YA, fs(1)M12, EG:95B7.4 , fs(1)73, Young Arrest
Please see the JBrowse view of Dmel\fs(1)Ya for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.50
2.4 (northern blot)
There is only one protein coding transcript and one polypeptide associated with this gene
708 (aa); 112 (kD observed); 91 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\fs(1)Ya using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
fs(1)Ya protein is detected in mature eggs and embryos but not in adult males, females or ovaries. Its translation is independent of fertilization. fs(1)Ya protein persists throughout embryogenesis with its levels gradually decreasing to barely detectable in 24hr embryos. The level of protein does not decrease in unfertilized eggs for at least 8 hrs.
JBrowse - Visual display of RNA-Seq signals
View Dmel\fs(1)Ya in JBrowsePlease Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
fs(1)Ya protein is capable of associating with decondensed chromatin.
The fs(1)Ya protein might interact with itself, either directly or indirectly.
Molecular and phenotypic analysis of mutant alleles suggests that fs(1)Ya function is required during and after egg maturation to facilitate proper chromatin condensation, rather than to allow a lamin-containing nuclear envelope to form.
Lack of the fs(1)Ya gene product causes homozygous females to arrest development at the syncytial cleavage stage.
fs(1)Ya gene product is required for nuclear divisions.
Source for identity of: fs(1)Ya CG2707