FlyBase Allele Report: Dmel\arm[UAS.cWa]

General Information

Symbol

Dmel\arm^UAS.cWa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of White

FlyBase ID

FBal0086716

Feature type

allele

Associated gene

Dmel\arm

Associated Insertion(s)

Carried in Construct

P{UAS-arm.W}

Also Known As

UAS-arm

Key Links

Transgenic product class

cDNA

(White et al., 1998)

wild_type

(White et al., 1998)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(White et al., 1998)

wild_type

(White et al., 1998)

Mutagen

in vitro construct

(White et al., 1998)

Progenitor genotype

Carried in construct

P{UAS-arm.W}

Cytology

Description

A KpnI/NotI arm cDNA fragment is expressed under the control of UASt regulatory sequences.

(White et al., 1998)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

arm

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^Bx-MS1096

(White et al., 1998)

visible, with Scer\GAL4^en.PU

(Mathew et al., 2011)

visible, with Scer\GAL4^en-e16E

(Greaves et al., 1999)

visible, with Scer\GAL4^GMR.PF

(Greaves et al., 1999)

Phenotype Manifest In

embryonic/first instar larval cuticle | germline clone, with Scer\GAL4^arm.PS

(White et al., 1998)

eye, with Scer\GAL4^GMR.PF

(Greaves et al., 1999)

interommatidial bristle, with Scer\GAL4^GMR.PF

(Greaves et al., 1999)

ommatidium, with Scer\GAL4^GMR.PF

(Greaves et al., 1999)

ventral denticle belt | germline clone, with Scer\GAL4^arm.PS

(White et al., 1998)

wing, with Scer\GAL4^Bx-MS1096

(White et al., 1998)

wing | posterior, with Scer\GAL4^en-e16E

(Greaves et al., 1999)

wing margin bristle | ectopic, with Scer\GAL4^bbg-C96

(Marygold and Vincent, 2003)

wing margin bristle | ectopic, with Scer\GAL4^Bx-MS1096

(White et al., 1998)

wing margin bristle | ectopic, with Scer\GAL4^en.PU

(Mathew et al., 2011)

wing margin bristle | ectopic, with Scer\GAL4^en-e16E

(Marygold and Vincent, 2003)

wing sensillum | ectopic, with Scer\GAL4^en-e16E

(Greaves et al., 1999)

wing vein | ectopic, with Scer\GAL4^Bx-MS1096

(White et al., 1998)

wing vein | ectopic, with Scer\GAL4^en-e16E

(Greaves et al., 1999)

Detailed Description

Statement

Reference

Expression of arm^Scer\UAS.cWa under the control of Scer\GAL4^nub.PU does not have a wing margin bristle phenotype in adult flies.

(Banerjee et al., 2017)

Expression of arm^Scer\UAS.cWa under the control of Scer\GAL4^en.PU results in ectopic bristles on the wing margin.

(Mathew et al., 2011)

When arm^Scer\UAS.cWa is driven by Scer\GAL4^en-e16E ectopic wing margin bristles are see in the wing blade.

(Marygold and Vincent, 2003)

Expression of arm^Scer\UAS.cWa under the control of Scer\GAL4^en-e16E induces excess veins and bristles in the posterior wing blade. The extra veins concentrate around the posterior crossvein. Expression of arm^Scer\UAS.cWa under the control of Scer\GAL4^GMR.PF results in rough eyes and the loss of interommatidial bristles.

(Greaves et al., 1999)

Expression of arm^Scer\UAS.cWa under the control of Scer\GAL4^arm.PS in arm²/+ embryos derived from homozygous arm² female germline clones leads to a slight loss of denticles. Overexpression of arm^Scer\UAS.cWa under the control of Scer\GAL4^Bx-MS1096 results in ectopic wing vein formation and the formation of margin bristles in the wing blade.

(White et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^en.PU, arm^UAS.cWa has visible phenotype, enhanceable by Traf4[+]/Traf4³

(Mathew et al., 2011)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by sgg^M11/sgg[+]

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has visible phenotype, enhanceable by sgg^M11

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by nkd²

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by shg¹

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by ft^G-rv

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by ds⁵⁵

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by crb^8F105

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by sdt^EH681

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by dlg1¹⁴

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by Egfr^f3

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by rho¹⁰

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by aos⁰⁰⁶

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by CycA³

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by Df(3L)pbl-X1

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has visible phenotype, enhanceable by shg¹

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has visible phenotype, enhanceable by ft^G-rv

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has visible phenotype, enhanceable by ds⁵⁵

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by lilli⁰⁰⁶³²

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by Fas3^A183.1F2

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by l(2)dC9⁹

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by l(3)09291⁰⁹²⁹¹

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by stg²

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by tws⁰¹⁴³⁶

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has visible phenotype, enhanceable by lilli⁰⁰⁶³²

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has visible phenotype, enhanceable by Fas3^A183.1F2

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has visible phenotype, enhanceable by l(2)dC9⁹

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has visible phenotype, enhanceable by l(3)09291⁰⁹²⁹¹

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has visible phenotype, enhanceable by tws⁰¹⁴³⁶

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by Cdk1^B47

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, enhanceable by tyn^EP1421

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has visible phenotype, enhanceable by tyn^EP1421

(Greaves et al., 1999)

NOT Enhanced by

Statement

Reference

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, non-enhanceable by CadN^M19

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, non-enhanceable by kel^DE1

(Greaves et al., 1999)

Suppressed by

Statement

Reference

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, suppressible by sgg^M11/sgg[+]

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has visible phenotype, suppressible by dsh³

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has visible phenotype, suppressible by dsh^b117

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has visible phenotype, suppressible by wg^l-17

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, suppressible by dsh³

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, suppressible by dsh^b117

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, suppressible by wg[+]/wg^l-17

(Greaves et al., 1999)

NOT suppressed by

Statement

Reference

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, non-suppressible by CadN^M19

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has visible phenotype, non-suppressible by kel^DE1

(Greaves et al., 1999)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^en.PU, arm^UAS.cWa has wing margin bristle | ectopic phenotype, enhanceable by Traf4[+]/Traf4³

(Mathew et al., 2011)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing margin bristle | ectopic phenotype, enhanceable by Scer\GAL4^en-e16E/stg^UAS.cLa

(Marygold and Vincent, 2003)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing margin bristle | ectopic phenotype, enhanceable by stg⁷

(Marygold and Vincent, 2003)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing margin bristle | ectopic phenotype, enhanceable by stg⁸

(Marygold and Vincent, 2003)

Scer\GAL4^bbg-C96, arm^UAS.cWa has wing margin bristle | ectopic phenotype, enhanceable by stg^AR2

(Marygold and Vincent, 2003)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing margin bristle | ectopic phenotype, enhanceable by stg^AR2

(Marygold and Vincent, 2003)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing margin bristle | ectopic phenotype, enhanceable by sgg³²

(Marygold and Vincent, 2003)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing margin bristle | ectopic phenotype, enhanceable by Df(3R)01215

(Marygold and Vincent, 2003)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing margin bristle | ectopic phenotype, enhanceable by Df(3R)3450

(Marygold and Vincent, 2003)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing margin bristle | ectopic phenotype, enhanceable by stg²

(Marygold and Vincent, 2003)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing margin bristle | ectopic phenotype, enhanceable by stg⁴

(Marygold and Vincent, 2003)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing margin bristle | ectopic phenotype, enhanceable by stg⁵

(Marygold and Vincent, 2003)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by Scer\GAL4^en-e16E/tyn^EP1421

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has eye phenotype, enhanceable by Scer\GAL4^GMR.PF/tyn^EP1421

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing sensillum | ectopic phenotype, enhanceable by sgg^M11/sgg[+]

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has eye phenotype, enhanceable by sgg^M11

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by nkd²

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by shg¹

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by ft^G-rv

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by ds⁵⁵

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by crb^8F105

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by sdt^EH681

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by dlg1¹⁴

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by Egfr^f3

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by rho¹⁰

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by aos⁰⁰⁶

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by CycA³

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by Df(3L)pbl-X1

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has eye phenotype, enhanceable by shg¹

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has eye phenotype, enhanceable by ft^G-rv

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has eye phenotype, enhanceable by ds⁵⁵

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by lilli⁰⁰⁶³²

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by Fas3^A183.1F2

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by l(2)dC9⁹

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by l(3)09291⁰⁹²⁹¹

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by tws⁰¹⁴³⁶

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has eye phenotype, enhanceable by lilli⁰⁰⁶³²

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has eye phenotype, enhanceable by Fas3^A183.1F2

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has eye phenotype, enhanceable by l(2)dC9⁹

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by stg²

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has eye phenotype, enhanceable by l(3)09291⁰⁹²⁹¹

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has eye phenotype, enhanceable by tws⁰¹⁴³⁶

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, enhanceable by Cdk1^B47

(Greaves et al., 1999)

NOT Enhanced by

Statement

Reference

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, non-enhanceable by CadN^M19

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, non-enhanceable by kel^DE1

(Greaves et al., 1999)

Suppressed by

Statement

Reference

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, suppressible by dsh³

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has eye phenotype, suppressible by dsh³

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has eye phenotype, suppressible by dsh^b117

(Greaves et al., 1999)

Scer\GAL4^GMR.PF, arm^UAS.cWa has eye phenotype, suppressible by wg^l-17

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, suppressible by dsh^b117

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing | posterior phenotype, suppressible by wg[+]/wg^l-17

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing vein | ectopic phenotype, suppressible by sgg^M11/sgg[+]

(Greaves et al., 1999)

NOT suppressed by

Statement

Reference

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, non-suppressible by CadN^M19

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa has wing phenotype, non-suppressible by kel^DE1

(Greaves et al., 1999)

Other

Statement

Reference

Scer\GAL4^en-e16E, arm^UAS.cWa, wg[+]/wg^l-17 has wing margin bristle phenotype

(Greaves et al., 1999)

Scer\GAL4^en-e16E, arm^UAS.cWa, wg^l-17 has wing margin bristle phenotype

(Greaves et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

The wing margin bristle defects characteristic for meru¹ mutant flies cannot be exacerbated further by Scer\GAL4^nub.PU-driven expression arm^Scer\UAS.cWa.

(Banerjee et al., 2017)

The ectopic wing margin bristle phenotype caused by expression of arm^Scer\UAS.cWa under the control of Scer\GAL4^en.PU is enhanced by Traf4³/+.

(Mathew et al., 2011)

The eye phenotype caused by expression of arm^Scer\UAS.cWa under the control of Scer\GAL4^GMR.PF is suppressed by dsh^b117 and wg^l-17 and enhanced by sgg^M11. The phenotype caused by expression of arm^Scer\UAS.cWa under the control of Scer\GAL4^en-e16E is dominantly suppressed by wg^l-17. Also, wing margin bristles are lost between veins 4 and 5 in these flies. The extra bristle phenotype caused by expression of arm^Scer\UAS.cWa under the control of Scer\GAL4^en-e16E is enhanced by one copy of sgg^M11, while the vein abnormalities are suppressed in these flies.

(Greaves et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^arm.PS/arm^UAS.cWa rescues arm²

(White et al., 1998)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

arm^Scer\UAS.cWa

arm^UAS.cWa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of White

(White et al., 1998)

Secondary FlyBase IDs

References (7)

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