FB2024_03 , released June 25, 2024
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Citation
Ashburner, M. (1982). The genetics of a small autosomal region of Drosophila melanogaster containing the structural gene for Alcohol dehydrogenase. III. Hypomorphic and hypermorphic mutations affecting the expression of Hairless. Genetics 101(): 447--459.
FlyBase ID
FBrf0038053
Publication Type
Research paper
Abstract
A lethal locus (l(2)br7;35B6-10), near Adh on chromosome arm 2L of D. melanogaster, is identified with Plunkett's dominant suppressor of Hairless (H). Of eight new alleles, seven act as dominant suppressors of H, the eighth is a dominant enhancer of H. One of the suppressor alleles is both a leaky lethal and a weak suppressor of H. Confirming Nash (1970), deletions of l(2)br7 are dominant suppressors, and duplications are dominant enhancers of H. A simple model is proposed to account for the interaction of l(2)br7 and H, assuming that amorphic (or hypomorphic) alleles of l(2)br7 suppress H and that hypermorphic alleles enhance H.
PubMed ID
PubMed Central ID
PMC1201871 (PMC) (EuropePMC)
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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Genetics
    Title
    Genetics
    Publication Year
    1916-
    ISBN/ISSN
    0016-6731
    Data From Reference