FB2024_03 , released June 25, 2024
Allele: Dmel\ihoge02142
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General Information
Symbol
Dmel\ihoge02142
Species
D. melanogaster
Name
FlyBase ID
FBal0179424
Feature type
allele
Associated gene
Dmel\ihog
Associated Insertion(s)
PBac{RB}ihoge02142
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Yao et al., 2006)

hypomorphic allele - molecular evidence

(Hartman et al., 2010)
Mutagen
piggyBac activity
(Gene Disruption Project members and Exelixis, 2005)
Progenitor genotype
Associated Insertion(s)
PBac{RB}ihoge02142
Cytology
Description

PBac{RB} insertion in the 5'UTR of the iHog gene, 81bp downstream of the transcription start site.

(Yao et al., 2006)
Allele components
Component
Use(s)
Inserted element
PBac{RB}
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      ihoge02142 mutants exhibit wild-type follicle stem cell proliferation and follicle production.

      (Hartman et al., 2010)

      Paternally-provided iHoge02142 lessens the severity of the denticle belt fusions seen in embryos from either iHogKG or iHogEY maternal germ-line clones.

      (Yao et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Statement
      Reference

      ihog[+]/ihoge02142 is a non-enhancer of hyperplasia phenotype of boie01708

      (Hartman et al., 2010)
      NOT Suppressor of
      Statement
      Reference

      ihog[+]/ihoge02142 is a non-suppressor of hyperplasia phenotype of boie01708

      (Hartman et al., 2010)
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      ihog[+]/ihoge02142 is a non-enhancer of stalk follicle cell phenotype of boie01708

      (Hartman et al., 2010)

      ihog[+]/ihoge02142 is a non-enhancer of follicle cell phenotype of boie01708

      (Hartman et al., 2010)

      ihog[+]/ihoge02142 is a non-enhancer of follicle stem cell phenotype of boie01708

      (Hartman et al., 2010)
      NOT Suppressor of
      Statement
      Reference

      ihog[+]/ihoge02142 is a non-suppressor of stalk follicle cell phenotype of boie01708

      (Hartman et al., 2010)

      ihog[+]/ihoge02142 is a non-suppressor of follicle cell phenotype of boie01708

      (Hartman et al., 2010)

      ihog[+]/ihoge02142 is a non-suppressor of follicle stem cell phenotype of boie01708

      (Hartman et al., 2010)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The penetrance and severity of the follicle cell phenotypes of homozygous boie01708 flies are not affected by ihoge02142/+.

      (Hartman et al., 2010)

      iHoge02142; dlpA187 zygotic mutants show denticle belt fusions.

      (Yao et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      iHoge02142
      ihoge02142
      (Hartman et al., 2010)
      ihoge
      (Hartman et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)