FlyBase Allele Report: Dmel\dpp[s5]

General Information

Symbol

Dmel\dpp^s5

Species

D. melanogaster

Name

FlyBase ID

FBal0003075

Feature type

allele

Associated gene

Dmel\dpp

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

(Segal and Gelbart, 1985)

Progenitor genotype

Caused by aberration

In(2L)dpp^s5

Cytology

Description

Breakpoint allele.

(St. Johnston et al., 1990)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | larval stage (with dpp^s22)

(Stultz et al., 2005)

lethal | pharate adult stage (with dpp^s22)

(Stultz et al., 2005)

lethal | recessive

(Segal and Gelbart, 1985)

lethal - all die before end of larval stage

(St. Johnston et al., 1990)

lethal - all die before end of larval stage (with dpp^s3)

(Stultz et al., 2005)

lethal - all die before end of larval stage (with dpp^s7)

(Stultz et al., 2005)

lethal - all die before end of larval stage (with dpp^s11)

(Stultz et al., 2005)

lethal - all die before end of larval stage (with dpp^s12)

(Stultz et al., 2005)

lethal - all die before end of larval stage (with dpp^s13)

(Stultz et al., 2005)

lethal - all die before end of larval stage (with dpp^s20)

(Stultz et al., 2005)

some die during larval stage

(St. Johnston et al., 1990)

some die during larval stage (with dpp^s3)

(Stultz et al., 2005)

some die during larval stage (with dpp^s7)

(Stultz et al., 2005)

some die during larval stage (with dpp^s11)

(Stultz et al., 2005)

some die during larval stage (with dpp^s12)

(Stultz et al., 2005)

some die during larval stage (with dpp^s13)

(Stultz et al., 2005)

some die during larval stage (with dpp^s20)

(Stultz et al., 2005)

viable (with dpp^s6)

(Stultz et al., 2005)

visible (with dpp^s6)

(Stultz et al., 2005)

visible (with dpp^s11)

(Stultz et al., 2005)

visible | dominant

(Segal and Gelbart, 1985)

Phenotype Manifest In

adult head capsule (with dpp^s11)

(Stultz et al., 2005)

wing (with dpp^s11)

(Stultz et al., 2005)

Detailed Description

Statement

Reference

Adult dpp^s5/dpp^s22 escapers have wing and head capsule defects.

45% of dpp^s5/dpp^s11 animals develop as adults with head capsule and wing defects, while the remaining 55% die as larvae.

(Stultz et al., 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Mad^D14, dpp^s5 has visible | dominant phenotype

(Chen et al., 1998)

Mad^D15, dpp^s5 has visible | dominant phenotype

(Chen et al., 1998)

Mad^D24, dpp^s5 has visible | dominant phenotype

(Chen et al., 1998)

Mad^D3, dpp^s5 has visible | dominant phenotype

(Chen et al., 1998)

dpp^s5, gbb^D20 has visible | dominant phenotype

(Chen et al., 1998)

dpp^s5, gbb^D4 has visible | dominant phenotype

(Chen et al., 1998)

dpp^s5, gbb^D8 has visible | dominant phenotype

(Chen et al., 1998)

E(tkv)D1^D1, dpp^s5 has visible | dominant phenotype

(Chen et al., 1998)

E(tkv)D2^D2, dpp^s5 has visible | dominant phenotype

(Chen et al., 1998)

Phenotype Manifest In

NOT suppressed by

Statement

Reference

dpp^s5 has wing vein phenotype, non-suppressible by tkv⁴

(Penton et al., 1994)

dpp^s5 has wing vein phenotype, non-suppressible by tkv⁵

(Penton et al., 1994)

dpp^s5 has wing vein phenotype, non-suppressible by tkv⁴²⁷

(Penton et al., 1994)

dpp^s5 has wing vein phenotype, non-suppressible by Df(2L)tkv2

(Penton et al., 1994)

Other

Statement

Reference

dpp^s5, shn¹ has wing vein L4 phenotype

(Staehling-Hampton et al., 1995)

dpp^s5, shn¹ has wing vein phenotype

(Staehling-Hampton et al., 1995)

Additional Comments

Genetic Interactions

Statement

Reference

Double heterozygotes with E(tkv)D1^D1, E(tkv)D2^D2, Mad^D3, Mad^D15, Mad^D24, Mad^D14, gbb^D4, gbb^D8 or gbb^D20 may show imaginal disc development defects. No interaction with tkv⁶, tkv^D17 or Mad^D16 is seen in double heterozygous flies.

(Chen et al., 1998)

shn¹/dpp^s5 flies have a terminal gap at the end of the fourth longitudinal vein.

(Staehling-Hampton et al., 1995)

tkv⁴, tkv⁵, tkv⁷, tkv⁴²⁷ and Df(2L)tkv2 fail to complement dpp short vein alleles for the wing vein defect.

(Penton et al., 1994)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

dpp^s5 is rescued by dpp^7191.lacZ

(Penton et al., 1994)

Comments

The wing vein phenotype is rescued by the transgene carrying dpp^{7191.T:Ecol\lacZ}.

(Penton et al., 1994)

Belongs to the shv-lnc class alleles. Fails to fully complement disk region mutants.

(St. Johnston et al., 1990)

Allele class: shv-lnc

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

dpp^s5

(Stultz et al., 2005)

shv^S5

(Segal and Gelbart, 1985)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

Open Close