FB2024_03 , released June 25, 2024
Allele: Dmel\ihogKG
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General Information
Symbol
Dmel\ihogKG
Species
D. melanogaster
Name
FlyBase ID
FBal0195789
Feature type
allele
Associated gene
Dmel\ihog
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Yao et al., 2006)
Progenitor genotype
P{SUPor-P}Fgop2KG05348
(Yao et al., 2006)
Caused by aberration
Df(2L)iHogKG
Cytology
Description

Imprecise excision of the P{SUPor-P} element, resulting in deletion from +1979 of the ihog coding sequence to the original P{SUPor-P} insertion site. This removes the sequence encoding the transmembrane domain of the ihog protein and some of the 5'UTR of the Fgop2 gene.

(Yao et al., 2006)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      iHogKG maternal germ-line clones produce embryos with denticle belt fusions. In contrast, zygotically homozygous iHoge02142 embryos exhibit no cuticle phenotype. Embryos from iHogKG maternal germ-line clones with paternally-provided iHoge02142 show less severe denticle belt fusions.

      Flies carrying iHogKG clones show a decrease in the extent of the intervein region between L3 and L4 in the wing.

      (Yao et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      ihogKG has ventral denticle belt | embryonic stage phenotype, enhanceable by dlpA187

      (Yao et al., 2006)
      NOT Suppressor of
      Statement
      Reference

      ihogKG/ihogKG is a non-suppressor of ventral denticle belt | embryonic stage phenotype of ptc9

      (Yao et al., 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      In contrast to zygotic iHogKG single mutants, iHogKG; dlpA187 zygotic double mutants show denticle belt fusions.

      Embryos with maternal/zygotic iHogKG and zygotic ptc9 show the denticle belt duplication phenotype of ptc9 single mutants and not the denticle belt fusion phenotype of iHogKG maternal/zygotic single mutants.

      (Yao et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      iHogKG
      (Yao et al., 2006)
      ihogKG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)