FlyBase Allele Report: Dmel\fru[M5]

General Information

Symbol

Dmel\fru^M5

Species

D. melanogaster

Name

FlyBase ID

FBal0126396

Feature type

allele

Associated gene

Dmel\fru

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Caused by aberration

Df(3R)Cha^M5

Cytology

Description

Deficiency breakpoint in fru between the P1 and P2 promoters, with the deficiency extending distally, removing the P1 promoter.

(Anand et al., 2001)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal courtship behavior | male (with fru^sat15)

(Anand et al., 2001)

abnormal courtship behavior | male (with fru^w9)

(Anand et al., 2001)

abnormal song (with fru^w12)

(Anand et al., 2001)

decreased rate of movement | male (with fru^sat15)

(Anand et al., 2001)

decreased rate of movement | male (with fru^w9)

(Anand et al., 2001)

decreased rate of movement | male (with fru^w12)

(Anand et al., 2001)

lethal (with Df(3R)fru^w24)

(Anand et al., 2001)

lethal (with fru^4-40)

(Anand et al., 2001)

male fertile (with fru^0-1)

(Anand et al., 2001)

male sterile (with fru^sat15)

(Anand et al., 2001)

male sterile (with fru^w9)

(Anand et al., 2001)

male sterile (with fru^w12)

(Anand et al., 2001)

male sterile (with fru^w27)

(Anand et al., 2001)

viable (with fru^P14)

(Anand et al., 2001, Lee et al., 2000)

viable (with fru^sat15)

(Anand et al., 2001)

Phenotype Manifest In

muscle cell of male abdominal 5 muscle (with fru^w9)

(Anand et al., 2001)

muscle cell of male abdominal 5 muscle (with fru^w12)

(Anand et al., 2001)

muscle cell of male abdominal 5 muscle (with fru^w27)

(Anand et al., 2001)

Detailed Description

Statement

Reference

fru^sat15/fru^M5 embryos have normal Fas2-positive and BP102-positive axon tracts in the central nervous system.

(Song et al., 2002)

93% of fru^0-1/fru^M5 males are fertile. 3% of fru^w27/fru^M5 males are fertile. Male-female courtship as measured by courtship index (CI) or wing extension index (WEI) is almost completely abolished in fru^w9/fru^M5 males. Male-female courtship as measured by courtship index (CI) or wing extension index (WEI) is completely abolished in fru^sat15/fru^M5 males. fru^w9/fru^M5, fru^sat15/fru^M5 or fru^w27/fru^M5 males show substantial chaining. fru^w12/fru^M5 males do not produce a courtship song even though they show a small amount of wing extension. Abdominal muscle innervation appears normal in fru^w27/fru^M5 adults.

(Anand et al., 2001)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

fru^M5

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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