucosylceramide synthase

GlcT-1, ceramide glucosyltransferase, dGlcCerT, DGlcT-1

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

Glys

Glycogen synthase

(FlyBase, 2017-)

Gyg

Glycogenin

(FlyBase, 2017-)

Plod

procollagen lysyl hydroxylase

dPlod

(FlyBase, 2017-)

rumi

dRumi

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

Tps1

Trehalose-6-phosphate synthase 1

BcDNA:GH08860, l(2)k08903, jf5, tps, trehalose synthase

(FlyBase, 2017-)

Uggt

UDP-glucose-glycoprotein glucosyltransferase

Ugt, UDP-glucose:glycoprotein glucosyltransferase, GT

(FlyBase, 2017-, Walski et al., 2017, Yamamoto-Hino et al., 2015)

wol

wollknaeuel

wollknauel, alg5

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

UNCLASSIFIED HEXOSYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

Agbe

1,4-Alpha-glucan branching enzyme

(FlyBase, 2017-)

Agl

Glycogen debranching enzyme

(FlyBase, 2017-)

Amyrel

Amylase related

(Feller et al., 2021)

CG9109

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

Glyp

Glycogen phosphorylase

GP, Glp1

(FlyBase, 2017-)

UNCLASSIFIED MANNOSYLTRANSFERASES

Gene Symbol

Gene Name

Also Known As

Source Material for Membership

CG6659

(FlyBase, 2017-)

CG15914

(FlyBase, 2017-)

Dpm1

Dolichyl-phosphate mannosyltransferase subunit 1

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

egh

egghead

zw4, l(1)zw4, zw-4, EG:BACR25B3.8, zeste-white 4

(FlyBase, 2017-, Yamamoto-Hino et al., 2015)

External Data

Equivalent Group(s)

Other resource(s)

Synonyms and Secondary IDs

Synonym(s)

HEXOSYLTRANSFERASES

HTF

HEXT

Secondary FlyBase ID(s)

References (22)

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