FB2024_03 , released June 25, 2024
Allele: Dmel\mrtF931
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General Information
Symbol
Dmel\mrtF931
Species
D. melanogaster
Name
FlyBase ID
FBal0344192
Feature type
allele
Associated gene
Dmel\mrt
Associated Insertion(s)
P{Mae-UAS.6.11}mrtF931
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{Mae-UAS.6.11}mrtF931
    Cytology
    Description

    Insertion of a P{Mae-UAS.6.11} element, 140bp upstream of the transcription start site of the mrt-RA isoform.

    (Yao et al., 2018)
    Allele components
    Component
    Use(s)
    Inserted element
    P{Mae-UAS.6.11}
    Regulatory region(s)
    UAS
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Expressing mrtF931 under the control of Scer\GAL4ppl.PU induces significantly larger lipid droplets in the larval fat body from second instar onwards, as compared to controls; this phenotype is more severe upon the addition of mrtEY10964; large lipid droplets in the larval fat body are observed in either fed or starved conditions and isolated lipid droplet coalesce more frequently, as compared to controls. These individuals still accumulate lipid droplets in third instar larval oenocytes, as compared to controls.

        (Yao et al., 2018)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhanced by
        Suppressed by
        NOT suppressed by
        NOT Enhancer of
        Statement
        Reference

        mrtF931, Scer\GAL4ppl.PU is a non-enhancer of abnormal size | larval stage phenotype of Lsd-1HMC05894, Scer\GAL4ppl.PU

        (Yao et al., 2018)
        Phenotype Manifest In
        Enhanced by
        Suppressed by
        NOT suppressed by
        Statement
        Reference

        Scer\GAL4ppl.PU, mrtF931 has embryonic/larval fat body | larval stage phenotype, non-suppressible by pzgEY11005/Scer\GAL4ppl.PU

        (Yao et al., 2018)

        Scer\GAL4ppl.PU, mrtF931 has lipid droplet | larval stage phenotype, non-suppressible by pzgEY11005/Scer\GAL4ppl.PU

        (Yao et al., 2018)

        Scer\GAL4ppl.PU, mrtF931 has embryonic/larval fat body | larval stage phenotype, non-suppressible by Dgat2GD16204, Scer\GAL4ppl.PU

        (Yao et al., 2018)

        Scer\GAL4ppl.PU, mrtF931 has lipid droplet | larval stage phenotype, non-suppressible by Dgat2GD16204, Scer\GAL4ppl.PU

        (Yao et al., 2018)

        Scer\GAL4ppl.PU, mrtF931 has embryonic/larval fat body | larval stage phenotype, non-suppressible by Gpat4KK108132, Scer\GAL4ppl.PU

        (Yao et al., 2018)

        Scer\GAL4ppl.PU, mrtF931 has lipid droplet | larval stage phenotype, non-suppressible by Gpat4KK108132, Scer\GAL4ppl.PU

        (Yao et al., 2018)

        Scer\GAL4ppl.PU, mrtF931 has embryonic/larval fat body | larval stage phenotype, non-suppressible by Pcyt1GS13579, Scer\GAL4ppl.PU

        (Yao et al., 2018)

        Scer\GAL4ppl.PU, mrtF931 has lipid droplet | larval stage phenotype, non-suppressible by Pcyt1GS13579, Scer\GAL4ppl.PU

        (Yao et al., 2018)

        Scer\GAL4ppl.PU, mrtF931 has embryonic/larval fat body | larval stage phenotype, non-suppressible by IswiGLC01788, Scer\GAL4ppl.PU

        (Yao et al., 2018)

        Scer\GAL4ppl.PU, mrtF931 has lipid droplet | larval stage phenotype, non-suppressible by IswiGLC01788, Scer\GAL4ppl.PU

        (Yao et al., 2018)

        Scer\GAL4ppl.PU, mrtF931 has embryonic/larval fat body | larval stage phenotype, non-suppressible by Nurf-38JF01299, Scer\GAL4ppl.PU

        (Yao et al., 2018)

        Scer\GAL4ppl.PU, mrtF931 has lipid droplet | larval stage phenotype, non-suppressible by Nurf-38JF01299, Scer\GAL4ppl.PU

        (Yao et al., 2018)

        Scer\GAL4ppl.PU, mrtF931 has embryonic/larval fat body | larval stage phenotype, non-suppressible by Nurf-38GL00369, Scer\GAL4ppl.PU

        (Yao et al., 2018)

        Scer\GAL4ppl.PU, mrtF931 has lipid droplet | larval stage phenotype, non-suppressible by Nurf-38GL00369, Scer\GAL4ppl.PU

        (Yao et al., 2018)

        Scer\GAL4ppl.PU, mrtF931 has embryonic/larval fat body | larval stage phenotype, non-suppressible by Dgat2GD1854, Scer\GAL4ppl.PU

        (Yao et al., 2018)

        Scer\GAL4ppl.PU, mrtF931 has lipid droplet | larval stage phenotype, non-suppressible by Dgat2GD1854, Scer\GAL4ppl.PU

        (Yao et al., 2018)
        NOT Enhancer of
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        mrtF931 is rescued by mrtGD10947/Scer\GAL4ppl.PU

        (Yao et al., 2018)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        mrtF931
        Name Synonyms
        Secondary FlyBase IDs
          References (1)