FB2024_03 , released June 25, 2024
Allele: Dmel\Cdk1GT-000294
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General Information
Symbol
Dmel\Cdk1GT-000294
Species
D. melanogaster
Name
FlyBase ID
FBal0159417
Feature type
allele
Associated gene
Dmel\Cdk1
Associated Insertion(s)
P{GT1}Cdk1GT-000294
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Ryder, 2004.9.23)
Progenitor genotype
Associated Insertion(s)
P{GT1}Cdk1GT-000294
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{GT1}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      No sleep defects are observed in Cdk1GT-000294 mutant heterozygotes.

      (Afonso et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Cdk1[+]/Cdk1GT-000294 is a suppressor | partially of abnormal sleep phenotype of taras132/tarae01264

      (Afonso et al., 2015)
      NOT Suppressor of
      Statement
      Reference

      Cdk1[+]/Cdk1GT-000294 is a non-suppressor of abnormal sleep | dominant phenotype of CycAC8LR1

      (Afonso et al., 2015)

      Cdk1[+]/Cdk1GT-000294 is a non-suppressor of abnormal sleep phenotype of incf00285

      (Afonso et al., 2015)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      One copy of Cdk1GT-000294 substantially suppresses the sleep defects seen in taras132/tarae01264 mutant flies.

      One copy of Cdk1GT-000294 does not suppress the sleep defects seen in incf00285 mutant flies.

      One copy of Cdk1GT-000294 does not suppress the sleep defects seen in CycAC8LR1 mutant flies.

      (Afonso et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Cdk1B47

      (Roote, 2004.11.9)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Cdk1GT-000294
      (Afonso et al., 2015)
      cdc2GT-000294
      Name Synonyms
      Secondary FlyBase IDs
        References (3)