FB2024_03 , released June 25, 2024
Allele: Dmel\Psn9
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General Information
Symbol
Dmel\Psn9
Species
D. melanogaster
Name
FlyBase ID
FBal0156024
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Nature of the Allele
Progenitor genotype
Cytology
Description

Amino acid replacement: L499Q.

Amino acid numbering refers to the 541 amino acid Psn isoform.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Nucleotide change:

T20434919A

Amino acid change:

L499Q | Psn-PA; L485Q | Psn-PB; L466Q | Psn-PC; L485Q | Psn-PD; L499Q | Psn-PE

Reported amino acid change:

L499Q

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Psn9/Psn143 trans-heterozygotes display normal thorax morphology.

Psn9/Psn143 flies have a reduced and roughened eye and distal wing vein thickening, while the notum is relatively normal.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

Psn9/Psn143 has visible phenotype, enhanceable by dacMEE-2

Psn9/Psn143 has visible phenotype, enhanceable by eyaSLE-2

Psn9/Psn143 has visible phenotype, enhanceable by γTub23Cbmps3

Psn9/Psn143 has visible phenotype, enhanceable by γTub23Cbmps4

Psn9/Psn143 has visible phenotype, enhanceable by γTub23Cbmps5

Psn9/Psn143 has visible phenotype, enhanceable by soSHE-7

Psn9/Psn143 has visible phenotype, enhanceable by dacMHE-1

Psn9/Psn143 has visible phenotype, enhanceable by soSKE-1

Psn9/Psn143 has visible phenotype, enhanceable by Spt5MGE-3

Psn9/Psn143 has visible phenotype, enhanceable by Spt5SIE-27

Psn9/Psn143 has visible phenotype, enhanceable by Sunspecified

Psn9/Psn143 has visible phenotype, enhanceable by vgSDE-1

Psn9/Psn143 has visible phenotype, enhanceable by vgSGE-11

Psn9/Psn143 has visible phenotype, enhanceable by AP-1μSAE-10

Psn9/Psn143 has visible phenotype, enhanceable by DeltaMIE-22

Psn9/Psn143 has visible phenotype, enhanceable by DeltaPFE-6

Psn9/Psn143 has visible phenotype, enhanceable by DeltaPGE-2

Psn9/Psn143 has visible phenotype, enhanceable by dacSFE-8

Psn9/Psn143 has visible phenotype, enhanceable by DeltaSDE-4

Psn9/Psn143 has visible phenotype, enhanceable by DeltaSHE-11

Psn9/Psn143 has visible phenotype, enhanceable by glSAE-9

Psn9/Psn143 has visible phenotype, enhanceable by hhPIE-7

Psn9/Psn143 has visible phenotype, enhanceable by hhSCE-2

Psn9/Psn143 has visible phenotype, enhanceable by hhSFE-4

Psn9/Psn143 has visible phenotype, enhanceable by hhSGE-2

Psn9/Psn143 has visible phenotype, enhanceable by hhSHE-2

Psn9/Psn143 has visible phenotype, enhanceable by hhSLE-1

Psn9/Psn143 has visible phenotype, enhanceable by kkvSIE-29

Psn9/Psn143 has visible phenotype, enhanceable by dpyPGE-8

Psn9/Psn143 has visible phenotype, enhanceable by opaSIE-19

Psn9/Psn143 has visible phenotype, enhanceable by opaSIE-24

Psn9/Psn143 has visible phenotype, enhanceable by opaSJE-2

Psn9/Psn143 has visible phenotype, enhanceable by opaSKE-5

Psn9/Psn143 has visible phenotype, enhanceable by Rap1PIE-6

Psn9/Psn143 has visible phenotype, enhanceable by Ras85DMAE-2

Psn9/Psn143 has visible phenotype, enhanceable by Ras85DMDE-7

Psn9/Psn143 has visible phenotype, enhanceable by AP-1μSHE-11

Psn9/Psn143 has visible phenotype, enhanceable by eyaSJE-1

Psn9/Psn143 has visible phenotype, enhanceable by NctPIE-6

Psn9/Psn143 has visible phenotype, enhanceable by NctSGE-3

Psn9/Psn143 has visible phenotype, enhanceable by NctSGE-8

Psn9/Psn143 has visible phenotype, enhanceable by NctSGE-9

Psn9/Psn143 has visible phenotype, enhanceable by NctSGE-10

Psn9/Psn143 has visible phenotype, enhanceable by NctSIE-28

Psn9/Psn143 has visible phenotype, enhanceable by NctSIE-22

Suppressed by
Statement
Reference

Psn9/Psn143 has visible phenotype, suppressible by HSDS-1

Psn9/Psn143 has visible phenotype, suppressible by HSLS-1

Enhancer of
Statement
Reference
Other
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

Psn9/Psn143 has eye phenotype, enhanceable by dacMEE-2

Psn9/Psn143 has eye phenotype, enhanceable by eyaSLE-2

Psn9/Psn143 has eye phenotype, enhanceable by γTub23Cbmps3

Psn9/Psn143 has eye phenotype, enhanceable by γTub23Cbmps4

Psn9/Psn143 has eye phenotype, enhanceable by γTub23Cbmps5

Psn9/Psn143 has eye phenotype, enhanceable by soSHE-7

Psn9/Psn143 has eye phenotype, enhanceable by soSKE-1

Psn9/Psn143 has eye phenotype, enhanceable by Spt5MGE-3

Psn9/Psn143 has eye phenotype, enhanceable by Spt5SIE-27

Psn9/Psn143 has eye phenotype, enhanceable by Sunspecified

Psn9/Psn143 has eye phenotype, enhanceable by vgSDE-1

Psn9/Psn143 has eye phenotype, enhanceable by dacMHE-1

Psn9/Psn143 has eye phenotype, enhanceable by vgSGE-11

Psn9/Psn143 has eye phenotype, enhanceable by AP-1μSAE-10

Psn9/Psn143 has eye phenotype, enhanceable by DeltaMIE-22

Psn9/Psn143 has eye phenotype, enhanceable by DeltaPFE-6

Psn9/Psn143 has eye phenotype, enhanceable by DeltaPGE-2

Psn9/Psn143 has eye phenotype, enhanceable by DeltaSDE-4

Psn9/Psn143 has eye phenotype, enhanceable by DeltaSHE-11

Psn9/Psn143 has eye phenotype, enhanceable by glSAE-9

Psn9/Psn143 has eye phenotype, enhanceable by hhPIE-7

Psn9/Psn143 has eye phenotype, enhanceable by hhSCE-2

Psn9/Psn143 has eye phenotype, enhanceable by dacSFE-8

Psn9/Psn143 has eye phenotype, enhanceable by hhSFE-4

Psn9/Psn143 has eye phenotype, enhanceable by hhSGE-2

Psn9/Psn143 has eye phenotype, enhanceable by hhSHE-2

Psn9/Psn143 has eye phenotype, enhanceable by hhSLE-1

Psn9/Psn143 has eye phenotype, enhanceable by kkvSIE-29

Psn9/Psn143 has eye phenotype, enhanceable by opaSIE-19

Psn9/Psn143 has eye phenotype, enhanceable by opaSIE-24

Psn9/Psn143 has eye phenotype, enhanceable by opaSJE-2

Psn9/Psn143 has eye phenotype, enhanceable by opaSKE-5

Psn9/Psn143 has eye phenotype, enhanceable by Rap1PIE-6

Psn9/Psn143 has eye phenotype, enhanceable by dpyPGE-8

Psn9/Psn143 has eye phenotype, enhanceable by Ras85DMAE-2

Psn9/Psn143 has eye phenotype, enhanceable by Ras85DMDE-7

Psn9/Psn143 has eye phenotype, enhanceable by AP-1μSHE-11

Psn9/Psn143 has eye phenotype, enhanceable by NctPIE-6

Psn9/Psn143 has eye phenotype, enhanceable by NctSGE-3

Psn9/Psn143 has eye phenotype, enhanceable by NctSGE-8

Psn9/Psn143 has eye phenotype, enhanceable by NctSGE-9

Psn9/Psn143 has eye phenotype, enhanceable by NctSGE-10

Psn9/Psn143 has eye phenotype, enhanceable by eyaSJE-1

Psn9/Psn143 has eye phenotype, enhanceable by NctSIE-28

Psn9/Psn143 has eye phenotype, enhanceable by NctSIE-22

NOT Enhanced by
Statement
Reference

Psn9/Psn143 has phenotype, non-enhanceable by aph-1[+]/aph-1D35

Suppressed by
Statement
Reference

Psn9/Psn143 has eye phenotype, suppressible by HSDS-1

Psn9/Psn143 has eye phenotype, suppressible by HSLS-1

NOT suppressed by
Statement
Reference

Psn9/Psn143 has phenotype, non-suppressible by aph-1[+]/aph-1D35

Enhancer of
Statement
Reference
Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Psn9/+ dominantly enhances the frequency of R3-R3 symmetrical clusters induced by Scer\GAL4hs.2sev>hbsVDRC.cUa.

Psn9/Psn143 strongly enhances the thoracic bristle loss of Df(2R)hbsj5/Df(2R)ED2423 mutants.

Psn9/Psn143 strongly enhances the thoracic bristle loss of hbs459/Df(2R)ED2423 mutants.

dpMFE-1 ; Psn9/Psn143 flies have pits in the notum.

dpPIE-10 ; Psn9/Psn143 and dpPIE-10 ; Psn9/+ flies have pits in the notum.

γTub23Cbmps3 ; Psn9/Psn143 flies have bumps and notching on the wing and wing vein thickening.

γTub23Cbmps4 ; Psn9/Psn143 flies have bumps and notching on the wing and wing vein thickening.

vgPHE-4 ; Psn9/Psn143 flies have notches on the wing.

vgSDE-1 ; Psn9/Psn143 flies have notches on the wing.

vgSGE-4 ; Psn9/Psn143 flies have notches on the wing.

vgSGE-11 ; Psn9/Psn143 flies have notches on the wing.

AP-47SAE-10 Psn9/Psn143 flies show wing vein thickening.

AP-47SHE-11 Psn9/Psn143 flies show wing vein thickening and low penetrance pupal lethality.

DlMIE-22 Psn9/Psn143 flies show wing vein thickening.

DlPFE-6 Psn9/Psn143 flies show wing vein thickening.

DlPGE-2 Psn9/Psn143 flies show wing vein thickening.

DlSDE-4 Psn9/Psn143 flies show wing vein thickening.

DlSHE-5 Psn9/Psn143 flies have held out wings which show notching.

DlSHE-11 Psn9/Psn143 flies show wing vein thickening and low penetrance pupal lethality.

DlSIE-36 Psn9/Psn143 flies show wing vein thickening and low penetrance pupal lethality.

HPFE-1 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss.

HPGE-1 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss.

HPGE-4 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss.

HPGE-6 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss.

HSDS-1 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss.

HSLS-1 Psn9/Psn143 flies show bristle shaft to socket transformations and wing vein loss.

hhPIE-7 Psn9/Psn143 flies have extra vein material between wing veins 2 and 3.

hhSCE-2 Psn9/Psn143 flies show wing notching.

nctSGE-8 Psn9/Psn143 flies show wing vein thickening and notching of the wing.

nctSGE-9 Psn9/Psn143 flies show wing vein thickening and notching of the wing.

nctSIE-28 Psn9/Psn143 flies show wing vein thickening and notching of the wing.

nctSIE-22 Psn9/Psn143 flies show notching of the wing and some microchaetae are missing.

opaSIE-19 Psn9/Psn143 flies have tufted vibrissae.

opaSIE-24 Psn9/Psn143 flies have tufted vibrissae.

opaSJE-2 Psn9/Psn143 flies have tufted vibrissae and wing notching.

opaSKE-5 Psn9/Psn143 flies have tufted vibrissae.

AP-47SAE-10/AP-47SHE-11 Psn9/Psn143 flies have dorsal and ventral wing notching, enhanced wing vein thickening and show loss of notal microchaetae.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (4)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (4)