FlyBase Allele Report: Dmel\noi[A]

General Information

Symbol

Dmel\noi^A

Species

D. melanogaster

Name

FlyBase ID

FBal0088763

Feature type

allele

Associated gene

Dmel\noi

Associated Insertion(s)

Carried in Construct

Also Known As

Df(3R)noi-A

Key Links

Allele class

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Meyer et al., 1998)

Progenitor genotype

noi²

(Meyer et al., 1998)

noi¹

(Meyer et al., 1998)

Cytology

Description

Deletion of the entire P{lacW} insertion and entire noi genomic sequences.

(Meyer et al., 1998)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die during embryonic stage | recessive

(Meyer et al., 1998)

some die during embryonic stage | recessive

(Meyer et al., 1998)

Phenotype Manifest In

Detailed Description

Statement

Reference

Embryonic development of transheterozygotes with noi^C is completely normal but the embryos fail to hatch. noi^+t3.6 cannot rescue the homozygous lethality.

(Meyer et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Df(3R)noi-B, noi^A, noi^+t3.6 is a non-enhancer of viable phenotype of mad2^G6595

(Buffin et al., 2007)

Df(3R)noi-B, noi^A, noi^+t3.6 is a non-enhancer of fertile phenotype of mad2^G6595

(Buffin et al., 2007)

Df(3R)noi-B, noi^A, noi^+t3.6 is a non-enhancer of abnormal cell cycle phenotype of mad2^G6595

(Buffin et al., 2007)

Df(3R)noi-B, noi^A, noi^+t3.6 is a non-enhancer of abnormal mitotic cell cycle phenotype of mad2^G6595

(Buffin et al., 2007)

NOT Suppressor of

Statement

Reference

Df(3R)noi-B, noi^A, noi^+t3.6 is a non-suppressor of viable phenotype of mad2^G6595

(Buffin et al., 2007)

Df(3R)noi-B, noi^A, noi^+t3.6 is a non-suppressor of fertile phenotype of mad2^G6595

(Buffin et al., 2007)

Df(3R)noi-B, noi^A, noi^+t3.6 is a non-suppressor of abnormal cell cycle phenotype of mad2^G6595

(Buffin et al., 2007)

Df(3R)noi-B, noi^A, noi^+t3.6 is a non-suppressor of abnormal mitotic cell cycle phenotype of mad2^G6595

(Buffin et al., 2007)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

mad2^G6595 rev7 double mutants (where the rev7 mutant is constructed as noi^+t3.6; noi^A/Df(3R)noi-B) are viable and show no greater aneuploidy than mad2^G6595 single mutants.

(Buffin et al., 2007)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Not rescued by

noi^A is not rescued by noi^+t3.6

(Meyer et al., 1998)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

"noi¹" was stated as tentative. "noi²" was stated as tentative. It is not known if the homozygous lethality is due to deletion of another essential gene or if the chromosome bears another lethal mutation elsewhere.

(Meyer et al., 1998)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Df(3R)noi-A

(Buffin et al., 2007, Meyer et al., 1998)

noi^A

noiA

(Buffin et al., 2007)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

Open Close