FB2024_03 , released June 25, 2024
Allele: Dmel\Diap1UAS.cHa
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General Information
Symbol
Dmel\Diap1UAS.cHa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Hay
FlyBase ID
FBal0138121
Feature type
allele
Associated gene
Dmel\Diap1
Associated Insertion(s)
Carried in Construct
P{UAS-DIAP1.H}
Also Known As
UAS-DIAP1, UAS-DIAP, UAS.DIAP1, UAS- DIAP1, UASdiap1
Key Links
Transgenic product class
wild_type
(Lohmann et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Lohmann et al., 2002)
Mutagen
in vitro construct
(Lohmann et al., 2002)
Progenitor genotype
Carried in construct
P{UAS-DIAP1.H}
Cytology
Description

UAS sequences drive expression of Diap1.

(Lohmann et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Diap1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  cancer
      CEA with hepRNAi.UAS
      (Wang et al., 2023)
      Modifiers Based on Experimental Evidence ( 1 )
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Class IV dendritic arborization neurons expressing Diap1UAS.cHa under the control of Scer\GAL4DcG exhibit a similar proportion of dendrite fragmentation/clearing following dendrite injury, as compared to controls.

      (Sapar et al., 2018)

      Third instar larvae expressing Diap1Scer\UAS.cHa under the control of either Scer\GAL4477 or Scer\GAL4ppk.PG show no defects in the dendritic arborization pattern of class IV dendritic arborizing neurons compared to controls, but the dendritic pruning of these neurons during pupariation is significantly delayed in pupae expressing Diap1Scer\UAS.cHa under Scer\GAL4ppk.PG.

      (Bhogal et al., 2016)

      Expression of Diap1Scer\UAS.cHa under the control of Scer\GAL4GMR.PU does not cause significant rough-eye phenotype compared to controls.

      (Lee et al., 2016)

      Expression of Diap1Scer\UAS.cHa under the control of Scer\GAL4bun-GSG5961 and Scer\GAL4GSG5966 (along with RU486 to induce expression via the GeneSwitch system) does not affect the growth of wild type clones in the adult posterior midgut.

      (Suijkerbuijk et al., 2016)

      Wing discs from third instar larvae expressing Diap1Scer\UAS.cHa under the control of Scer\GAL469B (using tub-Gal80[ts] to limit the time of expression) are significantly bigger compared to controls.

      (Waldron et al., 2015)

      Compared to controls, Diap1Scer\UAS.cHa Scer\GAL4ple.PF flies exposed to paraquat (to induce oxidative stress) show less degeneration of dopaminergic neurons compared to controls.

      (Shukla et al., 2014)

      Pruning of ddaC dendrites is delayed upon expression of thScer\UAS.cHa under the control of Scer\GAL4ppk.1.9. The degeneration of dendrites after severing is unaffected however.

      (Tao and Rolls, 2011)

      Expression of thScer\UAS.cHa in Crz-expressing neurons in the ventral nerve cord under the control of Scer\GAL4Crz has no affect on the levels of programmed cell death in these neurons.

      (Choi et al., 2006)

      Expression of thScer\UAS.cHa in the developing eye, driven by Scer\GAL4GMR.PF, results in a slight increase in the number of ommatidial cells.

      (Nolo et al., 2006)

      Overexpression of thScer\UAS.cHa under the control of Scer\GAL4ppk.1.9 suppresses dendritic branch removal.

      (Williams et al., 2006)

      Ectopic macrochaetae form on the scutellum in 60.8% of cases when thScer\UAS.cHa is expressed under the control of Scer\GAL4sca-P309.

      (Kanuka et al., 2005)

      When thScer\UAS.cHa is driven by Scer\GAL4T80, ectopic branches are seen in the arista. These are of intermediate length along the central core.

      (Cullen and McCall, 2004)

      When thScer\UAS.cHa is driven by Scer\GAL4wg.PM the segment boundary between the embryonic mandibular and maxillary segments is abolished. Also a fusion of the mandibular segment with the procephalic segment is seen.

      (Lohmann et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhanced by
      Suppressed by
      Statement
      Reference

      Diap1UAS.cHa has abnormal size | third instar larval stage phenotype, suppressible by pcm14/pcm14

      (Waldron et al., 2015)
      NOT suppressed by
      Enhancer of
      NOT Enhancer of
      Statement
      Reference

      Diap1UAS.cHa, Scer\GAL4elav.Switch.PO is a non-enhancer of abnormal memory | adult stage | RU486 conditional phenotype of Hsap\APP2xAPP.SP.UAS, Scer\GAL4elav.Switch.PO

      (Coelho et al., 2018)
      Suppressor of
      Statement
      Reference

      Scer\GAL4Act.PU/Diap1UAS.cHa is a suppressor of decreased cell number | somatic clone | larval stage phenotype of Ire1f02170

      (Zheng et al., 2023)

      Scer\GAL4Act.PU/Diap1UAS.cHa is a suppressor | partially of decreased cell number | somatic clone | larval stage phenotype of Ire1f02170, scrib1

      (Zheng et al., 2023)

      Scer\GAL4Act.PU/Diap1UAS.cHa is a suppressor | partially of decreased cell number | somatic clone | larval stage phenotype of scrib1

      (Zheng et al., 2023)

      Diap1UAS.cHa, Scer\GAL4GMR.PFa is a suppressor of visible | adult stage phenotype of Scer\GAL4GMR.PFa, Tom40UAS.Tag:FLAG,Tag:HA

      (Periasamy et al., 2022)

      Diap1UAS.cHa, Scer\GAL4Mef2.PR is a suppressor | partially of atrophy | pupal stage phenotype of Dlg5GD11943, Scer\GAL4Mef2.PR

      (Kaya-Çopur et al., 2021)

      Diap1UAS.cHa, Scer\GAL4Mef2.PR is a suppressor | partially of atrophy | pupal stage phenotype of Scer\GAL4Mef2.PR, ykiKK109756

      (Kaya-Çopur et al., 2021)

      Diap1UAS.cHa, Scer\GAL4ap.PU is a suppressor | partially of neoplasia | third instar larval stage phenotype of Ras85DV12.UAS, Scer\GAL4ap.PU

      (Soler Beatty et al., 2021)

      Scer\GAL4nub.PU/Diap1UAS.cHa is a suppressor | partially of visible | adult stage phenotype of RpS3Plac92, ykiB5

      (Wada et al., 2021)

      Scer\GAL4nub.PU/Diap1UAS.cHa is a suppressor | partially of decreased size | adult stage phenotype of RpS3Plac92, ykiB5

      (Wada et al., 2021)

      Scer\GAL4en.PU/Diap1UAS.cHa is a suppressor | partially of visible | adult stage phenotype of RpS3Plac92, ykiB5

      (Wada et al., 2021)

      Scer\GAL4en.PU/Diap1UAS.cHa is a suppressor | partially of decreased size | adult stage phenotype of RpS3Plac92, ykiB5

      (Wada et al., 2021)

      Scer\GAL4nub.PU/Diap1UAS.cHa is a suppressor | partially of increased cell death | larval stage phenotype of RpS3Plac92, ykiB5

      (Wada et al., 2021)

      Scer\GAL4en.PU/Diap1UAS.cHa is a suppressor | partially of increased cell death | larval stage phenotype of RpS3Plac92, ykiB5

      (Wada et al., 2021)

      Diap1UAS.cHa, Scer\GAL4en.PU is a suppressor | partially of decreased size | adult stage phenotype of Klp10AUAS.cYa, Scer\GAL4en.PU

      (Yang and Choi, 2021)

      Diap1UAS.cHa, Scer\GAL4en.PU is a suppressor | partially of visible | adult stage phenotype of Klp10AUAS.cYa, Scer\GAL4en.PU

      (Yang and Choi, 2021)

      Diap1UAS.cHa, Scer\GAL4en.PU is a suppressor of visible | adult stage phenotype of PatroninGD11946, Scer\GAL4en.PU

      (Yang and Choi, 2021)

      Diap1UAS.cHa, Scer\GAL4en.PU is a suppressor of decreased size | adult stage phenotype of PatroninGD11946, Scer\GAL4en.PU

      (Yang and Choi, 2021)

      Diap1UAS.cHa, Scer\GAL4en.PU is a suppressor of visible | adult stage phenotype of PatroninKK100898, Scer\GAL4en.PU

      (Yang and Choi, 2021)

      Diap1UAS.cHa, Scer\GAL4en.PU is a suppressor of decreased size | adult stage phenotype of PatroninKK100898, Scer\GAL4en.PU

      (Yang and Choi, 2021)

      Diap1UAS.cHa, Scer\GAL4GMR.PU is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4GMR.PU, SerTKK108310

      (Pham et al., 2020)

      Diap1UAS.cHa, Scer\GAL4GMR.PU is a suppressor | partially of increased occurrence of cell division | larval stage phenotype of Scer\GAL4GMR.PU, SerTKK108310

      (Pham et al., 2020)

      Diap1UAS.cHa, Scer\GAL4Burs.PL is a suppressor | partially of increased cell death | third instar larval stage phenotype of EcRB1-ΔC655.W650A.UAS, Scer\GAL4Burs.PL

      (Lee et al., 2019)

      Diap1UAS.cHa, Scer\GAL4Burs.PL is a suppressor | partially of abnormal neuroanatomy | third instar larval stage phenotype of EcRB1-ΔC655.W650A.UAS, Scer\GAL4Burs.PL

      (Lee et al., 2019)

      Diap1UAS.cHa, Scer\GAL4elav.Switch.PO is a suppressor of increased cell death | adult stage | RU486 conditional phenotype of Hsap\APP2xAPP.SP.UAS, Scer\GAL4elav.Switch.PO

      (Coelho et al., 2018)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of increased cell death | larval stage phenotype of Hsap\APP2xAPP.SP.UAS, Scer\GAL4GMR.PF

      (Coelho et al., 2018)

      Diap1UAS.cHa, Scer\GAL4GMR.PFa is a suppressor of visible | adult stage phenotype of DroncUAS.cSa, Scer\GAL4GMR.PFa

      (Sinenko, 2017)

      Diap1UAS.cHa, Scer\GAL4GMR.PFa is a suppressor of abnormal eye color phenotype of DroncUAS.cSa, Scer\GAL4GMR.PFa

      (Sinenko, 2017)

      Diap1UAS.cHa, Scer\GAL4GMR.PFa is a suppressor of visible | adult stage phenotype of DroncS130A.UAS.cSa, Scer\GAL4GMR.PFa

      (Sinenko, 2017)

      Diap1UAS.cHa, Scer\GAL4GMR.PFa is a suppressor of abnormal eye color phenotype of DroncS130A.UAS.cSa, Scer\GAL4GMR.PFa

      (Sinenko, 2017)

      Diap1UAS.cHa, Scer\GAL4477 is a suppressor of abnormal neuroanatomy | third instar larval stage phenotype of Scer\GAL4477, nanosRNAi.UAS.WIZ

      (Bhogal et al., 2016)

      Diap1UAS.cHa, Scer\GAL4477 is a suppressor of abnormal neuroanatomy | third instar larval stage phenotype of Scer\GAL4477, pumHMS01685

      (Bhogal et al., 2016)

      Diap1UAS.cHa, Scer\GAL4GMR.PU is a suppressor of visible | adult stage phenotype of Scer\GAL4GMR.PU, sraEY07182

      (Lee et al., 2016)

      Scer\GAL4bun-GSG5961, Scer\GAL4GSG5966, Diap1UAS.cHa is a suppressor | RU486 conditional of increased cell number | somatic clone phenotype of Apc2g10, ApcQ8

      (Suijkerbuijk et al., 2016)

      Scer\GAL4bun-GSG5961, Scer\GAL4GSG5966, Diap1UAS.cHa is a suppressor | RU486 conditional of decreased cell number | somatic clone | cell non-autonomous phenotype of Apc2g10, ApcQ8

      (Suijkerbuijk et al., 2016)

      Diap1UAS.cHa is a suppressor of increased cell death | somatic clone | cell non-autonomous phenotype of MycαTub84B.PBb

      (Levayer et al., 2015)

      Scer\GAL4αTub84B.PBb/Diap1UAS.cHa is a suppressor of increased cell death | somatic clone phenotype of Scer\GAL4FRT.Act5C, fweUASp.Lose-B.N.Tag:HA

      (Levayer et al., 2015)

      Diap1UAS.cHa, Scer\GAL4ap.PU is a suppressor of increased cell death | third instar larval stage phenotype of REGKK102083, Scer\GAL4ap.PU

      (Li et al., 2015)

      Diap1UAS.cHa/Scer\GAL4GMR.PFa is a suppressor of visible phenotype of DUBAIGD14040

      (Yang et al., 2014)

      Diap1UAS.cHa, Scer\GAL4Bx-MS1096 is a suppressor of visible phenotype of DaxxEY09290, Scer\GAL4Bx-MS1096

      (Hwang et al., 2013)

      Diap1UAS.cHa, Scer\GAL4CCAP.PP is a suppressor of abnormal neuroanatomy | adult stage phenotype of Scer\GAL4CCAP.PP, TBPHKK108354

      (Vanden Broeck et al., 2013)

      Diap1UAS.cHa, Scer\GAL4CCAP.PP is a suppressor of abnormal neuroanatomy | adult stage phenotype of Scer\GAL4CCAP.PP, TBPHUAS.Tag:FLAG

      (Vanden Broeck et al., 2013)

      Diap1UAS.cHa, Scer\GAL4CCAP.PP is a suppressor of visible phenotype of Scer\GAL4CCAP.PP, TBPHUAS.Tag:FLAG

      (Vanden Broeck et al., 2013)

      Diap1UAS.cHa, Scer\GAL4elav.PU is a suppressor of increased cell death | larval stage phenotype of Hsap\APPAβ42.UAS.cUa, Scer\GAL4elav.PU

      (Hong et al., 2012)

      Diap1UAS.cHa, Scer\GAL4elav.PU is a suppressor of lethal phenotype of Hsap\APPAβ42.UAS.cUa, Scer\GAL4elav.PU

      (Hong et al., 2012)

      Diap1UAS.cHa, Scer\GAL4elav.PU is a suppressor of abnormal locomotor behavior phenotype of Hsap\APPAβ42.UAS.cUa, Scer\GAL4elav.PU

      (Hong et al., 2012)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of increased cell death phenotype of Scer\GAL4GMR.PF, egrUAS.cIa

      (Ma et al., 2012)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of increased cell death phenotype of Scer\GAL4GMR.PF, nopoUAS.cUa

      (Ma et al., 2012)

      Diap1UAS.cHa, Scer\GAL4dpp.blk1 is a suppressor | partially of visible phenotype of HIV-1\VpuUAS.cLa, Scer\GAL4dpp.blk1

      (Marchal et al., 2012)

      Diap1UAS.cHa, Scer\GAL4nub-AC-62 is a suppressor of increased cell death | cell autonomous phenotype of Scer\GAL4nub-AC-62, hppyUAS.cMa

      (Resnik-Docampo and de Celis, 2011)

      Scer\GAL4ap-md544/Diap1UAS.cHa is a suppressor of visible phenotype of mir-9aJ22/mir-9aE39

      (Bejarano et al., 2010)

      Scer\GAL4mir-bft-Δ263a-G4/Diap1UAS.cHa is a suppressor of visible phenotype of mir-bftunspecified/mir-bftΔ263a-G4

      (Hilgers et al., 2010)

      Scer\GAL4ap-md544/Diap1UAS.cHa is a suppressor of increased cell death | dominant | third instar larval stage phenotype of apmd544

      (Portela et al., 2010)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of increased cell death phenotype of Scer\GAL4GMR.PF, egrUAS.cMa

      (Portela et al., 2010)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of visible phenotype of Scer\GAL4GMR.PF, egrUAS.cMa

      (Portela et al., 2010)

      Diap1UAS.cHa, Scer\GAL4nub-AC-62 is a suppressor of increased cell death phenotype of RYBPUAS.cBa, Scer\GAL4nub-AC-62

      (González and Busturia, 2009)

      Diap1UAS.cHa, Scer\GAL4unspecified is a suppressor of abnormal size phenotype of RYBPUAS.cBa, Scer\GAL4unspecified

      (González and Busturia, 2009)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of lethal | heat sensitive phenotype of Scer\GAL4GMR.PF, scnyGS13668

      (Ribaya et al., 2009)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of visible | heat sensitive phenotype of Scer\GAL4GMR.PF, scnyGS13668

      (Ribaya et al., 2009)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor | partially of abnormal neuroanatomy phenotype of Scer\GAL4GMR.PF, UbqnUAS.cGa

      (Ganguly et al., 2008)

      Diap1UAS.cHa, Scer\GAL4GMR.PU is a suppressor of visible phenotype of Scer\GAL4GMR.PU, Sirt1UAS.cGa

      (Griswold et al., 2008)

      Diap1UAS.cHa, Scer\GAL4GMR.PU is a suppressor of abnormal eye color phenotype of Scer\GAL4GMR.PU, Sirt1UAS.cGa

      (Griswold et al., 2008)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of increased cell death phenotype of Lkb1UAS.cLa, Scer\GAL4GMR.PF, SlnEP2245

      (Jang et al., 2008)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of visible phenotype of Atg1UAS.cSa, Scer\GAL4GMR.PF

      (Scott et al., 2007)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of partially lethal phenotype of Atg1UAS.cSa, Scer\GAL4GMR.PF

      (Scott et al., 2007)

      Scer\GAL4Tub.PU/Diap1UAS.cHa is a suppressor of increased cell death | somatic clone phenotype of Vps25N55

      (Herz et al., 2006)

      Scer\GAL4Tub.PU/Diap1UAS.cHa is a suppressor of increased cell death | somatic clone | larval stage phenotype of Vps25N55

      (Herz et al., 2006)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of increased cell death phenotype of Lkb1UAS.cLa, Scer\GAL4GMR.PF

      (Lee et al., 2006)

      Scer\GAL4Tub.PU/Diap1UAS.cHa is a suppressor of FlyBase_internaltransgene_features:cell lethal:cell lethal | somatic clone phenotype of ykiΔ.w

      (Thompson and Cohen, 2006)

      Diap1UAS.cHa, Scer\GAL4cv-c-C5 is a suppressor of increased cell death phenotype of Scer\GAL4cv-c-C5, hpoUAS.cUa

      (Udan et al., 2003)
      NOT Suppressor of
      Statement
      Reference

      Diap1UAS.cHa, Scer\GAL4en.PU is a non-suppressor of increased cell death | larval stage phenotype of Klp10AUAS.cYa, Scer\GAL4en.PU

      (Yang and Choi, 2021)

      Diap1UAS.cHa, Scer\GAL4elav.Switch.PO is a non-suppressor of abnormal behavior | RU486 conditional phenotype of Hsap\APP2xAPP.SP.UAS, Scer\GAL4elav.Switch.PO

      (Coelho et al., 2018)

      Diap1UAS.cHa, Scer\GAL4GMR.PS is a non-suppressor of visible | adult stage phenotype of Hsap\FUSUAS.cIa, Scer\GAL4GMR.PS

      (Lo Piccolo et al., 2017)

      Scer\GAL4Tub.PU/Diap1UAS.cHa is a non-suppressor | somatic clone of increased cell number | somatic clone phenotype of Apc2g10, ApcQ8

      (Suijkerbuijk et al., 2016)

      Diap1UAS.cHa, Scer\GAL4mirr-DE is a non-suppressor of increased cell death phenotype of Scer\GAL4mirr-DE, Ubr3KK100920

      (Huang et al., 2014)

      Diap1UAS.cHa, Scer\GAL4en.PU is a non-suppressor of increased cell death phenotype of Scer\GAL4en.PU, Ubr3KK100920

      (Huang et al., 2014)

      Scer\GAL4ey-OK107/Diap1UAS.cHa is a non-suppressor of abnormal neuroanatomy | somatic clone | adult stage | progressive phenotype of bskflp147E

      (Rallis et al., 2013)

      Scer\GAL4elav.PU/Diap1UAS.cHa is a non-suppressor of abnormal locomotor behavior | adult stage phenotype of Syx17LL06330/Df(3L)Exel8098

      (Takáts et al., 2013)

      Diap1UAS.cHa, Scer\GAL4nub-AC-62 is a non-suppressor of abnormal size phenotype of Scer\GAL4nub-AC-62, hppyUAS.cMa

      (Resnik-Docampo and de Celis, 2011)

      Diap1UAS.cHa, Scer\GAL4nub-AC-62 is a non-suppressor of decreased cell size phenotype of Scer\GAL4nub-AC-62, hppyUAS.cMa

      (Resnik-Docampo and de Celis, 2011)

      Scer\GAL4elav-C155, Top1JS, Diap1UAS.cHa is a non-suppressor of bang sensitive | recessive phenotype of eas2

      (Song et al., 2007)

      Diap1UAS.cHa, Scer\GAL4vg.PM is a non-suppressor of lethal | pupal stage phenotype of Scer\GAL4vg.PM, stwlUY823

      (Brun et al., 2006)

      Scer\GAL4Tub.PU/Diap1UAS.cHa is a non-suppressor of increased occurrence of cell division | somatic clone | cell non-autonomous | larval stage phenotype of Vps25N55

      (Herz et al., 2006)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a non-suppressor of visible phenotype of Pink1RNAi.UAS.cWa, Scer\GAL4GMR.PF

      (Wang et al., 2006)
      Other
      Phenotype Manifest In
      Suppressed by
      Enhancer of
      NOT Enhancer of
      Statement
      Reference

      Diap1UAS.cHa, Scer\GAL4GMR.PU is a non-enhancer of eye phenotype of Scer\GAL4GMR.PU, sraEY07182

      (Lee et al., 2016)
      Suppressor of
      Statement
      Reference

      Scer\GAL4Act.PU/Diap1UAS.cHa is a suppressor of eye-antennal disc | somatic clone phenotype of Ire1f02170

      (Zheng et al., 2023)

      Scer\GAL4Act.PU/Diap1UAS.cHa is a suppressor | partially of eye-antennal disc | somatic clone | larval stage phenotype of Ire1f02170, scrib1

      (Zheng et al., 2023)

      Scer\GAL4Act.PU/Diap1UAS.cHa is a suppressor | partially of eye-antennal disc | somatic clone phenotype of scrib1

      (Zheng et al., 2023)

      Diap1UAS.cHa, Scer\GAL4GMR.PFa is a suppressor of eye phenotype of Scer\GAL4GMR.PFa, Tom40UAS.Tag:FLAG,Tag:HA

      (Periasamy et al., 2022)

      Diap1UAS.cHa, Scer\GAL4Mef2.PR is a suppressor | partially of indirect flight muscle cell | pupal stage phenotype of Dlg5GD11943, Scer\GAL4Mef2.PR

      (Kaya-Çopur et al., 2021)

      Diap1UAS.cHa, Scer\GAL4Mef2.PR is a suppressor | partially of indirect flight muscle cell | pupal stage phenotype of Scer\GAL4Mef2.PR, ykiKK109756

      (Kaya-Çopur et al., 2021)

      Diap1UAS.cHa, Scer\GAL4ap.PU is a suppressor | partially of epithelial cell of wing disc | third instar larval stage phenotype of Ras85DV12.UAS, Scer\GAL4ap.PU

      (Soler Beatty et al., 2021)

      Scer\GAL4nub.PU/Diap1UAS.cHa is a suppressor | partially of wing disc | larval stage phenotype of RpS3Plac92, ykiB5

      (Wada et al., 2021)

      Scer\GAL4en.PU/Diap1UAS.cHa is a suppressor | partially of wing disc | larval stage phenotype of RpS3Plac92, ykiB5

      (Wada et al., 2021)

      Scer\GAL4nub.PU/Diap1UAS.cHa is a suppressor | partially of wing phenotype of RpS3Plac92, ykiB5

      (Wada et al., 2021)

      Scer\GAL4en.PU/Diap1UAS.cHa is a suppressor | partially of wing phenotype of RpS3Plac92, ykiB5

      (Wada et al., 2021)

      Diap1UAS.cHa, Scer\GAL4en.PU is a suppressor | partially of wing phenotype of Klp10AUAS.cYa, Scer\GAL4en.PU

      (Yang and Choi, 2021)

      Diap1UAS.cHa, Scer\GAL4en.PU is a suppressor of wing phenotype of PatroninGD11946, Scer\GAL4en.PU

      (Yang and Choi, 2021)

      Diap1UAS.cHa, Scer\GAL4en.PU is a suppressor of wing phenotype of PatroninKK100898, Scer\GAL4en.PU

      (Yang and Choi, 2021)

      Diap1UAS.cHa, Scer\GAL4GMR.PU is a suppressor | partially of eye phenotype of Scer\GAL4GMR.PU, SerTKK108310

      (Pham et al., 2020)

      Diap1UAS.cHa, Scer\GAL4GMR.PU is a suppressor | partially of ommatidium | adult stage phenotype of Scer\GAL4GMR.PU, SerTKK108310

      (Pham et al., 2020)

      Diap1UAS.cHa, Scer\GAL4GMR.PU is a suppressor | partially of interommatidial bristle | adult stage | absent phenotype of Scer\GAL4GMR.PU, SerTKK108310

      (Pham et al., 2020)

      Diap1UAS.cHa, Scer\GAL4GMR.PU is a suppressor | partially of eye disc | larval stage phenotype of Scer\GAL4GMR.PU, SerTKK108310

      (Pham et al., 2020)

      Diap1UAS.cHa, Scer\GAL4Burs.PL is a suppressor | partially of larval CCAP neuron | third instar larval stage phenotype of EcRB1-ΔC655.W650A.UAS, Scer\GAL4Burs.PL

      (Lee et al., 2019)

      Diap1UAS.cHa, Scer\GAL4elav.Switch.PO is a suppressor of adult brain | RU486 conditional phenotype of Hsap\APP2xAPP.SP.UAS, Scer\GAL4elav.Switch.PO

      (Coelho et al., 2018)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of eye disc phenotype of Hsap\APP2xAPP.SP.UAS, Scer\GAL4GMR.PF

      (Coelho et al., 2018)

      Diap1UAS.cHa, Scer\GAL4GMR.PFa is a suppressor of eye phenotype of DroncUAS.cSa, Scer\GAL4GMR.PFa

      (Sinenko, 2017)

      Diap1UAS.cHa, Scer\GAL4GMR.PFa is a suppressor of eye phenotype of DroncS130A.UAS.cSa, Scer\GAL4GMR.PFa

      (Sinenko, 2017)

      Diap1UAS.cHa, Scer\GAL4477 is a suppressor of larval multidendritic class IV neuron | third instar larval stage phenotype of Scer\GAL4477, nanosRNAi.UAS.WIZ

      (Bhogal et al., 2016)

      Diap1UAS.cHa, Scer\GAL4477 is a suppressor of dendrite | third instar larval stage phenotype of Scer\GAL4477, nanosRNAi.UAS.WIZ

      (Bhogal et al., 2016)

      Diap1UAS.cHa, Scer\GAL4477 is a suppressor of larval multidendritic class IV neuron | third instar larval stage phenotype of Scer\GAL4477, pumHMS01685

      (Bhogal et al., 2016)

      Diap1UAS.cHa, Scer\GAL4477 is a suppressor of dendrite | third instar larval stage phenotype of Scer\GAL4477, pumHMS01685

      (Bhogal et al., 2016)

      Scer\GAL4bun-GSG5961, Scer\GAL4GSG5966, Diap1UAS.cHa is a suppressor | RU486 conditional of intestinal stem cell of posterior adult midgut epithelium | somatic clone phenotype of Apc2g10, ApcQ8

      (Suijkerbuijk et al., 2016)

      Scer\GAL4bun-GSG5961, Scer\GAL4GSG5966, Diap1UAS.cHa is a suppressor | RU486 conditional of intestinal stem cell of posterior adult midgut epithelium | somatic clone | cell non-autonomous phenotype of Apc2g10, ApcQ8

      (Suijkerbuijk et al., 2016)

      Scer\GAL4αTub84B.PBb/Diap1UAS.cHa is a suppressor of mesothoracic tergum | somatic clone | cell non-autonomous phenotype of MycαTub84B.PBb

      (Levayer et al., 2015)

      Scer\GAL4αTub84B.PBb/Diap1UAS.cHa is a suppressor of mesothoracic tergum | somatic clone phenotype of Scer\GAL4FRT.Act5C, fweUASp.Lose-B.N.Tag:HA

      (Levayer et al., 2015)

      Diap1UAS.cHa, Scer\GAL4ap.PU is a suppressor of wing disc | third instar larval stage phenotype of REGKK102083, Scer\GAL4ap.PU

      (Li et al., 2015)

      Scer\GAL469B/Diap1UAS.cHa is a suppressor | partially of wing disc | third instar larval stage phenotype of pcm14

      (Waldron et al., 2015)

      Diap1UAS.cHa/Scer\GAL4GMR.PFa is a suppressor of eye phenotype of DUBAIGD14040

      (Yang et al., 2014)

      Diap1UAS.cHa, Scer\GAL4Bx-MS1096 is a suppressor of wing phenotype of DaxxEY09290, Scer\GAL4Bx-MS1096

      (Hwang et al., 2013)

      Diap1UAS.cHa, Scer\GAL4CCAP.PP is a suppressor of peptidergic neuron phenotype of Scer\GAL4CCAP.PP, TBPHUAS.Tag:FLAG

      (Vanden Broeck et al., 2013)

      Diap1UAS.cHa, Scer\GAL4CCAP.PP is a suppressor of wing phenotype of Scer\GAL4CCAP.PP, TBPHUAS.Tag:FLAG

      (Vanden Broeck et al., 2013)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of eye phenotype of Scer\GAL4GMR.PF, nopoUAS.cUa

      (Ma et al., 2012)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of eye phenotype of Scer\GAL4GMR.PF, egrUAS.cIa

      (Ma et al., 2012, Mallik and Lakhotia, 2009)

      Diap1UAS.cHa, Scer\GAL4dpp.blk1 is a suppressor | partially of wing phenotype of HIV-1\VpuUAS.cLa, Scer\GAL4dpp.blk1

      (Marchal et al., 2012)

      Scer\GAL4ap-md544/Diap1UAS.cHa is a suppressor of wing phenotype of mir-9aJ22/mir-9aE39

      (Bejarano et al., 2010)

      Scer\GAL4mir-bft-Δ263a-G4/Diap1UAS.cHa is a suppressor of interommatidial bristle phenotype of mir-bftunspecified/mir-bftΔ263a-G4

      (Hilgers et al., 2010)

      Scer\GAL4ap-md544/Diap1UAS.cHa is a suppressor of wing disc | third instar larval stage phenotype of apmd544

      (Portela et al., 2010)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of eye phenotype of Scer\GAL4GMR.PF, egrUAS.cMa

      (Portela et al., 2010)

      Diap1UAS.cHa, Scer\GAL4nub-AC-62 is a suppressor of wing disc | third instar larval stage phenotype of RYBPUAS.cBa, Scer\GAL4nub-AC-62

      (González and Busturia, 2009)

      Diap1UAS.cHa, Scer\GAL4unspecified is a suppressor of wing phenotype of RYBPUAS.cBa, Scer\GAL4unspecified

      (González and Busturia, 2009)

      Scer\GAL4GMR.PF/Diap1UAS.cHa is a suppressor of eye phenotype of rprGMR.PW

      (Mallik and Lakhotia, 2009)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of eye | heat sensitive phenotype of Scer\GAL4GMR.PF, scnyGS13668

      (Ribaya et al., 2009)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor | partially of eye phenotype of Scer\GAL4GMR.PF, UbqnUAS.cGa

      (Ganguly et al., 2008)

      Diap1UAS.cHa, Scer\GAL4GMR.PU is a suppressor of eye phenotype of Scer\GAL4GMR.PU, Sirt1UAS.cGa

      (Griswold et al., 2008)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of eye phenotype of Lkb1UAS.cLa, Scer\GAL4GMR.PF

      (Jang et al., 2008)

      Diap1UAS.cHa, Scer\GAL4slbo.2.6 is a suppressor | partially of border follicle cell phenotype of PvrDN.UASp, Scer\GAL4slbo.2.6, hepAct.UAS

      (Mathieu et al., 2007)

      Diap1UAS.cHa, Scer\GAL4GMR.PF is a suppressor of eye phenotype of Atg1UAS.cSa, Scer\GAL4GMR.PF

      (Scott et al., 2007)

      Scer\GAL4αTub84B.PL/Diap1UAS.cHa is a suppressor | partially of wing disc | somatic clone phenotype of cpa107E

      (Janody and Treisman, 2006)

      Diap1UAS.cHa, Scer\GAL4cv-c-C5 is a suppressor of wing phenotype of Scer\GAL4cv-c-C5, hpoUAS.cUa

      (Udan et al., 2003)

      Diap1UAS.cHa, Scer\GAL4cv-c-C5 is a suppressor of adult head phenotype of Scer\GAL4cv-c-C5, hpoUAS.cUa

      (Udan et al., 2003)
      NOT Suppressor of
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The photoreceptor depigmentation phenotype characteristic for adult flies expressing DroncUAS.cSa under the control of Scer\GAL4GMR.PFa is fully suppressed by co-expression of Diap1Scer\UAS.cHa.

      (Sinenko, 2017)

      The dendritic field coverage defects and loss of terminal branches observed in class IV dendritic arborizing neurons of third instar larvae expressing nosdsRNA.Scer\UAS.WIZ under the control of Scer\GAL4477 is suppressed by co-expression of Diap1Scer\UAS.cHa.

      The dendritic field coverage and branching defects observed in class IV dendritic arborizing neurons of third instar larvae expressing pumHMS01685 under the control of Scer\GAL4477 is suppressed by co-expression of Diap1Scer\UAS.cHa.

      (Bhogal et al., 2016)

      The mild rough-eye phenotype characteristic for flies expressing sraEY07182 under the control of Scer\GAL4GMR.PU is suppressed by co-expression of Diap1Scer\UAS.cHa.

      (Lee et al., 2016)

      Expression of Diap1Scer\UAS.cHa under the control of Scer\GAL4bun-GSG5961 and Scer\GAL4GSG5966 (along with RU486 to induce expression via the GeneSwitch system) in the gut fully restores growth of wild type clones in the presence of ApcQ8/ApcQ8, Apc2g10/Apc2g10 mutant clones in the posterior midgut, and suppresses the growth of ApcQ8/ApcQ8, Apc2g10/Apc2g10 mutant clones; however, ApcQ8/ApcQ8, Apc2g10/Apc2g10 mutant clones expressing Diap1Scer\UAS.cHa under the control of Scer\GAL4tub.PU do not have suppressed growth.

      (Suijkerbuijk et al., 2016)

      Inhibition of apoptosis using (Diap1Scer\UAS.cHa under the control of Scer\GAL4αTub84B.PBb) suppresses the contact-dependent delamination seen in wild type 'loser' cells when cell competition is induced in the pupal notum through generation of wild type clones in super-competitive MycαTub84B.PBb-expressing tissue. Inhibiting apoptosis does not suppress the increase in clone splitting (used as a readout for winner-loser cell mixing) or reduction in clone compactness seen in wild type 'loser' clones in the wing disc.

      (Levayer et al., 2015)

      The increased level of cell death (detected by Casp3 antibody staining) observed in wing discs of third instar larvae expressing REGKK102083 RNAi under the control of Scer\GAL4ap.PU is suppressed by co-expression of Diap1Scer\UAS.cHa.

      (Li et al., 2015)

      The reduced size of the third larval instar imaginal wing disc characteristic for pcm14 homozygotes is strongly rescued by expression of Diap1Scer\UAS.cHa under the control of Scer\GAL469B (using tub-Gal80[ts] to limit the time of expression) in the mutant background. The resulting disc size is intermediate between that of pcm14 alone and that of Diap1Scer\UAS.cHa-expressing discs (which are bigger than wild-type) and smaller than wild-type.

      (Waldron et al., 2015)

      Co-expression of thScer\UAS.cHa suppresses the eye defects caused by expression of DUBAIGD14040 under the control of Scer\GAL4GMR.PFa.

      (Yang et al., 2014)

      Expression of thScer\UAS.cHa enhances the eye phenotype seen when Sin3AKK100700 is expressed under the control of Scer\GAL4GMR.PF; approximately a third of all adults examined show enhanced overgrowth and secondary tumors that grow stably at distant sites.

      (Das et al., 2013)

      Co-expression of thScer\UAS.cHa almost completely suppresses the reduction in wing size caused by expression of DLPEY09290 under the control of Scer\GAL4Bx-MS1096.

      (Hwang et al., 2013)

      Expression of two copies of thScer\UAS.cHa under the control of Scer\GAL4ey-OK107 fails to suppress the axon degeneration seen in bskflp147E mutant mushroom body neuron clones.

      (Rallis et al., 2013)

      Expression of thScer\UAS.cHa under the control of Scer\GAL4elav.PU does not rescue the climbing defects of Syx17LL06330/Df(3L)Exel8098 flies.

      (Takáts et al., 2013)

      Expression of Diap1Scer\UAS.cHa suppresses the reduction in CCAP/bursicon neuron number seen in newly eclosed flies expressing TBPHKK108354 under the control of Scer\GAL4CCAP.PP.

      Expression of Diap1Scer\UAS.cHa suppresses the reduction in CCAP/bursicon neuron number seen in newly eclosed flies expressing TBPHScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4CCAP.PP. The wing inflation defects are also rescued.

      (Vanden Broeck et al., 2013)

      Co-expression of thScer\UAS.cHa strongly suppresses the small, rough eye phenotype found upon expression of nopoScer\UAS.cUa under the control of Scer\GAL4GMR.PF.

      Expression of thScer\UAS.cHa suppresses the small eye phenotype in flies expressing egrScer\UAS.cIa under the control of Scer\GAL4GMR.PF.

      (Ma et al., 2012)

      Co-expression of thScer\UAS.cHa suppresses the increased apoptosis and increased fraction of mitotic cells phenotypes seen in Scer\GAL4nub-AC-62, hppyScer\UAS.cMa discs.

      (Resnik-Docampo and de Celis, 2011)

      Expression of thScer\UAS.cHa under the control of Scer\GAL4ap-md544 completely rescues the wing notching phenotype of mir-9aJ22/mir-9aE39 animals.

      (Bejarano et al., 2010)

      Expression of thScer\UAS.cHa under the control of Scer\GAL4bft-Δ263a-G4 suppresses the loss of interommatidial bristles which is seen in bftΔ263a-G4/bftunspecified flies.

      (Hilgers et al., 2010)

      Overexpression of thScer\UAS.cHa under the control of Scer\GAL4ap-md544 suppresses the increased apoptosis in apmd544/+ wing discs.

      Co-expression of thScer\UAS.cHa partially suppresses the eye-size defect resulting from the ectopic expression of egrScer\UAS.cMa using Scer\GAL4GMR.PF.

      (Portela et al., 2010)

      The increased apoptosis seen in Scer\GAL4nub-AC-62 RYBPScer\UAS.cBa wing discs is completely inhibited by coexpression of thScer\UAS.cHa.

      The small wing size seen in Scer\GAL4unspecified RYBPScer\UAS.cBa wings is rescued by coexpression of thScer\UAS.cHa.

      (González and Busturia, 2009)

      Expression of thScer\UAS.cHa under the control of Scer\GAL4tub in clones in the wing disc does not allow the recovery of large homozygous Df(2L)32FP-5 clones in the notum region.

      (Grieder et al., 2009)

      Expression of thScer\UAS.cHa using Scer\GAL4GMR.PF rescues the rprGMR.PW small eye phenotype.

      Co-expression of thScer\UAS.cHa suppresses the eye phenotype of Scer\GAL4GMR.PF, egrScer\UAS.cIa flies.

      (Mallik and Lakhotia, 2009)

      Co-expression of thScer\UAS.cHa completely suppresses the lethality caused by expression of scnyGS13668 under the control of Scer\GAL4GMR.PF at 25[o]C, and partially suppresses the mutant eye phenotype.

      (Ribaya et al., 2009)

      Scer\GAL4tub- or Scer\GAL4Act5C.PI-driven expression of thScer\UAS.cHa does not suppress the loss of follicle stem cells in CycEWX mutant clones.

      (Wang and Kalderon, 2009)

      Co-expression of thScer\UAS.cHa results in a marked rescue of the degeneration phenotype seen in the eyes of flies expressing UbqnScer\UAS.cGa under the control of Scer\GAL4GMR.PF.

      (Ganguly et al., 2008)

      Co-expression of thScer\UAS.cHa suppresses the defective eye phenotype caused by expression of Sir2Scer\UAS.cGa under the control of Scer\GAL4GMR.PU.

      (Griswold et al., 2008)

      Co-expression of thScer\UAS.cHa with both lkb1Scer\UAS.cLa and SlnEP2245 considerably suppresses the apoptotic cell death induced by lkb1Scer\UAS.cLa and SlnEP2245 co-expression in the eye (all under the control of Scer\GAL4GMR.PF).

      (Jang et al., 2008)

      The border follicle cell migration defects that are seen in flies co-expressing both PvrDN.Scer\UAS and hepAct.Scer\UAS under the control of Scer\GAL4slbo.2.6 are partially suppressed by the co-expression of thScer\UAS.cHa.

      (Mathieu et al., 2007)

      The partial lethality and reduced eye size caused by expression of Atg1Scer\UAS.cSa under the control of Scer\GAL4GMR.PF is rescued by co-expression of thScer\UAS.cHa.

      (Scott et al., 2007)

      The partial suppression of the bang sensitive phenotype and decreased seizure threshold* of eas2 homozygotes is itself suppressed by thScer\UAS.cHa, Scer\GAL4elav-C155.

      (Song et al., 2007)

      Blocking cell death, through expression of thScer\UAS.cHa in Vps25N55 mutant clones does not affect proliferation or Stat92E activity.

      Vps25N55/thScer\UAS.cHa mosaics exhibit non-autonomous cell proliferation. Eye-antennal discs of Vps25N55/thScer\UAS.cHa mosaics are extremely overgrown and can be 5-times as large as wild-type discs. Cell death is completely blocked in Vps25N55/thScer\UAS.cHa mosaics. Vps25N55/thScer\UAS.cHa clones occupy a large fraction of the eye discs, suggesting that these clones have no intrinsic growth disadvantage over wild-type tissue if cell death is blocked. Thus, inhibiting cell death in Vps25N55 clones can give rise to an even stronger overgrowth phenotype.

      (Herz et al., 2006)

      lkb1Scer\UAS.cLa-induced apoptosis is completely suppressed by expression of thScer\UAS.cHa, both under the control of Scer\GAL4GMR.PF. Interestingly, even when lkb1-indueced apoptosis is completely blocked by th, the BrdU and His3 staining patterns do not deviate from the wild-type patterns.

      (Lee et al., 2006)

      Coexpression of thScer\UAS.cHa and CycEScer\UAS.cRa in the developing eye, under the control of Scer\GAL4GMR.PF, results in the generation of many small ommatidial cells.

      The extra ommatidial cell phenotype seen in Scer\GAL4GMR.PF>banEP3622 pupal retinae is not enhanced by thScer\UAS.cHa.

      Coexpression of banEP3622, CycEScer\UAS.cRa and thScer\UAS.cHa, under the control of Scer\GAL4GMR.PF, causes a large increase in interommatidial, cone and photoreceptor cells.

      (Nolo et al., 2006)

      Coexpression of thScer\UAS.cHa and hpoScer\UAS.cUa, under the control of Scer\GAL4ptc-559.1, in wing discs leads to a folding of the epithelium in the ptc expression region.

      Expression of thScer\UAS.cHa, under the control of Scer\GAL4tub, in ykiΔ.w mutant clones generated in the wing disc, rescues the survival of these clones but results in clones that are smaller than those generated in wild-type controls.

      Clones in the wing disc that express hpoScer\UAS.cUa, under the control of Scer\GAL4tub, (rescued for apoptosis by expression of thScer\UAS.cHa) cause nuclei to move basally, inducing cells to change shape and causing a basally-directed folding of the epithelium.

      (Thompson and Cohen, 2006)

      The small head and wing phenotypes, caused by an increase in apoptosis, seen in flies that express hpoScer\UAS.cUa under the control of Scer\GAL4C5 is partially rescued by coexpression of thScer\UAS.cHa.

      (Udan et al., 2003)
      Xenogenetic Interactions
      Statement
      Reference

      The eye degeneration and the associated rough eye appearance, ommatidial fusion and pigmentation loss characteristic for adult flies expressing Hsap\FUSScer\UAS.cIa under the control of Scer\GAL4GMR.PS cannot be rescued by co-expression of Diap1Scer\UAS.cHa.

      (Lo Piccolo et al., 2017)

      Co-expression of thScer\UAS.cHa partially suppresses the wing defects caused by expression of HIV-1\VpuScer\UAS.cLa under the control of Scer\GAL4dpp.blk1.

      (Marchal et al., 2012)
      Complementation and Rescue Data
      Rescues

      Scer\GAL434B/Diap1UAS.cHa rescues Diap1RNAi.UAS

      (Choi et al., 2006)

      Scer\GAL4GMR.PF/Diap1UAS.cHa rescues Diap1RNAi.UAS.cLa

      (Leulier et al., 2006)
      Partially rescues

      Scer\GAL4T80/Diap1UAS.cHa partially rescues Diap1th-1

      (Cullen and McCall, 2004)
      Comments

      Expression of thScer\UAS.cHa in the salivary glands under the control of Scer\GAL434B rescues programmed cell death in salivary glands expressing thdsRNA.Scer\UAS.

      (Choi et al., 2006)

      The eye phenotype in animals expressing thdsRNA.Scer\UAS.cLb under the control of Scer\GAL4GMR.PF is fully rescued by co-expression of thScer\UAS.cHa.

      (Leulier et al., 2006)

      When thScer\UAS.cHa is driven by Scer\GAL4T80 is th1 animals, a partial rescue of the arista phenotype is seen. Rescued aristae are very short and located only along the posterior of the arista.

      (Cullen and McCall, 2004)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Diap1Scer\UAS.cHa
      Diap1UAS.cHa
      thScer\UAS.cHa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Hay
      (Lohmann et al., 2002)
      Secondary FlyBase IDs
        References (110)