FlyBase Gene Report: Dmel\Pgam2

General Information

Symbol

Dmel\Pgam2

Species

D. melanogaster

Name

Phosphoglycerate mutase 2

Annotation Symbol

CG17645

Feature Type

protein_coding_gene

FlyBase ID

FBgn0011270

Gene Model Status

Current

Stock Availability

4 publicly available

Enzyme Name (EC)

phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) (5.4.2.11)

bisphosphoglycerate mutase (5.4.2.4)

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

Pglym87, Pglym

Key Links

Genomic Location

Cytogenetic map

87B3-87B3

Sequence location

3R:12,231,645..12,232,729 [-]

Recombination map

3-52

RefSeq locus

NT_033777 REGION:12231645..12232729

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (7 terms)

Molecular Function (3 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

enables 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity

inferred from sequence or structural similarity with UniProtKB:P18669

(Gene Ontology Curators, 2002-)

enables bisphosphoglycerate mutase activity

inferred from sequence or structural similarity with UniProtKB:P18669

(Gene Ontology Curators, 2002-)

enables intramolecular phosphotransferase activity

inferred from electronic annotation with InterPro:IPR005952

(InterPro Project Members, 2004-)

Biological Process (3 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

involved_in canonical glycolysis

inferred from sequence or structural similarity with UniProtKB:Q9VAN7

(Gene Ontology Curators, 2002-)

involved_in gluconeogenesis

inferred from sequence or structural similarity with UniProtKB:Q9DBJ1

(Gene Ontology Curators, 2002-)

involved_in glycolytic process

inferred from electronic annotation with InterPro:IPR005952

(InterPro Project Members, 2004-)

Cellular Component (1 term)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

is_active_in cytosol

inferred from sequence or structural similarity with UniProtKB:Q9DBJ1

(Gene Ontology Curators, 2002-)

Gene Group (FlyBase)

INTRAMOLECULAR PHOSPHOTRANSFERASES

Protein Family (UniProt)

Protein Signatures (InterPro)

Catalytic Activity (EC/Rhea)

bisphosphoglycerate mutase activity

(2R)-3-phospho-glyceroyl phosphate = (2R)-2,3-bisphosphoglycerate + H(+) (5.4.2.4)

RHEA 17765: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity

(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate (5.4.2.11)

Summaries

Gene Group (FlyBase)

INTRAMOLECULAR PHOSPHOTRANSFERASES -: Intramolecular phosphotransferases catalyze the transfer of a phosphate group from one part of a molecule to another. (Adapted from FBrf0238665.)

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Pgam2 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VGB6)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.39

Gene model reviewed during 5.47

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

retrogene

(dos Santos, 2014, Bai et al., 2007, Langille and Clark, 2007, Currie and Sullivan, 1994)

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Pgam2-RA

FBtr0082620

NM_143784

1085

292

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Pgam2-PA

FBpp0082089

33.0

292

9.34

Q9VGB6

NP_652041

AAF54767

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Pgam2 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Pglym87_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

5.16

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

spermatogenesis

elongation stage spermatid | distal

(Barreau et al., 2008)

primary spermatocyte

Comment: weak

(Barreau et al., 2008)

Additional Descriptive Data

Pgam2 transcripts are detected at low levels in primary spermatocytes and are barely detected in early elongation spermatids. Robust signals are detected in more elongated spermatids at the distal ends. Transcripts localize into a ball shape at the ends of spermatids bundles, trailing away proximally to a less abundant, speckled distribution (called a comet pattern).

(Barreau et al., 2008)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

day 5 of adulthood & male -- day 7 of adulthood & male

spermatozoon

(Wasbrough et al., 2010, Dorus et al., 2006)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Pgam2 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Pgam2

View exonic expression by tissue for Dmel\Pgam2

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0011270

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

46246/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0011270

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0011270

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0011270

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG17645

Flygut - An atlas of the Drosophila adult midgut

FBgn0011270

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 1 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Pgam2

Transgenic constructs containing regulatory region of Pgam2

Aberrations (Deficiencies and Duplications) ( 2 )

Inferred from experimentation ( 2 )

Gene disrupted in

Df(3R)Exel6162

(Ryder, 2004.4.26)

Df(3R)Exel7313

(Ryder, 2004.4.26)

Inferred from location ( 0 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Pgam2^GD9433

viable, with Scer\GAL4^pnr-MD237

Pgam2^GD9433

viable, with Scer\GAL4^tin.CΔ4

Pgam2^GD9433

Other Phenotypes

Allele

abnormal flight, with Scer\GAL4^Mef2.PR

Pgam2^GD9433

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (11)

Hsap\PGAM2

14 of 14

Yes

Hsap\PGAM1

13 of 14

Hsap\PGAM4

11 of 14

Yes

Hsap\BPGM

7 of 14

Yes

Hsap\TIGAR

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (9)

Rnor\Pgam2

14 of 14

Yes

Rnor\Pgam1

13 of 14

Rnor\LOC691137

8 of 14

Rnor\Bpgm

7 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (8)

Mmus\Pgam2

14 of 14

Yes

Mmus\Pgam1

13 of 14

Mmus\Bpgm

6 of 14

Yes

Mmus\Tigar

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (8)

Xtro\pgam2

11 of 13

Yes

Xtro\pgam1

7 of 13

Xtro\bpgm

6 of 13

Yes

Xtro\c1galt1c1

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Danio rerio (Zebrafish) (14)

Drer\pgam2

14 of 14

Yes

Drer\pgam1a

13 of 14

Drer\pgam1b

13 of 14

Drer\bpgm

7 of 14

Yes

Drer\tigara

2 of 14

Yes

Drer\tigarb

2 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (4)

Cele\pfkb-1.1

1 of 14

Yes

Cele\pfkb-1.2

1 of 14

Yes

Cele\T07F12.1

1 of 14

Yes

Cele\Y18H1A.4

1 of 14

Yes

Anopheles gambiae (African malaria mosquito) (5)

Agam\AgaP_AGAP001420

8 of 12

Yes

6 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (10)

Atha\AT1G22170

11 of 13

Yes

Atha\PGM

11 of 13

Yes

Atha\AT5G22620

3 of 13

Yes

Atha\AT3G50520

2 of 13

Yes

Atha\AT5G04120

2 of 13

Yes

Atha\AT1G12850

1 of 13

Atha\AT3G05170

1 of 13

Yes

Atha\AT4G38370

1 of 13

Yes

Atha\F2KP

1 of 13

Atha\MEF14

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (7)

Scer\GPM1

12 of 13

Yes

Scer\GPM2

4 of 13

Scer\GPM3

3 of 13

Scer\SHB17

3 of 13

Yes

Scer\YOR283W

2 of 13

Yes

Scer\FBP26

1 of 13

Scer\YNL108C

1 of 13

Schizosaccharomyces pombe (Fission yeast) (5)

Spom\gpm1

11 of 12

Yes

Spom\SPAC1687.21

2 of 12

Yes

Spom\SPCC1620.13

2 of 12

Yes

Spom\SPAC5H10.03

1 of 12

Yes

Spom\SPAC732.02c

1 of 12

Escherichia coli (enterobacterium) (3)

Ecol\gpmA

11 of 11

Yes

Ecol\cobC

1 of 11

Ecol\ytjC

1 of 11

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Pgam2. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (4)

12 of 13

10 of 13

1 of 13

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 1 )

Human Ortholog

Disease

Evidence

References

BPGM; bisphosphoglycerate mutase

model of familial erythrocytosis 8

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

PGAM2; phosphoglycerate mutase 2

14 of 14

612931

GLYCOGEN STORAGE DISEASE X; GSD10

PGAM1; phosphoglycerate mutase 1

13 of 14

172250

PGAM4; phosphoglycerate mutase family member 4

11 of 14

300567

BPGM; bisphosphoglycerate mutase

7 of 14

613896

ERYTHROCYTOSIS, FAMILIAL, 8; ECYT8

familial erythrocytosis 8

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Show neighbor-neighbor interactions:

Off

Show/hide secondary interactors
(data from AllianceMine provided by esyN)

Select Layout:

Force Directed

Circle

Concentric

Legend:

Protein

RNA

Selected Interactor(s)

Other Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Pgam2 - CG17027

experimental knowledge based

(Guruharsha et al., 2011)

Pgam2 - Mlc-c

experimental knowledge based

(Guruharsha et al., 2011)

Pgam2 - Pgam1

experimental knowledge based

(Guruharsha et al., 2011)

Pgam2 - zip

experimental knowledge based

(Guruharsha et al., 2011)

Summary of Genetic Interactions

esyN Network Diagram

Other Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

70148

DroID - A comprehensive database of gene and protein interactions.

FBgn0011270

MIST (protein-protein) - An integrated Molecular Interaction Database

46246

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.

External Data

Linkouts

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-52

Cytogenetic map

87B3-87B3

Sequence location

3R:12,231,645..12,232,729 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

87B3-87B3

Limits computationally determined from genome sequence between P{EP}Lk6^EP886 and P{PZ}svp⁰⁷⁸⁴²

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

87B4-87B5

(Currie, 1994)

Experimentally Determined Recombination Data

Location

3-52

(FlyBase, 2016)

3-49.3

(Comeron et al., 2012)

(Currie, 1994)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (4)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

51939

y¹ v¹; P{TRiP.HMC03367}attP40/CyO

NIG-Fly

HMC03367

y¹ v¹; P{TRiP.HMC03367}attP40/CyO

VDRC

v330387

P{VSH330387}attP40

v41658

w¹¹¹⁸; P{GD9433}v41658

Genomic Clones (20)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (32)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

GH28416

Other clones

DPiM_GH28416

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0011270

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0011270

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Comparison of the gene structure of Pglym78 and Pglym87 suggests that Pglym87 arose through retrotransposition from a Pglym78 transcript, additional more complex mechanisms may have played some role in the origin of Pglym87. Structural properties suggest Pglym87 is a pseudogene with a peculiar rate and pattern of evolution, aspects of Pglym87 molecular evolution suggest it might be a functional gene having puzzling aspects in its structure.

(Currie and Sullivan, 1994)

Relationship to Other Genes

Source for database merge of

Source for merge of: Pglym87 CG17645

(Bayraktaroglu, 2000.11.2)

Additional comments

The Pglym87 gene may have been derived from the Pglym78 gene by retroposition.

(Bai et al., 2007, Langille and Clark, 2007, Currie and Sullivan, 1994)

Nomenclature History

Source for database identify of

Source for identity of: Pgam2 Pglym87

(FlyBase, 2017-)

Nomenclature comments

Renamed from 'Pglym87' to 'Pgam2' to (i) remove the species-specific reference to cytogenetic location; (ii) use the more widely used nomenclature prefix for this gene across species.

(FlyBase, 2017-)

Etymology

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

CG17645

(Meadows, 2017.9.14, Ni et al., 2010.12.1, Barreau et al., 2008, Mount, 2001.8.14)

Pgam2

Pglym

(Nirala et al., 2013, Eanes, 2011)

Pglym87

(Bamgbose and Tulin, 2024, Zheng et al., 2023, Hunt and Demontis, 2022, Zang et al., 2015, dos Santos, 2014, Yasunaga et al., 2014, Doggett et al., 2011, Wasbrough et al., 2010, Barreau et al., 2008, Bai et al., 2007, Bai et al., 2007, Geng and MacDonald, 2007, Langille and Clark, 2007, Langille and Clark, 2007, Dorus et al., 2006, Manh et al., 2005)

pglym87

(Currie, 1994, Currie and Sullivan, 1994)

Name Synonyms

Pglym87

Phosphoglycerate mutase 2

Phosphoglyceromutase 87

Secondary FlyBase IDs

FBgn0038004

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 56 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

46246

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VGB6

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VGB6

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0011270

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

46246/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0011270

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0011270

FlyMine - An integrated database for Drosophila genomics

FBgn0011270

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG17645

MARRVEL_MODEL - MARRVEL (model organism gene)

46246

Linkouts

BioGRID - A database of protein and genetic interactions.

70148

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0011270

DroID - A comprehensive database of gene and protein interactions.

FBgn0011270

DRSC - Results frm RNAi screens

FBgn0011270

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Pglym87_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0011270

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0011270

FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG17645

Flygut - An atlas of the Drosophila adult midgut

FBgn0011270

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0011270

KEGG Metabolic Pathways - A collection of manually drawn metabolic pathway maps representing knowledge of molecular interaction, reaction and relation networks.

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

MIST (protein-protein) - An integrated Molecular Interaction Database

46246

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Reactome Metabolic Pathways - An open-source, open access, manually curated and peer-reviewed metabolic pathway database.

References (56)

The following external sites may use different assemblies or annotations than FlyBase.

5.16

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