FB2024_03 , released June 25, 2024
Allele: Dmel\SdcUAS.cSa
Open Close
General Information
Symbol
Dmel\SdcUAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Steigemann
FlyBase ID
FBal0155818
Feature type
allele
Associated gene
Dmel\Sdc
Associated Insertion(s)
Carried in Construct
P{UAS-Sdc.S}
Key Links
Transgenic product class
cDNA
(Steigemann et al., 2004)
wild_type
(Steigemann et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Steigemann et al., 2004)
wild_type
(Steigemann et al., 2004)
Mutagen
in vitro construct
(Steigemann et al., 2004)
Progenitor genotype
Carried in construct
P{UAS-Sdc.S}
Cytology
Description

UASt regulatory sequences drive expression of the Sdc LD08230 EST.

(Steigemann et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Sdc
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of SdcScer\UAS.cSa under the control of Scer\GAL4elav-C155 has no effect on Fas2-expressing axons or commissures in the central nervous system and the myotube pattern is normal.

      (Steigemann et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      SdcUAS.cSa/Scer\GAL4da.G32 is a non-suppressor of eye photoreceptor cell & axon phenotype of dlp1/dlp2

      (Rawson et al., 2005)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of SdcScer\UAS.cSa, under the control of Scer\GAL4da.G32, fails to rescue the axon guidance defects of dlp1/dlp2 mutants.

      (Rawson et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4elav-C155/SdcUAS.cSa rescues Sdcunspecified

      (Steigemann et al., 2004)
      Partially rescues

      Scer\GAL4elav-C155/SdcUAS.cSa partially rescues Sdc48/Sdc10608

      (Rawson et al., 2005)
      Fails to rescue

      SdcUAS.cSa/Scer\GAL4sim.PS fails to rescue Sdcunspecified

      (Steigemann et al., 2004)
      Comments

      Expression of SdcScer\UAS.cSa, under the control of Scer\GAL4elav-C155, rescues the medulla cartridge crossover and R7/R8 termini disruption pupal phenotypes of Df(2R)48/Sdc10608 mutants (in which Sara function has been rescued by SaraUbi.PJ). However, this expression fails to rescue photoreceptor projection defects to the larval lamina or ERG abnormalities in adults.

      (Rawson et al., 2005)

      Expression of SdcScer\UAS.cSa under the control of Scer\GAL4elav-C155 rescues the Sdcunspecified phenotype of axons crossing the ventral midline. Expression of SdcScer\UAS.cSa under the control of Scer\GAL4sim.PS does not rescue the Sdcunspecified phenotype of axons crossing the ventral midline.

      (Steigemann et al., 2004)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      SdcScer\UAS.cSa
      SdcUAS.cSa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Steigemann
      (Steigemann et al., 2004)
      Secondary FlyBase IDs
        References (4)