FB2024_03 , released June 25, 2024
Allele: Dmel\Psn143
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General Information
Symbol
Dmel\Psn143
Species
D. melanogaster
Name
FlyBase ID
FBal0156040
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
    Nature of the Allele
    Mutagen
    Progenitor genotype
    Cytology
    Description

    268bp deletion that removes sequence encoding Psn amino acids 136-224.

    Deletion and/or splice site mutation resulting in deletion of the amino acids between the first transmembrane domain and the middle of the fourth transmembrane domain.

    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 1 )
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Psn9/Psn143 trans-heterozygotes display normal thorax morphology.

    Heterozygotes show no visible phenotypes.

    Psn9/Psn143 flies have a reduced and roughened eye and distal wing vein thickening, while the notum is relatively normal.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Enhanced by
    Statement
    Reference

    Psn9/Psn143 has visible phenotype, enhanceable by dacMEE-2

    Psn9/Psn143 has visible phenotype, enhanceable by eyaSLE-2

    Psn9/Psn143 has visible phenotype, enhanceable by γTub23Cbmps3

    Psn9/Psn143 has visible phenotype, enhanceable by γTub23Cbmps4

    Psn9/Psn143 has visible phenotype, enhanceable by γTub23Cbmps5

    Psn9/Psn143 has visible phenotype, enhanceable by soSHE-7

    Psn9/Psn143 has visible phenotype, enhanceable by dacMHE-1

    Psn9/Psn143 has visible phenotype, enhanceable by soSKE-1

    Psn9/Psn143 has visible phenotype, enhanceable by Spt5MGE-3

    Psn9/Psn143 has visible phenotype, enhanceable by Spt5SIE-27

    Psn9/Psn143 has visible phenotype, enhanceable by Sunspecified

    Psn9/Psn143 has visible phenotype, enhanceable by vgSDE-1

    Psn9/Psn143 has visible phenotype, enhanceable by vgSGE-11

    Psn9/Psn143 has visible phenotype, enhanceable by AP-1μSAE-10

    Psn9/Psn143 has visible phenotype, enhanceable by DeltaMIE-22

    Psn9/Psn143 has visible phenotype, enhanceable by DeltaPFE-6

    Psn9/Psn143 has visible phenotype, enhanceable by DeltaPGE-2

    Psn9/Psn143 has visible phenotype, enhanceable by dacSFE-8

    Psn9/Psn143 has visible phenotype, enhanceable by DeltaSDE-4

    Psn9/Psn143 has visible phenotype, enhanceable by DeltaSHE-11

    Psn9/Psn143 has visible phenotype, enhanceable by glSAE-9

    Psn9/Psn143 has visible phenotype, enhanceable by hhPIE-7

    Psn9/Psn143 has visible phenotype, enhanceable by hhSCE-2

    Psn9/Psn143 has visible phenotype, enhanceable by hhSFE-4

    Psn9/Psn143 has visible phenotype, enhanceable by hhSGE-2

    Psn9/Psn143 has visible phenotype, enhanceable by hhSHE-2

    Psn9/Psn143 has visible phenotype, enhanceable by hhSLE-1

    Psn9/Psn143 has visible phenotype, enhanceable by kkvSIE-29

    Psn9/Psn143 has visible phenotype, enhanceable by dpyPGE-8

    Psn9/Psn143 has visible phenotype, enhanceable by opaSIE-19

    Psn9/Psn143 has visible phenotype, enhanceable by opaSIE-24

    Psn9/Psn143 has visible phenotype, enhanceable by opaSJE-2

    Psn9/Psn143 has visible phenotype, enhanceable by opaSKE-5

    Psn9/Psn143 has visible phenotype, enhanceable by Rap1PIE-6

    Psn9/Psn143 has visible phenotype, enhanceable by Ras85DMAE-2

    Psn9/Psn143 has visible phenotype, enhanceable by Ras85DMDE-7

    Psn9/Psn143 has visible phenotype, enhanceable by eyaSJE-1

    Psn9/Psn143 has visible phenotype, enhanceable by AP-1μSHE-11

    Psn9/Psn143 has visible phenotype, enhanceable by NctPIE-6

    Psn9/Psn143 has visible phenotype, enhanceable by NctSGE-3

    Psn9/Psn143 has visible phenotype, enhanceable by NctSGE-8

    Psn9/Psn143 has visible phenotype, enhanceable by NctSGE-9

    Psn9/Psn143 has visible phenotype, enhanceable by NctSGE-10

    Psn9/Psn143 has visible phenotype, enhanceable by NctSIE-28

    Psn9/Psn143 has visible phenotype, enhanceable by NctSIE-22

    Suppressed by
    Statement
    Reference

    Psn9/Psn143 has visible phenotype, suppressible by HSDS-1

    Psn9/Psn143 has visible phenotype, suppressible by HSLS-1

    Enhancer of
    Statement
    Reference
    Other
    Statement
    Reference

    Psn143/Psn[+], opaA3 has visible phenotype

    Psn143/Psn[+], opaB28 has visible phenotype

    Phenotype Manifest In
    Enhanced by
    Statement
    Reference

    Psn9/Psn143 has eye phenotype, enhanceable by dacMEE-2

    Psn9/Psn143 has eye phenotype, enhanceable by eyaSLE-2

    Psn9/Psn143 has eye phenotype, enhanceable by γTub23Cbmps3

    Psn9/Psn143 has eye phenotype, enhanceable by γTub23Cbmps4

    Psn9/Psn143 has eye phenotype, enhanceable by γTub23Cbmps5

    Psn9/Psn143 has eye phenotype, enhanceable by soSHE-7

    Psn9/Psn143 has eye phenotype, enhanceable by soSKE-1

    Psn9/Psn143 has eye phenotype, enhanceable by Spt5MGE-3

    Psn9/Psn143 has eye phenotype, enhanceable by Spt5SIE-27

    Psn9/Psn143 has eye phenotype, enhanceable by Sunspecified

    Psn9/Psn143 has eye phenotype, enhanceable by vgSDE-1

    Psn9/Psn143 has eye phenotype, enhanceable by dacMHE-1

    Psn9/Psn143 has eye phenotype, enhanceable by vgSGE-11

    Psn9/Psn143 has eye phenotype, enhanceable by AP-1μSAE-10

    Psn9/Psn143 has eye phenotype, enhanceable by DeltaMIE-22

    Psn9/Psn143 has eye phenotype, enhanceable by DeltaPFE-6

    Psn9/Psn143 has eye phenotype, enhanceable by DeltaPGE-2

    Psn9/Psn143 has eye phenotype, enhanceable by DeltaSDE-4

    Psn9/Psn143 has eye phenotype, enhanceable by DeltaSHE-11

    Psn9/Psn143 has eye phenotype, enhanceable by glSAE-9

    Psn9/Psn143 has eye phenotype, enhanceable by hhPIE-7

    Psn9/Psn143 has eye phenotype, enhanceable by hhSCE-2

    Psn9/Psn143 has eye phenotype, enhanceable by dacSFE-8

    Psn9/Psn143 has eye phenotype, enhanceable by hhSFE-4

    Psn9/Psn143 has eye phenotype, enhanceable by hhSGE-2

    Psn9/Psn143 has eye phenotype, enhanceable by hhSHE-2

    Psn9/Psn143 has eye phenotype, enhanceable by hhSLE-1

    Psn9/Psn143 has eye phenotype, enhanceable by kkvSIE-29

    Psn9/Psn143 has eye phenotype, enhanceable by opaSIE-19

    Psn9/Psn143 has eye phenotype, enhanceable by opaSIE-24

    Psn9/Psn143 has eye phenotype, enhanceable by opaSJE-2

    Psn9/Psn143 has eye phenotype, enhanceable by opaSKE-5

    Psn9/Psn143 has eye phenotype, enhanceable by Rap1PIE-6

    Psn9/Psn143 has eye phenotype, enhanceable by dpyPGE-8

    Psn9/Psn143 has eye phenotype, enhanceable by Ras85DMAE-2

    Psn9/Psn143 has eye phenotype, enhanceable by Ras85DMDE-7

    Psn9/Psn143 has eye phenotype, enhanceable by AP-1μSHE-11

    Psn9/Psn143 has eye phenotype, enhanceable by NctPIE-6

    Psn9/Psn143 has eye phenotype, enhanceable by NctSGE-3

    Psn9/Psn143 has eye phenotype, enhanceable by NctSGE-8

    Psn9/Psn143 has eye phenotype, enhanceable by NctSGE-9

    Psn9/Psn143 has eye phenotype, enhanceable by eyaSJE-1

    Psn9/Psn143 has eye phenotype, enhanceable by NctSGE-10

    Psn9/Psn143 has eye phenotype, enhanceable by NctSIE-28

    Psn9/Psn143 has eye phenotype, enhanceable by NctSIE-22

    NOT Enhanced by
    Statement
    Reference

    Psn9/Psn143 has phenotype, non-enhanceable by aph-1[+]/aph-1D35

    Suppressed by
    Statement
    Reference

    Psn9/Psn143 has eye phenotype, suppressible by HSDS-1

    Psn9/Psn143 has eye phenotype, suppressible by HSLS-1

    NOT suppressed by
    Statement
    Reference

    Psn9/Psn143 has phenotype, non-suppressible by aph-1[+]/aph-1D35

    Enhancer of
    Statement
    Reference
    Other
    Statement
    Reference
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Psn143/+ dominantly enhances the frequency of R3-R3 symmetrical clusters induced by Scer\GAL4hs.2sev>hbsVDRC.cUa.

    Psn143/+ enhances the Scer\GAL4hs.2sev>hbsScer\UAS.cDa-induced planar cell polarity (PCP) phenotype in the eye.

    Psn9/Psn143 strongly enhances the thoracic bristle loss of Df(2R)hbsj5/Df(2R)ED2423 mutants.

    Psn9/Psn143 strongly enhances the thoracic bristle loss of hbs459/Df(2R)ED2423 mutants.

    γTub23Cbmps1 ; Psn143/+ flies have bumps and notching on the wing.

    γTub23Cbmps2 ; Psn143/+ flies have bumps and notching on the wing.

    opaA3 Psn143/+ flies have tufted vibrissae.

    opaB28 Psn143/+ flies have tufted vibrissae.

    dpMFE-1 ; Psn9/Psn143 flies have pits in the notum.

    dpPIE-10 ; Psn9/Psn143 flies have pits in the notum.

    γTub23Cbmps3 ; Psn9/Psn143 flies have bumps and notching on the wing and wing vein thickening.

    γTub23Cbmps4 ; Psn9/Psn143 flies have bumps and notching on the wing and wing vein thickening.

    vgPHE-4 ; Psn9/Psn143 flies have notches on the wing.

    vgSDE-1 ; Psn9/Psn143 flies have notches on the wing.

    vgSGE-4 ; Psn9/Psn143 flies have notches on the wing.

    vgSGE-11 ; Psn9/Psn143 flies have notches on the wing.

    AP-47SAE-10 Psn9/Psn143 flies show wing vein thickening.

    AP-47SHE-11 Psn9/Psn143 flies show wing vein thickening and low penetrance pupal lethality.

    DlMIE-22 Psn9/Psn143 flies show wing vein thickening.

    DlPFE-6 Psn9/Psn143 flies show wing vein thickening.

    DlPGE-2 Psn9/Psn143 flies show wing vein thickening.

    DlSDE-4 Psn9/Psn143 flies show wing vein thickening.

    DlSHE-5 Psn9/Psn143 flies have held out wings which show notching.

    DlSHE-11 Psn9/Psn143 flies show wing vein thickening and low penetrance pupal lethality.

    DlSIE-36 Psn9/Psn143 flies show wing vein thickening and low penetrance pupal lethality.

    HPFE-1 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss.

    HPGE-1 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss.

    HPGE-4 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss.

    HPGE-6 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss.

    HSDS-1 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss.

    HSLS-1 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss.

    hhPIE-7 Psn9/Psn143 flies have extra vein material between wing veins 2 and 3.

    hhSCE-2 Psn9/Psn143 flies show wing notching.

    nctSGE-8 Psn9/Psn143 flies show wing vein thickening and notching of the wing.

    nctSGE-9 Psn9/Psn143 flies show wing vein thickening and notching of the wing.

    nctSIE-28 Psn9/Psn143 flies show wing vein thickening and notching of the wing.

    nctSIE-22 Psn9/Psn143 flies show notching of the wing and some microchaetae are missing.

    opaSIE-19 Psn9/Psn143 flies have tufted vibrissae.

    opaSIE-24 Psn9/Psn143 flies have tufted vibrissae.

    opaSJE-2 Psn9/Psn143 flies have tufted vibrissae and wing notching.

    opaSKE-5 Psn9/Psn143 flies have tufted vibrissae.

    vgPHE-4 ; Psn143/+ flies show mild wing nicking.

    AP-47SAE-10/AP-47SHE-11 Psn9/Psn143 flies have dorsal and ventral wing notching, enhanced wing vein thickening and show loss of notal microchaetae.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (3)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    References (10)