FlyBase Allele Report: Dmel\Abd-B[iab9-65]

General Information

Symbol

Dmel\Abd-B^iab9-65

Species

D. melanogaster

Name

FlyBase ID

FBal0000138

Feature type

allele

Associated gene

Dmel\Abd-B

Associated Insertion(s)

Carried in Construct

Also Known As

iab-7⁶⁵, 65

Key Links

Allele class

loss of function allele

Mutagen

X ray

Nature of the Allele

Allele class

loss of function allele

(Boulet et al., 1991, Celniker et al., 1990)

Mutagen

X ray

(Kuhn et al., 1993, Karch et al., 1985)

Progenitor genotype

Caused by aberration

T(2;3)iab9⁶⁵

Cytology

Description

Breakpoint maps to between coordinates +163 and +165.5kb.

(Kuhn et al., 1993)

Lesion mapped to: +163-166.5 kb.

(Karch et al., 1985)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile | dominant

(Karch et al., 1985)

lethal | recessive

(Karch et al., 1985)

male sterile | dominant

(Karch et al., 1985)

visible | dominant

(Karch et al., 1985)

visible | homeotic | somatic clone

(Sanchez-Herrero and Crosby, 1988)

visible | recessive

(Kuhn et al., 1993)

Phenotype Manifest In

abdominal segment 4 | ectopic | somatic clone

(Sanchez-Herrero and Crosby, 1988)

abdominal segment 5 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

abdominal segment 6 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

abdominal segment 7 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

abdominal segment 8 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

denticle & embryonic abdominal segment 9 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

denticle | somatic clone

(Sanchez-Herrero and Crosby, 1988)

embryonic abdominal segment 8 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

embryonic abdominal segment 9 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

female terminalia

(Kuhn et al., 1993)

genitalia

(Kuhn et al., 1993)

genitalia | female | somatic clone

(Sanchez-Herrero and Crosby, 1988)

head

(Kuhn et al., 1993)

male terminalia

(Kuhn et al., 1993)

parasegment 9 | ectopic | somatic clone

(Sanchez-Herrero and Crosby, 1988)

parasegment 10 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

parasegment 11 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

parasegment 12 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

parasegment 13 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

sclerite & abdominal segment 8 & embryo | somatic clone

(Sanchez-Herrero and Crosby, 1988)

sclerite | somatic clone

(Sanchez-Herrero and Crosby, 1988)

Detailed Description

Statement

Reference

Adult homozygous males have 6 normal abdominal segments. Males and Females lack genitalia. Enhances penetrance of head defect phenotype when in trans with Abd-B^iab9-tuh-3. Heterozygotes with Abd-B^iab9-tuh-3 exhibit genital defects to a moderate degree.

(Kuhn et al., 1993)

Embryos lack the r function, as shown by their ability to complement the m^-r⁺ allele Abd-B^iab8-D14. The m function is not completely destroyed (FBrf0043917; FBrf0047933).

(Boulet et al., 1991)

A5-A8 (including female genitalia) transformed to A4 in mosaics. Embryos have extra denticles in A9, and parasegments 10-13 are transformed to parasegment 9.

(Sanchez-Herrero and Crosby, 1988)

Dominant haplo-insufficient phenotypes. Lethal or nearly lethal over Df(3R)P9 : surviving flies are completely or partially sterile.

(Karch et al., 1985)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Abd-B^Uab-1

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab9-x23-1

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab9-tuh-3

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab9-Tab

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-D15

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-D14

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-D6

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv82

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv96

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv111

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv185

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv100

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv114

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv89

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv175

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv107

(Sanchez-Herrero and Crosby, 1988)

Abd-B^M9

(Sanchez-Herrero and Crosby, 1988)

Abd-B^M7

(Sanchez-Herrero and Crosby, 1988)

Abd-B^M4

(Sanchez-Herrero and Crosby, 1988)

Abd-B^M2

(Sanchez-Herrero and Crosby, 1988)

Abd-B³⁸⁰

(Sanchez-Herrero and Crosby, 1988)

Abd-B^S2

(Sanchez-Herrero and Crosby, 1988)

Abd-B^S1

(Sanchez-Herrero and Crosby, 1988)

Abd-B^M6

(Sanchez-Herrero and Crosby, 1988)

Abd-B^M5

(Sanchez-Herrero and Crosby, 1988)

Abd-B^M3

(Sanchez-Herrero and Crosby, 1988)

Abd-B^S9

(Sanchez-Herrero and Crosby, 1988)

Abd-B^S8

(Sanchez-Herrero and Crosby, 1988)

Abd-B^S5

(Sanchez-Herrero and Crosby, 1988)

Abd-B^R

(Sanchez-Herrero and Crosby, 1988)

Abd-B^F

(Sanchez-Herrero and Crosby, 1988)

Comments

Fails to complement all mutations in the Abd-B domain. Interactions with Abd-B domain mutations may be variable and weak.

(Sanchez-Herrero and Crosby, 1988)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

R.H. Baker.

R. Baker.

(Karch et al., 1985)

Comments

m⁺ r^- mutant.

(Kuhn et al., 1993)

Abd-B m⁺r^- mutation.

(Kuhn et al., 1995)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (8)

Reported As

Symbol Synonym

(Kuhn et al., 1995, Kuhn et al., 1993)

Abd-B⁶⁵

(Estrada et al., 2002)

Abd-B^iab7-65

Abd-B^iab9-65

iab-7⁶⁵

(Estrada et al., 2002, Boulet et al., 1991, de Lorenzi et al., 1988, Sanchez-Herrero and Crosby, 1988, Karch et al., 1985)

iab7⁶⁵

iab9¹⁰⁶⁵

(Estrada et al., 2002)

iab9⁶⁵

(Mack et al., 1997)

Name Synonyms

Secondary FlyBase IDs

FBal0028677

References (9)

Report Sections

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