Date: Thu, 06 May 2004 13:32:18 \-0500 To: rd120@XXXX From: Kevin Cook <kcook@XXXX> Subject: Psn9, Psn143, Psn145 and Psn227 Cc: flybase-updatesXXXX, Annette Parks <annettepXXXX> The following information was provided by Annette Parks of Exelixis, Inc. (5/04). Psn9 was induced with EMS and results in a L499Q change in the 541 amino acid Psn isoform. It appears to be hypomorphic. Psn143 is a deletion and/or splice site mutation resulting in deletion of the amino acids between the first transmembrane domain and the middle of the fourth transmembrane domain. It behaves as a null allele. Psn145 results in loss of amino acids 51 to 105. Psn227 results in a change of Q41 to stop. __________________________________________________________ Kevin Cook, Ph.D. Bloomington Drosophila Stock Center Department of Biology http://flystocks.bio.indiana.edu Jordan Hall 142 Indiana University 812-856-1213 1001 E. Third St. 812-855-2577 (fax) Bloomington, IN 47405-3700 kcook@XXXX