Construct: Genomic 6.8kb NotI-XbaI fragment containing Dvir\mod(mdg4) common exons 1-4.
Dvir\mod(mdg4)t6.8 is a suppressor | partially of lethal phenotype of mod(mdg4)neo129/mod(mdg4)02
Dvir\mod(mdg4)t6.8 is a suppressor | partially of lethal | male phenotype of mod(mdg4)02/mod(mdg4)R32
Dvir\mod(mdg4)t6.8 is a suppressor of lethal | recessive phenotype of mod(mdg4)02
Dvir\mod(mdg4)t6.8 is a non-suppressor of lethal phenotype of mod(mdg4)07/mod(mdg4)02
Dvir\mod(mdg4)t6.8 is a non-suppressor of lethal | female phenotype of mod(mdg4)02/mod(mdg4)R32
One copy of Dvir\mod(mdg4)t6.8 partially rescues the lethality of mod(mdg4)02 homozygotes (10.7% viability is seen). Salivary glands and nuclei are reduced in size and show changes in chromosome morphology in these animals at the larval stage. 74.0% viability is seen in mod(mdg4)02 homozygotes carrying two copies of Dvir\mod(mdg4)t6.8. One copy of Dvir\mod(mdg4)t6.8 partially rescues the lethality of mod(mdg4)02/mod(mdg4)neo129 transheterozygotes (34% viability is seen). One copy of Dvir\mod(mdg4)t6.8 partially rescues the lethality of mod(mdg4)R32/mod(mdg4)02 transheterozygous males (52.3% viability is seen), but the lethality of mod(mdg4)R32/mod(mdg4)02 females is not rescued. One copy of Dvir\mod(mdg4)t6.8 does not suppresses the lethality of mod(mdg4)07/mod(mdg4)02 transheterozygotes.
Assayed in D.melanogaster.