FB2024_03 , released June 25, 2024
Allele: Dmel\Cam6c4
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General Information
Symbol
Dmel\Cam6c4
Species
D. melanogaster
Name
FlyBase ID
FBal0083597
Feature type
allele
Associated gene
Dmel\Cam
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Nelson et al., 1997)
Progenitor genotype
Cytology
Description

Amino acid replacement: D131N.

(Nelson et al., 1997)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:12,269,408..12,269,408 [+]
Nucleotide change:

G12269408A

Amino acid change:

D132N | Cam-PA; D132N | Cam-PB; D132N | Cam-PC; D132N | Cam-PD; D132N | Cam-PE

Reported amino acid change:

D131N

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Nelson et al., 1997)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Transheterozygous combinations with other Cam mutations produces an incompletely penetrant ectopic wing vein phenotype.

      (Nelson et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      Cam6c4, l(2)C43C43 has partially lethal phenotype

      (Nelson et al., 1997)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      In combination with l(2)C43C43 mutants exhibit markedly reduced viability.

      (Nelson et al., 1997)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Allelic series of the relative strength of the lethal mutations: Cam8t > Cam7 > Cam6c4 > Cam5 > Cam4c1 > Cam3c1.

      (Nelson et al., 1997)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Cam6c4
      Name Synonyms
      Secondary FlyBase IDs
        References (1)