eye disc & S phase, with Scer\GAL4GMR.PS
Hsap\TP53Scer\UAS.cYa results in a dosage dependent eye degeneration phenotype.
Flies expressing one copy of Hsap\TP53Scer\UAS.cYa under the control of one copy of Scer\GAL4GMR.PS have severely abnormal eyes which are very rough in appearance. The ommatidia lack the regular hexagonal shape seen in wild-type flies and either additional or missing bristles are apparent. The phenotype is more severe if the flies are carrying two copies of Hsap\TP53Scer\UAS.cYa; many ommatidia appear fused, rhabdomeres with irregular shapes are seen and many ommatidia lack pigment cells. In eye discs expressing one copy of Hsap\TP53Scer\UAS.cYa under the control of one copy of Scer\GAL4GMR.PS incorporation of BrdU in the S phase zone corresponding to the second mitotic wave is reduced compared to wild type. In eye discs expressing two copies of Hsap\TP53Scer\UAS.cYa under the control of one copy of Scer\GAL4GMR.PS the S phase zone corresponding to the second mitotic wave is almost abolished. There is a significant increase in cell death posterior to the furrow in these eye discs. Extensive cell death is only seen in the very posterior of the disc.
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(2L)S3
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(2L)A246
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(2L)TW137
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(1)C246
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(2L)VA12
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(2L)pr-A16
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(2L)Sd77
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(2R)M41A4
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(2R)CA53
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(2R)E3363
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(2R)en28
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(2R)en-SFX31
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(2R)Pu-D17
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(2R)or-BR6
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(1)KA9
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(3L)vin2
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(3L)VW3
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(3R)9A99
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(3R)p-XT103
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(3R)ry615
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(3R)e-N19
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(4)M101-62f
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, enhanceable by Df(2L)ast2
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, non-enhanceable by Df(3L)W10
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, non-enhanceable by Df(3L)Cat
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, non-enhanceable by Df(3L)W4
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, non-enhanceable by Df(2R)B5
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, non-enhanceable by dap4
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, non-enhanceable by dap04454
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, suppressible by BacA\p35GMR.PH
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, suppressible by Df(2R)cn9
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, suppressible by Df(2R)ST1
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, suppressible by Df(3L)pbl-X1
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, suppressible by Df(3L)BK10
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, suppressible by Df(3R)Tpl10
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, suppressible by Df(3R)crb87-5
Hsap\TP53UAS.cYa has visible phenotype, non-suppressible by TER94[+]/TER9426-8
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, non-suppressible by Df(3L)W10
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, non-suppressible by Df(3L)Cat
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, non-suppressible by Df(3L)W4
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, non-suppressible by Df(2R)B5
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, non-suppressible by dap4
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has visible phenotype, non-suppressible by dap04454
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(1)C246
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(1)C246
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(2L)S3
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(2L)A246
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(2L)A246
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(2L)TW137
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(2L)TW137
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(2L)VA12
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(2L)VA12
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(2L)pr-A16
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(2L)pr-A16
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(2L)Sd77
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(2L)Sd77
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(2R)M41A4
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(2R)M41A4
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(1)KA9
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(2R)CA53
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(2R)CA53
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(2R)E3363
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(2R)E3363
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(2R)en28
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(2R)en28
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(2R)en-SFX31
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(1)KA9
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(2R)en-SFX31
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(2R)Pu-D17
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(2R)Pu-D17
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(2R)or-BR6
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(2R)or-BR6
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(3L)vin2
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(3L)vin2
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(3L)VW3
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(3L)VW3
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(3R)9A99
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(3R)9A99
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(3R)p-XT103
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(3R)p-XT103
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(2L)ast2
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(3R)ry615
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(3R)ry615
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(3R)e-N19
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(3R)e-N19
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(4)M101-62f
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(4)M101-62f
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, enhanceable by Df(2L)ast2
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, enhanceable by Df(2L)S3
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, suppressible by Df(2R)cn9
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, suppressible by Df(2R)cn9
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, suppressible by Df(2R)ST1
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, suppressible by Df(2R)ST1
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, suppressible by Df(3L)pbl-X1
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, suppressible by Df(3L)pbl-X1
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, suppressible by Df(3L)BK10
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, suppressible by Df(3L)BK10
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, suppressible by Df(3R)Tpl10
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, suppressible by Df(3R)Tpl10
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, suppressible by Df(3R)crb87-5
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, suppressible by Df(3R)crb87-5
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has eye phenotype, suppressible by BacA\p35GMR.PH
Hsap\TP53UAS.cYa, Scer\GAL4GMR.PS has ommatidium phenotype, suppressible by BacA\p35GMR.PH
Hsap\TP53UAS.cYa has eye phenotype, non-suppressible by TER94[+]/TER9426-8
BacA\p35GMR.PH is a strong suppressor of the rough eye phenotype caused by expression of Hsap\TP53Scer\UAS.cYa under the control of Scer\GAL4GMR.PS.