FlyBase Allele Report: Dmel\chm[14]

General Information

Symbol

Dmel\chm¹⁴

Species

D. melanogaster

Name

FlyBase ID

FBal0137288

Feature type

allele

Associated gene

Dmel\chm

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Grienenberger et al., 2002)

Progenitor genotype

P{lacW}muc209.6

(Grienenberger et al., 2002)

Cytology

Description

The chm coding region is deleted from the P{lacW}muc209.6 insertion site to a in the last intron, removing exon three and the 3' UTR.

(Grienenberger et al., 2002)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

adult thorax | pharate adult stage

(Miotto et al., 2006)

Detailed Description

Statement

Reference

Homozygotes die during late pupal stages. Mutant pharate adults have defects including a cleft of variable depth and width along the thorax midline.

(Miotto et al., 2006)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

chm¹⁴/chm[+] is a suppressor of increased cell death phenotype of hep^CA

(Miotto et al., 2006)

chm¹⁴/chm[+] is a suppressor of visible | dominant phenotype of hep^CA

(Miotto et al., 2006)

chm¹⁴/chm[+] is a suppressor of visible | dominant phenotype of sd^SG29.1

(Miotto et al., 2006)

Other

Statement

Reference

chm¹⁴, puc^E69/puc[+] has viable phenotype

(Miotto et al., 2006)

chm¹⁴/chm[+], puc^E69 has viable phenotype

(Miotto et al., 2006)

Phenotype Manifest In

Enhanced by

Statement

Reference

chm¹⁴ has adult thorax | pharate adult stage phenotype, enhanceable by hep⁷⁵/hep[+]

(Miotto et al., 2006)

chm¹⁴ has adult thorax | pharate adult stage phenotype, enhanceable by kay¹/kay[+]

(Miotto et al., 2006)

chm¹⁴ has adult thorax | pharate adult stage phenotype, enhanceable by kay[+]/kay²

(Miotto et al., 2006)

chm¹⁴ has larval abdominal segment 5 | ectopic phenotype, enhanceable by Pc¹⁵/Abd-B^Mcp-B116

(Grienenberger et al., 2002)

chm¹⁴ has larval abdominal segment 4 phenotype, enhanceable by Pc¹⁵/Abd-B^Mcp-B116

(Grienenberger et al., 2002)

NOT Enhanced by

Statement

Reference

chm¹⁴ has adult thorax | pharate adult stage phenotype, non-enhanceable by HDAC4[+]/HDAC4^KG05226

(Miotto et al., 2006)

chm¹⁴ has adult thorax | pharate adult stage phenotype, non-enhanceable by Jra^IA109/Jra[+]

(Miotto et al., 2006)

chm¹⁴ has adult thorax | pharate adult stage phenotype, non-enhanceable by Sir2[+]/Sirt1^05327a

(Miotto et al., 2006)

chm¹⁴ has adult thorax | pharate adult stage phenotype, non-enhanceable by eco¹/eco[+]

(Miotto et al., 2006)

chm¹⁴ has adult thorax | pharate adult stage phenotype, non-enhanceable by enok¹/enok[+]

(Miotto et al., 2006)

chm¹⁴ has adult thorax | pharate adult stage phenotype, non-enhanceable by mof[+]/mof¹

(Miotto et al., 2006)

chm¹⁴ has adult thorax | pharate adult stage phenotype, non-enhanceable by nej[+]/nej³

(Miotto et al., 2006)

Suppressed by

Statement

Reference

chm¹⁴ has adult thorax | pharate adult stage phenotype, suppressible by puc^E69/puc[+]

(Miotto et al., 2006)

chm¹⁴ has adult thorax | pharate adult stage phenotype, suppressible by HDAC1⁰⁴⁵⁵⁶/Rpd3[+]

(Miotto et al., 2006)

NOT suppressed by

Statement

Reference

chm¹⁴ has adult thorax | pharate adult stage phenotype, non-suppressible by HDAC4[+]/HDAC4^KG05226

(Miotto et al., 2006)

chm¹⁴ has adult thorax | pharate adult stage phenotype, non-suppressible by Scer\GAL4^MZ980/Jra^UAS.cEa

(Miotto et al., 2006)

chm¹⁴ has adult thorax | pharate adult stage phenotype, non-suppressible by Sir2[+]/Sirt1^05327a

(Miotto et al., 2006)

chm¹⁴ has adult thorax | pharate adult stage phenotype, non-suppressible by eco¹/eco[+]

(Miotto et al., 2006)

chm¹⁴ has adult thorax | pharate adult stage phenotype, non-suppressible by enok¹/enok[+]

(Miotto et al., 2006)

chm¹⁴ has adult thorax | pharate adult stage phenotype, non-suppressible by Scer\GAL4^MZ980/Jra^UAS.cEa/kay^UAS.cEa

(Miotto et al., 2006)

chm¹⁴ has adult thorax | pharate adult stage phenotype, non-suppressible by Scer\GAL4^MZ980/kay^UAS.cEa

(Miotto et al., 2006)

chm¹⁴ has adult thorax | pharate adult stage phenotype, non-suppressible by mof[+]/mof¹

(Miotto et al., 2006)

chm¹⁴ has adult thorax | pharate adult stage phenotype, non-suppressible by nej[+]/nej³

(Miotto et al., 2006)

Enhancer of

Statement

Reference

chm¹⁴/Pc¹⁵ is an enhancer of larval abdominal segment 4 phenotype of Abd-B^Mcp-B116

(Grienenberger et al., 2002)

chm¹⁴/Pc¹⁵ is an enhancer of larval abdominal segment 5 | ectopic phenotype of Abd-B^Mcp-B116

(Grienenberger et al., 2002)

chm¹⁴/Abd-B^Mcp-B116 is an enhancer of larval abdominal segment 4 phenotype of Pc¹⁵

(Grienenberger et al., 2002)

chm¹⁴ is an enhancer of larval abdominal segment 4 phenotype of Pc¹⁵

(Grienenberger et al., 2002)

chm¹⁴ is an enhancer of larval abdominal segment 5 | ectopic phenotype of Pc¹⁵

(Grienenberger et al., 2002)

chm¹⁴ is an enhancer of metathoracic leg phenotype of Pc¹⁵

(Grienenberger et al., 2002)

chm¹⁴ is an enhancer of sex comb | ectopic phenotype of Pc¹⁵

(Grienenberger et al., 2002)

chm¹⁴/Abd-B^Mcp-B116 is an enhancer of larval abdominal segment 5 | ectopic phenotype of Pc¹⁵

(Grienenberger et al., 2002)

chm¹⁴ is an enhancer of larval abdominal segment 5 | ectopic phenotype of Abd-B^Mcp-B116

(Grienenberger et al., 2002)

chm¹⁴ is an enhancer of larval abdominal segment 4 phenotype of Abd-B^Mcp-B116

(Grienenberger et al., 2002)

chm¹⁴ is an enhancer of larval abdominal segment 5 | ectopic phenotype of ph-p⁴¹⁰

(Grienenberger et al., 2002)

chm¹⁴ is an enhancer of larval abdominal segment 4 phenotype of ph-p⁴¹⁰

(Grienenberger et al., 2002)

Suppressor of

Statement

Reference

chm¹⁴/chm[+] is a suppressor of wing phenotype of hep^CA

(Miotto et al., 2006)

Additional Comments

Genetic Interactions

Statement

Reference

The severity of the thoracic cleft seen in chm¹⁴ pharate adults is enhanced by heterozygosity for one of hep⁷⁵, kay² or kay¹ and suppressed by heterozygosity for one of Rpd3⁰⁴⁵⁵⁶ or puc^E69.

(Miotto et al., 2006)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

chm¹⁴ is rescued by chm^UAS.cMa/Scer\GAL4^MZ980

(Miotto et al., 2006)

chm¹⁴ is rescued by chm^hs.PG

(Grienenberger et al., 2002)

Not rescued by

chm¹⁴ is not rescued by chm^G680.hs

(Grienenberger et al., 2002)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

chm¹⁴

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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