FB2024_03 , released June 25, 2024
Allele: Dmel\l(2)C43C43
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General Information
Symbol
Dmel\l(2)C43C43
Species
D. melanogaster
Name
FlyBase ID
FBal0082787
Feature type
allele
Associated gene
l(2)C43
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Nelson et al., 1997)
Progenitor genotype
Cytology
Description

Mutation maps within 15kb of the Cam transcription start site.

(Nelson et al., 1997)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Most pupae do not develop past the white prepupal stage. Mutation does not affect mitotically active tissues.

      (Nelson et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Statement
      Reference

      Camunspecified, l(2)C43C43 has wing phenotype

      (Nelson et al., 1997)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Camhs.PN restores good viability, about 50%. l(2)C43C43 produces a completely penetrant lethality or markedly reduced viability with all Cam alleles. Combinations with Cam alleles also produce an incompletely penetrant wing phenotype, the entire wing blade is curved downward like a spoon. l(2)C43C43/fs(2)H47H47 mutants die during the first larval instar.

      (Nelson et al., 1997)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      l(2)C43C43
      Name Synonyms
      Secondary FlyBase IDs
        References (1)