Amino acid replacement: ??term.
mitosis & nuclear chromosome
mitosis & nuclear chromosome (with ecoEY00297)
Homozygous larval brains show an increased mitotic index (2.07) compared to wild type (1.04). 76% of the mitotic cells are in prometaphase/metaphase compared to 88% in wild type. 96% of anaphases show abnormalities, 46% of mitotic cells have overcondensed chromosomes and 81% of prometaphase/metaphase cells show precocious sister chromatid separation (PSCS). Metaphase figures show high levels of aneuploidy and rare polyploid cells are seen. Many chromosomes are still able to congress to the metaphase plate, but this congression is not normal; small chromatin entities are situated away from the metaphase plate in a large fraction of the cells and the chromosomes at the metaphase plate are less tightly arrayed than in wild type. Sister centromeres are correctly oriented towards the poles but are further apart than normal. Hemizygous larval brains show a reduced mitotic index (0.73) compared to wild type (1.04). 86% of the mitotic cells are in prometaphase/metaphase compared to 88% in wild type. 100% of anaphases show abnormalities, 75% of mitotic cells have overcondensed chromosomes and 96% of prometaphase/metaphase cells show precocious sister chromatid separation (PSCS). eco1/ecoEY00297 larval brains show a reduced mitotic index (0.80) compared to wild type (1.04). 78% of the mitotic cells are in prometaphase/metaphase compared to 88% in wild type. 19% of anaphases show abnormalities, 31% of mitotic cells have overcondensed chromosomes and 32% of prometaphase/metaphase cells show precocious sister chromatid separation (PSCS).
eco1/eco[+] is a non-enhancer of adult thorax | pharate adult stage phenotype of chm14
eco1/eco[+] is a non-enhancer of wing margin phenotype of ctK
eco1/eco[+] is a non-suppressor of adult thorax | pharate adult stage phenotype of chm14
eco1/eco[+] is a non-suppressor of wing margin phenotype of ctK
Sister chromatids separate prematurely in eco1 Sseunspecified double mutant larval brain cells, as they do in eco1 single mutants.