FlyBase Allele Report: Dmel\Smg5[34Eb-2]

General Information

Symbol

Dmel\Smg5^34Eb-2

Species

D. melanogaster

Name

FlyBase ID

FBal0008433

Feature type

allele

Associated gene

Dmel\Smg5

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Ashburner et al., 1999.10.12, Tatei et al., 1995)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with Df(2L)BSC345)

(Cook, 2022.7.7)

lethal (with Df(2L)BSC694)

(Cook, 2022.7.7)

lethal (with Smg5^C391)

(Cook, 2022.7.7)

lethal (with Smg5^G115)

(Cook, 2022.7.7)

lethal | recessive

(Tatei et al., 1995)

male sterile

(Hurst et al., 2003)

male sterile (with Df(2L)BSC694)

(Christensen et al., 2008.12.28)

male sterile (with Smg5^34Eb-1)

(Hurst et al., 2003)

partially lethal - majority live (with Smg5^34Eb-1)

(Hurst et al., 2003)

viable

(Hurst et al., 2003)

Phenotype Manifest In

testis

(Hurst et al., 2003)

testis (with Df(2L)Adh-nBR55)

(Hurst et al., 2003)

testis (with Df(2L)b88f32)

(Hurst et al., 2003)

testis (with Smg5^34Eb-1)

(Hurst et al., 2003)

Detailed Description

Statement

Reference

Incompatible crosses between Wolbachia-infected wild type males and uninfected Smg5^34Eb-2 females show a higher egg hatch rate (40%) relative to controls (26-30%).

(Xi et al., 2008)

The testes of Smg5^34Eb-2 homozygous males or Smg5^34Eb-2/Smg5^34Eb-1 males are extremely variable in appearance. Most are small with few elongated spermatids, no individualised sperm, and degeneration of variable extent.

(Hurst et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Smg5^C391

(Cook, 2022.7.7)

Smg5^G115

(Cook, 2022.7.7)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

O'Donnell.

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

Ance^34Eb-2

(Kim et al., 2017, Christensen et al., 2008.12.28, Christensen and Cook, 2007.3.22, Christensen and Cook, 2007.3.22)

DM12

Smg5^34Eb-2

ance ^34Eb-2

(Xi et al., 2008)

l(2)34Eb2

(Xi et al., 2008)

l(2)34Eb²

(Cook, 2022.7.7, Tatei et al., 1995)

l(2)br31^DM12

(Tatei et al., 1995)

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections

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