FlyBase Allele Report: Dmel\brm[K804R.UAS.Tag:HA]

General Information

Symbol

Dmel\brm^{K804R.UAS.Tag:HA}

Species

D. melanogaster

Name

FlyBase ID

FBal0086705

Feature type

allele

Associated gene

Dmel\brm

Associated Insertion(s)

Carried in Construct

P{UAS-brm.K804R.T:HA1}

Also Known As

UAS-brm[K804R], UAS-brm^K804R, UAS-brm^DN, brm^K804R, UASBrm^K804R, UAS-brm-DN

Key Links

Transgenic product class

missense_variant

(Elfring et al., 1998)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

missense_variant

(Elfring et al., 1998)

Mutagen

in vitro construct

(Elfring et al., 1998)

Progenitor genotype

Carried in construct

P{UAS-brm.K804R.T:HA1}

Cytology

Description

A 6.7kb fragment containing the brm coding sequence (with the amino acid replacement: K804R and tagged with Tag:HA), flanked by 66bp of 5' genomic DNA and approximately 1.3kb of 3' genomic DNA is expressed under the control of UAS regulatory sequences.

(Elfring et al., 1998)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

brm

Tagged with

Tag:HA

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates cancer

modeled by dlg1^HMS01954

(Bunker et al., 2015)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | P-stage, with Scer\GAL4^ppk.PU

(Zhang et al., 2014)

abnormal size | adult stage, with Scer\GAL4^ey.PH

(Dietz et al., 2015)

abnormal size | adult stage, with Scer\GAL4^ey.PU

(Morimoto et al., 2016)

increased cell number | larval stage, with Scer\GAL4^wor.PA, Scer\GAL80^ase.PN

(Rives-Quinto et al., 2020)

lethal, with Scer\GAL4^{neur-GAL4-A101}

(Armstrong et al., 2005)

lethal | heat sensitive, with Scer\GAL4^69B

(Elfring et al., 1998)

lethal | pupal stage, with Scer\GAL4^{neur-GAL4-A101}

(Armstrong et al., 2005)

lethal - all die before end of P-stage | partially, with Scer\GAL4^ey.PH

(Papoulas et al., 2001)

some die during pharate adult stage | partially, with Scer\GAL4^ey.PH

(Papoulas et al., 2001)

visible, with Df(3L)brm11, Scer\GAL4^ey.PH

(Armstrong et al., 2005)

visible, with Scer\GAL4^69B

(Marenda et al., 2004, Elfring et al., 1998)

visible, with Scer\GAL4^bi-omb-Gal4

(Collins et al., 1999)

visible, with Scer\GAL4^en-e16E

(Herr et al., 2010)

visible, with Scer\GAL4^ey.PH

(Armstrong et al., 2005, Mollaaghababa et al., 2001)

visible, with Scer\GAL4^ey.PH, brm²

(Armstrong et al., 2005)

visible, with Scer\GAL4^ey.PH, brm⁷⁹⁵

(Armstrong et al., 2005)

visible, with Scer\GAL4^ey.PH, brm⁹⁶³

(Armstrong et al., 2005)

visible, with Scer\GAL4^ey.PH, brm¹⁶³⁰

(Armstrong et al., 2005)

visible, with Scer\GAL4^ey.PH, brm²⁴¹⁹

(Armstrong et al., 2005)

visible, with Scer\GAL4^ey.PH, brm³²⁴⁴

(Armstrong et al., 2005)

visible, with Scer\GAL4^ey.PH, brm³³⁶⁹

(Armstrong et al., 2005)

visible, with Scer\GAL4^vg.PM

(Collins et al., 1999)

visible | adult stage, with Scer\GAL4^ey.PH

(Dietz et al., 2015)

visible | adult stage, with Scer\GAL4^ey.PU

(Morimoto et al., 2016)

Phenotype Manifest In

campaniform sensillum | ectopic, with Scer\GAL4^69B

(Elfring et al., 1998)

dendritic tree | P-stage, with Scer\GAL4^ppk.PU

(Zhang et al., 2014)

embryonic/larval brain | larval stage, with Scer\GAL4^wor.PA, Scer\GAL80^ase.PN

(Rives-Quinto et al., 2020)

eo neuron | ectopic, with Scer\GAL4^{neur-GAL4-A101}

(Armstrong et al., 2005)

eye, with Df(3L)brm11, Scer\GAL4^ey.PH

(Armstrong et al., 2005)

eye, with Scer\GAL4^ey.PH

(Dietz et al., 2015, Armstrong et al., 2005, Moshkin et al., 2002, Mollaaghababa et al., 2001, Papoulas et al., 2001)

eye, with Scer\GAL4^ey.PH, brm²

(Armstrong et al., 2005)

eye, with Scer\GAL4^ey.PH, brm⁷⁹⁵

(Armstrong et al., 2005)

eye, with Scer\GAL4^ey.PH, brm⁹⁶³

(Armstrong et al., 2005)

eye, with Scer\GAL4^ey.PH, brm¹⁶³⁰

(Armstrong et al., 2005)

eye, with Scer\GAL4^ey.PH, brm²⁴¹⁹

(Armstrong et al., 2005)

eye, with Scer\GAL4^ey.PH, brm³²⁴⁴

(Armstrong et al., 2005)

eye, with Scer\GAL4^ey.PH, brm³³⁶⁹

(Armstrong et al., 2005)

eye, with Scer\GAL4^ey.PU

(Morimoto et al., 2016)

larval dorsal multidendritic neuron ddaC | P-stage, with Scer\GAL4^ppk.PU

(Zhang et al., 2014)

macrochaeta & wing, with Scer\GAL4^69B

(Elfring et al., 1998)

macrochaeta | ectopic, with Scer\GAL4^69B

(Elfring et al., 1998)

mechanosensory chaeta, with Scer\GAL4^69B

(Elfring et al., 1998)

ommatidium, with Scer\GAL4^ey.PH

(Armstrong et al., 2005)

ommatidium, with Scer\GAL4^ey.PH, brm²

(Armstrong et al., 2005)

ommatidium, with Scer\GAL4^ey.PH, brm³³⁶⁹

(Armstrong et al., 2005)

posterior crossvein, with Scer\GAL4^69B

(Marenda et al., 2004, Elfring et al., 1998)

posterior crossvein, with Scer\GAL4^en-e16E

(Herr et al., 2010)

prothoracic leg, with Scer\GAL4^69B

(Elfring et al., 1998)

sensillum campaniformium & wing, with Scer\GAL4^69B

(Elfring et al., 1998)

sex comb, with Scer\GAL4^69B

(Elfring et al., 1998)

thecogen cell, with Scer\GAL4^{neur-GAL4-A101}

(Armstrong et al., 2005)

tormogen cell, with Scer\GAL4^{neur-GAL4-A101}

(Armstrong et al., 2005)

type II neuroblast | increased number | larval stage, with Scer\GAL4^wor.PA, Scer\GAL80^ase.PN

(Rives-Quinto et al., 2020)

wing, with Scer\GAL4^69B

(Elfring et al., 1998)

wing, with Scer\GAL4^bi-omb-Gal4

(Collins et al., 1999)

wing, with Scer\GAL4^vg.PM

(Collins et al., 1999)

wing disc | third instar larval stage, with Scer\GAL4^hs.PB

(Herr et al., 2010)

wing margin bristle | ectopic, with Scer\GAL4^bi-omb-Gal4

(Collins et al., 1999)

wing margin bristle | posterior | proximal, with Scer\GAL4^vg.PM

(Collins et al., 1999)

wing sensillum | ectopic, with Scer\GAL4^bi-omb-Gal4

(Collins et al., 1999)

wing vein, with Scer\GAL4^69B

(Marenda et al., 2004)

wing vein, with Scer\GAL4^bi-omb-Gal4

(Collins et al., 1999)

wing vein L5, with Scer\GAL4^69B

(Elfring et al., 1998)

wing vein L5, with Scer\GAL4^en-e16E

(Herr et al., 2010)

wing vein L5 | distal, with Scer\GAL4^69B

(Marenda et al., 2004)

Detailed Description

Statement

Reference

Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^C587 does not cause any obvious defects in germaria morphology and development.

(Li et al., 2016)

Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^ey.PU results in small and rough eye phenotype in adult flies.

(Morimoto et al., 2016)

Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^ey.PH results in small eye phenotype in adults.

(Dietz et al., 2015)

Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^wor.PA has no effect on neuroblast number.

(Janssens et al., 2014)

Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} via the Scer\GAL4^en-e16E driver leads to a loss of the L5 wing vein and loss of the posterior cross vein.

Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} driven by Scer\GAL4^hs.PB results in a slight increase of S-phase cells in third instar imaginal wing discs compared with controls. Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} has little effect on mitosis or cell survival.

(Herr et al., 2010)

Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^da.G32 does not alter the morphology of mitotic chromosomes prepared from neuroblasts of third instar larvae.

(Corona et al., 2007)

Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^ey.PH results in flies with eyes that are slightly rough and reduced in size. The severity of the phenotype is enhanced if the flies also carry brm², brm³³⁶⁹ or Df(3L)brm11. Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^{neur-GAL4-A101} results in high embryonic or larval lethality (78%), early pupal lethality (17%) and midpupal lethality (5%). Pupae expressing brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^{neur-GAL4-A101} contain variable-sized patches of tissue containing wild-type or defective sensory organ precursor (SOP) lineages. The defective SOP lineages contain fewer socket cells, fewer sheath cells and extra neurons.

(Armstrong et al., 2005)

Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^69B at 18^oC results in the loss of distal portions of wing vein L5 and deletion of the posterior crossvein.

(Marenda et al., 2004)

brm^{K804R.Scer\UAS.T:Ivir\HA1}; Scer\GAL4^ey.PH flies have a rough eye phenotype.

(Moshkin et al., 2002)

Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^ey.PH results in a rough eye phenotype.

(Mollaaghababa et al., 2001)

brm^{K804R.Scer\UAS.T:Ivir\HA1} when driven by Scer\GAL4^ey.PH produces flies with slightly smaller or rough eyes. A small percentage of these flies die as pharate adults.

(Papoulas et al., 2001)

When expression is driven by Scer\GAL4^bi-omb-Gal4, loss of the distal wing margin, formation of ectopic campaniform sensillae and wing margin bristles and disruptions of wing vein morphology are seen. Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} at the wing margin driven by Scer\GAL4^vg.PM, results in a loss the proximal, posterior wing margin.

(Collins et al., 1999)

Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^h-1J3 or Scer\GAL4^en-e16E has no effect on embryonic viability or segmentation. Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} in imaginal tissues under the control of Scer\GAL4^69B causes greater than 99% lethality. At 25^oC or higher, the majority of these animals pupate but fail to differentiate. Some flies expressing brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^69B can survive to adulthood when raised at 20^oC. These animals show partial transformation of first leg to second leg, as shown by a reduction in the number of sex comb teeth. These flies also show twinning of mechanosensory bristles. Wings are reduced in size, and the posterior crossvein and vein L5 are usually missing. Defects in the wing campaniform sensilla are also seen, including missing sensilla, duplication or triplication of sensilla, transformation of sensilla into bristles and the appearance of ectopic sensilla. Ectopic sensilla and bristles are most often seen on the L3 vein.

(Elfring et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^ey.PU, brm^{K804R.UAS.Tag:HA} has visible | adult stage phenotype, enhanceable by Marcal1^del/Marcal1^del

(Morimoto et al., 2016)

Scer\GAL4^ey.PU, brm^{K804R.UAS.Tag:HA} has abnormal size | adult stage phenotype, enhanceable by Marcal1^del/Marcal1^del

(Morimoto et al., 2016)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible | adult stage phenotype, enhanceable by htt^GD14943/Scer\GAL4^ey.PH

(Dietz et al., 2015)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has abnormal size | adult stage phenotype, enhanceable by htt^GD14943/Scer\GAL4^ey.PH

(Dietz et al., 2015)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by Snr1^R3/Snr1[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by Df(3L)XDI98/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by Df(3L)ZN47/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by Df(3L)emc-E12/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by Df(3L)fz-GF3b/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by Df(3L)st-f13/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by Df(3L)vin2/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by Df(3L)vin5/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by Df(3R)3450/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by +/Df(3R)Delta-BX12

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by Df(3R)Scr/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by Df(3R)T-32/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by Df(3R)by10/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by Df(3R)crb-F89-4/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by Delta²³⁷¹/Dl[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by Delta^9P/Dl[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by N^264-39

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by RpII140[+]/Polr2B^A5

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by Polr2B^Z45

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by RpII140[+]/Polr2B^brie

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by Polr2A⁴

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by mor[+]/mor³⁰⁹⁰

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by vn[+]/vn¹⁰⁵⁶⁷

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by vn[+]/vn⁶⁴³

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by zen²/zen[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by zen⁴³⁶/zen[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by zen⁷¹⁴/zen[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has some die during P-stage phenotype, enhanceable by Df(1)18.1.15

(Papoulas et al., 2001)

Scer\GAL4^bi-omb-Gal4, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by osa³⁰⁸

(Collins et al., 1999)

Scer\GAL4^vg.PM, brm^{K804R.UAS.Tag:HA} has visible phenotype, enhanceable by osa³⁰⁸

(Collins et al., 1999)

NOT Enhanced by

Statement

Reference

Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, brm^{K804R.UAS.Tag:HA} has increased cell number | larval stage phenotype, non-enhanceable by ham²/ham[+]

(Rives-Quinto et al., 2020)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by MED24^BG01670

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by Taf10b^KG01574

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by Taf4¹

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by btl^dev2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by grk³

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by kis¹

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by skd¹

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by skd²

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by skd^rK760

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by spi¹

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by spi^s3547

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by trx^E2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by vtd²

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by Nsf2^urd-2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by Df(3L)81k19

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by Df(3L)kto2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by Df(3L)lxd6

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by Df(3L)lxd6/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by Df(3R)DG2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by Df(3R)mbc-R1/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by MED17^s9256

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by MED23^KG00948

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by Hsc70-4⁰³⁵⁵⁰

(Mollaaghababa et al., 2001)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by Hsc70-4^II-R35-R7

(Mollaaghababa et al., 2001)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-enhanceable by Hsc70-4^54.1

(Mollaaghababa et al., 2001)

Suppressed by

Statement

Reference

Scer\GAL4^ppk.PU, brm^{K804R.UAS.Tag:HA} has abnormal neuroanatomy | P-stage phenotype, suppressible | partially by Nrg^HMS01638, Scer\GAL4^ppk.PU

(Zhang et al., 2014)

Scer\GAL4^69B, brm^{K804R.UAS.Tag:HA} has visible phenotype, suppressible by Snr1^E1/Snr1[+]

(Marenda et al., 2004)

Df(1)18.1.15, Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has some die during P-stage phenotype, suppressible by Bap111^{UAS.Tag:HA,Tag:polyHis}, Scer\GAL4^ey.PH

(Papoulas et al., 2001)

Df(1)18.1.15, Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has some die during P-stage phenotype, suppressible | partially by Bap111^{UAS.ΔHMG.Tag:HA,Tag:polyHis}, Scer\GAL4^ey.PH

(Papoulas et al., 2001)

NOT suppressed by

Statement

Reference

Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, brm^{K804R.UAS.Tag:HA} has increased cell number | larval stage phenotype, non-suppressible by ham²/ham[+]

(Rives-Quinto et al., 2020)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by MED17^s9256

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by MED23^KG00948

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by MED24^BG01670

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by Taf10b^KG01574

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by Taf4¹

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by btl^dev2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by grk³

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by kis¹

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by skd¹

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by skd²

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by skd^rK760

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by spi¹

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by spi^s3547

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by trx^E2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by Nsf2^urd-2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by vtd²

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by Df(3L)81k19

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by Df(3L)kto2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by Df(3L)lxd6

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by Df(3R)DG2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by Hsc70-4⁰³⁵⁵⁰

(Mollaaghababa et al., 2001)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by Hsc70-4^54.1

(Mollaaghababa et al., 2001)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has visible phenotype, non-suppressible by Hsc70-4^II-R35-R7

(Mollaaghababa et al., 2001)

Enhancer of

Statement

Reference

Scer\GAL4^GMR9D11/brm^{K804R.UAS.Tag:HA} is an enhancer of abnormal neuroanatomy phenotype of brat^DG19310/brat¹¹

(Janssens et al., 2014)

Scer\GAL4^wor.PA/brm^{K804R.UAS.Tag:HA} is an enhancer of abnormal neuroanatomy phenotype of brat^DG19310/brat¹¹

(Janssens et al., 2014)

Scer\GAL4^wor.PA/brm^{K804R.UAS.Tag:HA} is an enhancer of abnormal neuroanatomy phenotype of Df(2L)erm²/erm¹, erm^Tag:FLAG

(Janssens et al., 2014)

Scer\GAL4^bbg-C96/brm^{K804R.UAS.Tag:HA} is an enhancer of visible phenotype of ct^53d

(Krupp et al., 2005)

NOT Enhancer of

Statement

Reference

Scer\GAL4^wor.PA, brm^{K804R.UAS.Tag:HA}, Scer\GAL80^ase.PN is a non-enhancer of increased cell number | larval stage | dominant phenotype of ham²

(Rives-Quinto et al., 2020)

Scer\GAL4^GMR9D11/brm^{K804R.UAS.Tag:HA} is a non-enhancer of abnormal neuroanatomy phenotype of brat^DG19310/brat¹¹

(Janssens et al., 2014)

brm^{K804R.UAS.Tag:HA}/Scer\GAL4^hs.PB is a non-enhancer of abnormal mitotic cell cycle | third instar larval stage phenotype of Scer\GAL4^hs.PB, geminin^UAS.cQa

(Herr et al., 2010)

brm^{K804R.UAS.Tag:HA}, Scer\GAL4^bbg-C96 is a non-enhancer of visible phenotype of Raf^UAS.F179, Scer\GAL4^bbg-C96

(Herr et al., 2010)

Suppressor of

Statement

Reference

Scer\GAL4^C587/brm^{K804R.UAS.Tag:HA} is a suppressor | partially of increased cell number | female | adult stage phenotype of Scer\GAL4^C587, ph-p^GD17398

(Li et al., 2016)

Scer\GAL4^C587/brm^{K804R.UAS.Tag:HA} is a suppressor | partially of neoplasia | female | adult stage phenotype of Scer\GAL4^C587, ph-p^GD17398

(Li et al., 2016)

brm^{K804R.UAS.Tag:HA}/Scer\GAL4^Bx-MS1096 is a suppressor | partially of neoplasia | third instar larval stage phenotype of Scer\GAL4^Bx-MS1096, dlg1^HMS01954

(Bunker et al., 2015)

geminin^UAS.cQa/brm^{K804R.UAS.Tag:HA}, Scer\GAL4^bbg-C96 is a suppressor | partially of visible phenotype of Raf^UAS.F179, Scer\GAL4^bbg-C96

(Herr et al., 2010)

Scer\GAL4^bbg-C96/brm^{K804R.UAS.Tag:HA} is a suppressor of visible phenotype of ct^K

(Krupp et al., 2005)

NOT Suppressor of

Statement

Reference

Scer\GAL4^wor.PA, brm^{K804R.UAS.Tag:HA}, Scer\GAL80^ase.PN is a non-suppressor of increased cell number | dominant | larval stage phenotype of ham²

(Rives-Quinto et al., 2020)

brm^{K804R.UAS.Tag:HA}, Scer\GAL4^bbg-C96 is a non-suppressor of visible phenotype of Raf^UAS.F179, Scer\GAL4^bbg-C96

(Herr et al., 2010)

Other

Statement

Reference

Scer\GAL4^Bx-MS1096, brm^{K804R.UAS.Tag:HA}, scrib^HMS01490 has lethal phenotype

(Bunker et al., 2015)

Scer\GAL4^en-e16E, brm^{K804R.UAS.Tag:HA}, geminin^UAS.cQa has lethal | first instar larval stage phenotype

(Herr et al., 2010)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^ey.PU, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Marcal1^del/Marcal1^del

(Morimoto et al., 2016)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by htt^GD14943/Scer\GAL4^ey.PH

(Dietz et al., 2015)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Snr1^R3/Snr1[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has ommatidium phenotype, enhanceable by Snr1^R3/Snr1[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Df(3L)XDI98/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Df(3L)ZN47/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Df(3L)emc-E12/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Df(3L)fz-GF3b/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Df(3L)st-f13/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Df(3L)vin2/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Df(3L)vin5/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Df(3R)3450/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by +/Df(3R)Delta-BX12

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Df(3R)Scr/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Df(3R)T-32/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Df(3R)by10/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Df(3R)crb-F89-4/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Delta²³⁷¹/Dl[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has ommatidium phenotype, enhanceable by Delta²³⁷¹/Dl[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Delta^9P/Dl[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has ommatidium phenotype, enhanceable by Delta^9P/Dl[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by N^264-39

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by RpII140[+]/Polr2B^A5

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has ommatidium phenotype, enhanceable by RpII140[+]/Polr2B^A5

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Polr2B^Z45

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by RpII140[+]/Polr2B^brie

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has ommatidium phenotype, enhanceable by RpII140[+]/Polr2B^brie

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Polr2A⁴

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by mor[+]/mor³⁰⁹⁰

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has ommatidium phenotype, enhanceable by mor[+]/mor³⁰⁹⁰

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by vn[+]/vn¹⁰⁵⁶⁷

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has ommatidium phenotype, enhanceable by vn[+]/vn¹⁰⁵⁶⁷

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by vn[+]/vn⁶⁴³

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has ommatidium phenotype, enhanceable by vn[+]/vn⁶⁴³

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by zen²/zen[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has ommatidium phenotype, enhanceable by zen²/zen[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by zen⁴³⁶/zen[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has ommatidium phenotype, enhanceable by zen⁴³⁶/zen[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by zen⁷¹⁴/zen[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has ommatidium phenotype, enhanceable by zen⁷¹⁴/zen[+]

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by asf1^UAS.cMa

(Moshkin et al., 2002)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, enhanceable by Df(1)18.1.15

(Papoulas et al., 2001)

Scer\GAL4^bi-omb-Gal4, brm^{K804R.UAS.Tag:HA} has wing phenotype, enhanceable by osa³⁰⁸

(Collins et al., 1999)

Scer\GAL4^bi-omb-Gal4, brm^{K804R.UAS.Tag:HA} has wing sensillum | ectopic phenotype, enhanceable by osa³⁰⁸

(Collins et al., 1999)

Scer\GAL4^bi-omb-Gal4, brm^{K804R.UAS.Tag:HA} has wing margin bristle | ectopic phenotype, enhanceable by osa³⁰⁸

(Collins et al., 1999)

Scer\GAL4^bi-omb-Gal4, brm^{K804R.UAS.Tag:HA} has wing vein phenotype, enhanceable by osa³⁰⁸

(Collins et al., 1999)

Scer\GAL4^vg.PM, brm^{K804R.UAS.Tag:HA} has wing phenotype, enhanceable by osa³⁰⁸

(Collins et al., 1999)

Scer\GAL4^vg.PM, brm^{K804R.UAS.Tag:HA} has wing margin bristle phenotype, enhanceable by osa³⁰⁸

(Collins et al., 1999)

NOT Enhanced by

Statement

Reference

Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, brm^{K804R.UAS.Tag:HA} has type II neuroblast | larval stage | increased number phenotype, non-enhanceable by ham²/ham[+]

(Rives-Quinto et al., 2020)

Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, brm^{K804R.UAS.Tag:HA} has embryonic/larval brain | larval stage phenotype, non-enhanceable by ham²/ham[+]

(Rives-Quinto et al., 2020)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by MED24^BG01670

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by Taf10b^KG01574

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by Taf4¹

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by btl^dev2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by grk³

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by kis¹

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by skd¹

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by skd²

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by skd^rK760

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by spi¹

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by spi^s3547

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by trx^E2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by vtd²

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by Nsf2^urd-2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by Df(3L)81k19

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by Df(3L)kto2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by Df(3L)lxd6

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by Df(3L)lxd6/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by Df(3R)DG2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by Df(3R)mbc-R1/+

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by MED17^s9256

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by MED23^KG00948

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by Hsc70-4⁰³⁵⁵⁰

(Mollaaghababa et al., 2001)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by Hsc70-4^II-R35-R7

(Mollaaghababa et al., 2001)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-enhanceable by Hsc70-4^54.1

(Mollaaghababa et al., 2001)

Suppressed by

Statement

Reference

Scer\GAL4^ppk.PU, brm^{K804R.UAS.Tag:HA} has larval dorsal multidendritic neuron ddaC | P-stage phenotype, suppressible | partially by Nrg^HMS01638, Scer\GAL4^ppk.PU

(Zhang et al., 2014)

Scer\GAL4^ppk.PU, brm^{K804R.UAS.Tag:HA} has dendritic tree | P-stage phenotype, suppressible | partially by Nrg^HMS01638, Scer\GAL4^ppk.PU

(Zhang et al., 2014)

Scer\GAL4^69B, brm^{K804R.UAS.Tag:HA} has posterior crossvein phenotype, suppressible by Snr1^E1/Snr1[+]

(Marenda et al., 2004)

Scer\GAL4^69B, brm^{K804R.UAS.Tag:HA} has wing vein L5 | distal phenotype, suppressible by Snr1^E1/Snr1[+]

(Marenda et al., 2004)

Scer\GAL4^69B, brm^{K804R.UAS.Tag:HA} has wing vein phenotype, suppressible by Snr1^R3/Snr1[+]

(Marenda et al., 2004)

Df(1)18.1.15, Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, suppressible | partially by Bap111^{UAS.ΔHMG.Tag:HA,Tag:polyHis}

(Papoulas et al., 2001)

Df(1)18.1.15, Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, suppressible by Bap111^{UAS.Tag:HA,Tag:polyHis}

(Papoulas et al., 2001)

NOT suppressed by

Statement

Reference

Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, brm^{K804R.UAS.Tag:HA} has type II neuroblast | increased number | larval stage phenotype, non-suppressible by ham²/ham[+]

(Rives-Quinto et al., 2020)

Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, brm^{K804R.UAS.Tag:HA} has embryonic/larval brain | larval stage phenotype, non-suppressible by ham²/ham[+]

(Rives-Quinto et al., 2020)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by Df(3L)81k19

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by Df(3L)kto2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by Df(3L)lxd6

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by Df(3R)DG2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by MED17^s9256

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by MED23^KG00948

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by MED24^BG01670

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by Taf10b^KG01574

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by Taf4¹

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by btl^dev2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by grk³

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by kis¹

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by skd¹

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by skd²

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by skd^rK760

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by spi¹

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by spi^s3547

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by trx^E2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by Nsf2^urd-2

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by vtd²

(Armstrong et al., 2005)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by Hsc70-4⁰³⁵⁵⁰

(Mollaaghababa et al., 2001)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by Hsc70-4^54.1

(Mollaaghababa et al., 2001)

Scer\GAL4^ey.PH, brm^{K804R.UAS.Tag:HA} has eye phenotype, non-suppressible by Hsc70-4^II-R35-R7

(Mollaaghababa et al., 2001)

Enhancer of

Statement

Reference

Scer\GAL4^GMR9D11/brm^{K804R.UAS.Tag:HA} is an enhancer of type II neuroblast | increased number phenotype of brat^DG19310/brat¹¹

(Janssens et al., 2014)

Scer\GAL4^wor.PA/brm^{K804R.UAS.Tag:HA} is an enhancer of type II neuroblast | increased number phenotype of brat^DG19310/brat¹¹

(Janssens et al., 2014)

Scer\GAL4^wor.PA/brm^{K804R.UAS.Tag:HA} is an enhancer of type II neuroblast | increased number phenotype of Df(2L)erm²/erm¹, erm^Tag:FLAG

(Janssens et al., 2014)

Scer\GAL4^bbg-C96/brm^{K804R.UAS.Tag:HA} is an enhancer of wing phenotype of ct^53d

(Krupp et al., 2005)

brm^{K804R.UAS.Tag:HA}/Scer\GAL4^ey.PH is an enhancer of eye phenotype of Scer\GAL4^ey.PH, osa^UAS.cCa

(Collins et al., 1999)

NOT Enhancer of

Statement

Reference

Scer\GAL4^wor.PA, brm^{K804R.UAS.Tag:HA}, Scer\GAL80^ase.PN is a non-enhancer of type II neuroblast | larval stage | increased number phenotype of ham²

(Rives-Quinto et al., 2020)

Scer\GAL4^wor.PA, brm^{K804R.UAS.Tag:HA}, Scer\GAL80^ase.PN is a non-enhancer of embryonic/larval brain | larval stage phenotype of ham²

(Rives-Quinto et al., 2020)

Scer\GAL4^GMR9D11/brm^{K804R.UAS.Tag:HA} is a non-enhancer of type II neuroblast | increased number phenotype of brat^DG19310/brat¹¹

(Janssens et al., 2014)

brm^{K804R.UAS.Tag:HA}, Scer\GAL4^bbg-C96 is a non-enhancer of wing margin phenotype of Raf^UAS.F179, Scer\GAL4^bbg-C96

(Herr et al., 2010)

Scer\GAL4^bbg-C96/brm^{K804R.UAS.Tag:HA} is a non-enhancer of phenotype of ct^2s

(Krupp et al., 2005)

Scer\GAL4^bbg-C96/brm^{K804R.UAS.Tag:HA} is a non-enhancer of phenotype of ct⁶

(Krupp et al., 2005)

Suppressor of

Statement

Reference

Scer\GAL4^C587/brm^{K804R.UAS.Tag:HA} is a suppressor | partially of germarium phenotype of Scer\GAL4^C587, ph-p^GD17398

(Li et al., 2016)

brm^{K804R.UAS.Tag:HA}/Scer\GAL4^Bx-MS1096 is a suppressor | partially of wing disc | third instar larval stage phenotype of Scer\GAL4^Bx-MS1096, dlg1^HMS01954

(Bunker et al., 2015)

geminin^UAS.cQa/brm^{K804R.UAS.Tag:HA}, Scer\GAL4^bbg-C96 is a suppressor | partially of wing margin phenotype of Raf^UAS.F179, Scer\GAL4^bbg-C96

(Herr et al., 2010)

Scer\GAL4^bbg-C96/brm^{K804R.UAS.Tag:HA} is a suppressor of triple row of wing sensilla phenotype of ct^K

(Krupp et al., 2005)

brm^{K804R.UAS.Tag:HA}/Scer\GAL4^vg.PM is a suppressor of wing phenotype of Scer\GAL4^vg.PM, osa^UAS.cCa

(Collins et al., 1999)

NOT Suppressor of

Statement

Reference

Scer\GAL4^wor.PA, brm^{K804R.UAS.Tag:HA}, Scer\GAL80^ase.PN is a non-suppressor of type II neuroblast | increased number | larval stage phenotype of ham²

(Rives-Quinto et al., 2020)

Scer\GAL4^wor.PA, brm^{K804R.UAS.Tag:HA}, Scer\GAL80^ase.PN is a non-suppressor of embryonic/larval brain | larval stage phenotype of ham²

(Rives-Quinto et al., 2020)

brm^{K804R.UAS.Tag:HA}, Scer\GAL4^bbg-C96 is a non-suppressor of wing margin phenotype of Raf^UAS.F179, Scer\GAL4^bbg-C96

(Herr et al., 2010)

Scer\GAL4^bbg-C96/brm^{K804R.UAS.Tag:HA} is a non-suppressor of phenotype of ct^2s

(Krupp et al., 2005)

Scer\GAL4^bbg-C96/brm^{K804R.UAS.Tag:HA} is a non-suppressor of phenotype of ct⁶

(Krupp et al., 2005)

Additional Comments

Genetic Interactions

Statement

Reference

The tumorigenic accumulation of germline stem cell-like cells in germaria, characteristic for females expressing ph-p^GD17398 under the control of Scer\GAL4^C587 (together with tub-Gal80[ts] to limit the time of expression to adulthood) is strongly suppressed by co-expression of brm^{K804R.Scer\UAS.T:Ivir\HA1}.

(Li et al., 2016)

The small and rough eye phenotype observed in adult flies expressing brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^ey.PU is exacerbated further by Marcal1^del homozygosity.

(Morimoto et al., 2016)

The co-expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} and scrib^HMS01490 under the control of Scer\GAL4^Bx-MS1096 is synthetic lethal.

The co-expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} suppresses the tumor phenotype and tissue disorganization resulting from the expression of dlg1^HMS01954 under the control of Scer\GAL4^Bx-MS1096.

(Bunker et al., 2015)

The small adult eye phenotype induced by expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^ey.PH is further worsened by co-expression of htt^GD14943.

(Dietz et al., 2015)

Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of an insertion of Scer\GAL4^GMR9D11 that expresses in ase[-] immature Intermediate Neural Progenitors (INPs) (P{GMR9D11-GAL4}2) enhances the supernumerary neuroblast phenotype seen in brat^DG19310/brat¹¹ mutant larval brains. Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^wor.PA also enhances the phenotype. No enhancement is seen when brm^{K804R.Scer\UAS.T:Ivir\HA1} is expressed using an insertion of Scer\GAL4^GMR9D11 that expresses in ase[+] INPs (P{GMR9D11-GAL4}attP2).

Expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^wor.PA enhances the supernumerary neuroblast phenotype seen in hypomorphic erm mutant larval brains (erm¹/Df(2L)erm² mutants expressing erm^T:Zzzz\FLAG).

(Janssens et al., 2014)

Co-expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} and geminin^Scer\UAS.cQa driven by Scer\GAL4^en-e16E causes a dramatic developmental defect leading to lethality during the first instar larval stage.

Co-expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} driven by Scer\GAL4^hs.PB does not enhance the S-phase, mitotic and cell death phenotypes of geminin^Scer\UAS.cQa expression.

Co-expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} with phl^{Scer\UAS.F179} via Scer\GAL4^bbg-C96 does not significantly affect the notched wing phenotype resulting from the expression of phl^{Scer\UAS.F179} alone.

Co-expression of both brm^{K804R.Scer\UAS.T:Ivir\HA1} and geminin^Scer\UAS.cQa with phl^{Scer\UAS.F179} via Scer\GAL4^bbg-C96 results in a significant suppression of the notched wing phenotype resulting from the expression of phl^{Scer\UAS.F179} alone.

(Herr et al., 2010)

The loss of wing vein L5 and the posterior crossvein seen in animals expressing brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^69B at 18^oC is suppressed by Snr1^E1/+. The loss of wing veins seen in animals expressing brm^{K804R.Scer\UAS.T:Ivir\HA1} under the control of Scer\GAL4^69B is suppressed by Snr1^R3.

(Marenda et al., 2004)

The rough eye phenotype of brm^{K804R.Scer\UAS.T:Ivir\HA1}; Scer\GAL4^ey.PH flies is enhanced by asf1^Scer\UAS.cMa.

(Moshkin et al., 2002)

The majority of brm^{K804R.Scer\UAS.T:Ivir\HA1}, Scer\GAL4^ey.PH, Df(1)18.1.15 flies fail, to eclose with extremely rough, reduced or missing eyes. This enhancement is suppressible by the addition of dalao^{Scer\UAS.T:Ivir\HA1,T:Zzzz\His6}.

(Papoulas et al., 2001)

The wing phenotypes caused by expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} driven by Scer\GAL4^bi-omb-Gal4 are strongly enhanced by the addition of osa³⁰⁸. The wing phenotypes caused by expression of brm^{K804R.Scer\UAS.T:Ivir\HA1} driven by Scer\GAL4^vg.PM are enhanced by osa³⁰⁸. This phenotype is suppressed by the addition of osa^Scer\UAS.cCa. The addition of brm^{K804R.Scer\UAS.T:Ivir\HA1} suppresses the wing hinge and small wing size phenotypes seen in osa^Scer\UAS.cCa/Scer\GAL4^vg.PM flies. The addition of brm^{K804R.Scer\UAS.T:Ivir\HA1} enhances the variable eye size phenotype seen in osa^Scer\UAS.cCa/Scer\GAL4^ey.PH flies.

(Collins et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

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Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

BRM^K804R

(Armstrong et al., 2002)

brm^{K804R.Scer\UAS.T:Ivir\HA1}

brm^{K804R.UAS.T:HA1}

brm^{K804R.UAS.Tag:HA}

brm^K804R

(Burgio et al., 2008, Marenda et al., 2004)

Name Synonyms

Secondary FlyBase IDs

References (26)

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