FlyBase Allele Report: Dmel\noi[+t3.6]

General Information

Symbol

Dmel\noi^+t3.6

Species

D. melanogaster

Name

FlyBase ID

FBal0088769

Feature type

allele

Associated gene

Dmel\noi

Associated Insertion(s)

Carried in Construct

P{noi⁺3.6}

Key Links

Genomic Maps

JBrowse

Transgenic product class

genomic_DNA

(Meyer et al., 1998)

wild_type

(Meyer et al., 1998)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

genomic_DNA

(Meyer et al., 1998)

wild_type

(Meyer et al., 1998)

Mutagen

in vitro construct

(Meyer et al., 1998)

Progenitor genotype

Carried in construct

P{noi⁺3.6}

Cytology

Description

3.6kb PstI genomic fragment containing noi open reading frame and flanking sequence and part of the 5' end of Vha26.

(Meyer et al., 1998)

Allele components

Component

Use(s)

Regulatory region(s)

noi

Encoded product / tool

noi

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

rescue_region

3R:5,589,153..5,592,735 [-]

Linked to:

PstI-PstI restriction fragment

Comment:

Position of restriction fragment on reference sequence inferred by FlyBase curator

(Meyer et al., 1998)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

wild-type

(Meyer et al., 1998)

Phenotype Manifest In

Detailed Description

Statement

Reference

noi^+t3.6 can rescue all aspects of the noi mutant phenotype for noi^A, Df(3R)noi-B and noi^D, except the homozygous lethality.

(Meyer et al., 1998)

noi^+t3.6 can rescue all aspects of the noi mutant phenotype for noi^A, noi^B and noi^D, except the homozygous lethality.

(Meyer et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Df(3R)noi-B, noi^A, noi^+t3.6 is a non-enhancer of viable phenotype of mad2^G6595

(Buffin et al., 2007)

Df(3R)noi-B, noi^A, noi^+t3.6 is a non-enhancer of fertile phenotype of mad2^G6595

(Buffin et al., 2007)

Df(3R)noi-B, noi^A, noi^+t3.6 is a non-enhancer of abnormal cell cycle phenotype of mad2^G6595

(Buffin et al., 2007)

Df(3R)noi-B, noi^A, noi^+t3.6 is a non-enhancer of abnormal mitotic cell cycle phenotype of mad2^G6595

(Buffin et al., 2007)

NOT Suppressor of

Statement

Reference

Df(3R)noi-B, noi^A, noi^+t3.6 is a non-suppressor of viable phenotype of mad2^G6595

(Buffin et al., 2007)

Df(3R)noi-B, noi^A, noi^+t3.6 is a non-suppressor of fertile phenotype of mad2^G6595

(Buffin et al., 2007)

Df(3R)noi-B, noi^A, noi^+t3.6 is a non-suppressor of abnormal cell cycle phenotype of mad2^G6595

(Buffin et al., 2007)

Df(3R)noi-B, noi^A, noi^+t3.6 is a non-suppressor of abnormal mitotic cell cycle phenotype of mad2^G6595

(Buffin et al., 2007)

Other

Statement

Reference

Sxl^M12, noi^+t3.6 has viable phenotype

(Cline et al., 1999)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

noi^+t3.6 is a non-enhancer of sex comb phenotype of Sxl^Mf1, snf^+t5.5

(Cline et al., 1999)

NOT Suppressor of

Statement

Reference

noi^+t3.6 is a non-suppressor of sex comb phenotype of Sxl^Mf1, snf^+t5.5

(Cline et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

mad2^G6595 rev7 double mutants (where the rev7 mutant is constructed as noi^+t3.6; noi^A/Df(3R)noi-B) are viable and show no greater aneuploidy than mad2^G6595 single mutants.

(Buffin et al., 2007)

The addition of noi^+t3.6 to Sxl^Mf1/Y males with two copies of P{snf⁺,dhd⁺} has no significant effect on the foreleg feminisation phenotype seen in those flies. The addition of noi^+t3.6 essentially has no deleterious effects on Sxl^M12/Y males.

(Cline et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

noi^+t3.6 rescues noi¹

(Meyer et al., 1998)

noi^+t3.6 rescues noi²

(Meyer et al., 1998)

Fails to rescue

noi^+t3.6 fails to rescue noi^A

(Meyer et al., 1998)

noi^+t3.6 fails to rescue noi^C

(Meyer et al., 1998)

noi^+t3.6 fails to rescue Df(3R)noi-B

(Meyer et al., 1998)

noi^+t3.6 fails to rescue noi^D

(Meyer et al., 1998)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

noi^+t3.6

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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