FlyBase Allele Report: Dmel\Abd-B[Mcp-B116]

General Information

Symbol

Dmel\Abd-B^Mcp-B116

Species

D. melanogaster

Name

FlyBase ID

FBal0063641

Feature type

allele

Associated gene

Dmel\Abd-B

Associated Insertion(s)

Carried in Construct

Also Known As

Mcp^B116

Key Links

Allele class

gain of function allele

Mutagen

X ray

Nature of the Allele

Allele class

gain of function allele

(Karch et al., 1994)

Mutagen

X ray

(Karch et al., 1994)

Progenitor genotype

Cytology

Description

The deletion uncovers the nuclease hypersensitive region.

(Muller et al., 1999)

900bp deletion, partially removing a silencer element MCP725.

(Busturia et al., 1997)

Lesion in the Mcp region of the bithorax complex. Deletion of 1kb between positions +95 and +96kb.

(Karch et al., 1994)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible | dominant

(Karch et al., 1994)

Phenotype Manifest In

abdominal segment 4

(Karch et al., 1994)

larval abdominal segment 4

(Grienenberger et al., 2002)

larval abdominal segment 5 | ectopic

(Grienenberger et al., 2002)

Detailed Description

Statement

Reference

Heterozygous animals have a strong transformation of the fourth abdominal segment into the fifth - patches of pigmentation are seen in the anterior part of A4.

(Grienenberger et al., 2002)

A4 is transformed to A5 identity and is a darkly pigmented.

(Karch et al., 1994)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Abd-B^Mcp-B116 has larval abdominal segment 4 phenotype, enhanceable by chm¹⁴/Pc¹⁵

(Grienenberger et al., 2002)

Abd-B^Mcp-B116 has larval abdominal segment 5 | ectopic phenotype, enhanceable by chm¹⁴/Pc¹⁵

(Grienenberger et al., 2002)

Abd-B^Mcp-B116 has larval abdominal segment 5 | ectopic phenotype, enhanceable by chm¹⁴

(Grienenberger et al., 2002)

Abd-B^Mcp-B116 has larval abdominal segment 4 phenotype, enhanceable by chm¹⁴

(Grienenberger et al., 2002)

Enhancer of

Statement

Reference

chm¹⁴/Abd-B^Mcp-B116 is an enhancer of larval abdominal segment 4 phenotype of Pc¹⁵

(Grienenberger et al., 2002)

chm¹⁴/Abd-B^Mcp-B116 is an enhancer of larval abdominal segment 5 | ectopic phenotype of Pc¹⁵

(Grienenberger et al., 2002)

Pc¹⁵/Abd-B^Mcp-B116 is an enhancer of larval abdominal segment 5 | ectopic phenotype of chm¹⁴

(Grienenberger et al., 2002)

Pc¹⁵/Abd-B^Mcp-B116 is an enhancer of larval abdominal segment 4 phenotype of chm¹⁴

(Grienenberger et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Abd-B^Mcp-B116

Mcp^B116

(Singh and Mishra, 2015, Kyrchanova and Georgiev, 2010, Grienenberger et al., 2002, Grienenberger et al., 2002, Muller et al., 1999, Busturia et al., 1997, Karch et al., 1994)

Name Synonyms

Secondary FlyBase IDs

References (8)

Report Sections

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