FlyBase Allele Report: Dmel\Mad[D3]

General Information

Symbol

Dmel\Mad^D3

Species

D. melanogaster

Name

FlyBase ID

FBal0090605

Feature type

allele

Associated gene

Dmel\Mad

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl nitrosourea

Nature of the Allele

Allele class

Mutagen

ethyl nitrosourea

(Chen et al., 1998)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Chen et al., 1998)

Phenotype Manifest In

Detailed Description

Statement

Reference

Lethal in transheterozygous combination with Mad^P1.

(Chen et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Mad^D3, Med⁴ has visible | dominant phenotype

(Chen et al., 1998)

Mad^D3, tkv⁶ has visible | dominant phenotype

(Chen et al., 1998)

Mad^D3, tkv⁶ has visible | recessive phenotype

(Chen et al., 1998)

Mad^D3, put¹³⁵ has visible | dominant phenotype

(Chen et al., 1998)

Mad^D3, dpp^s5 has visible | dominant phenotype

(Chen et al., 1998)

Df(2L)tkv2, Mad^D3 has visible | dominant phenotype

(Chen et al., 1998)

Mad^D3, shn¹ has visible | dominant phenotype

(Chen et al., 1998)

Phenotype Manifest In

Other

Statement

Reference

Mad^D3, tkv⁶ has scutum phenotype

(Chen et al., 1998)

Mad^D3, tkv⁶ has leg phenotype

(Chen et al., 1998)

Additional Comments

Genetic Interactions

Statement

Reference

Mad^D3 dominantly enhances the tkv⁶ phenotype; tkv⁶ homozygotes have a normal notum and legs, but the presence of one copy of Mad^D3 results in defects in the notum and legs. Double heterozygotes with Df(2L)tkv2, dpp^s5, shn¹, Med⁴ or put¹³⁵ may show imaginal disc development defects. No interaction with sax⁵ is seen in double heterozygous flies.

(Chen et al., 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: Dominant enhancer of the tkv⁶ phenotype. Induced on: tkv⁶.

(Chen et al., 1998)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

(Chen et al., 1998)

Mad^D3

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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