Molecular lesion given with respect to transcript model Gfat1-RN.
Amino acid replacement: Y334term.
T4136552R
Y334term | Gfat1-PA; Y313term | Gfat1-PD; Y74term | Gfat1-PF; Y325term | Gfat1-PH; Y283term | Gfat1-PJ; Y133term | Gfat1-PK; Y322term | Gfat1-PL; Y305term | Gfat1-PM; Y334term | Gfat1-PN
Y334term
Amino acid change reported relative to Gfat1-PN. Site and nature of nucleotide substitution in mutant inferred by FlyBase curator based on reported amino acid change.
lethal (with Df(3R)7B-90)
lethal (with Gfat1I400-1)
lethal (with Gfat1I400-8)
lethal (with Gfat1Z1014)
lethal (with Gfat1Z1608)
Homozygous embryos often reverse themselves within the eggshell (26.6% of embryos show this "retroactive" phenotype). When the embryos are mechanically devitellinised the resulting cuticle preparations stretch to a much greater extent than wild-type cuticles, resulting in inflated cuticles ("blimp" phenotype). The head skeleton and denticle belts are almost wild type. Homozygous embryos are occasionally able to hatch.
Gfat1zep-LP13/zep[+], shg1 has embryonic/first instar larval cuticle phenotype
Gfat1zep-LP13, shg1 has embryonic/first instar larval cuticle phenotype
Gfat1zep-LP13/Df(3R)7B-90 is rescued by Scer\GAL4Act5C.PU/Gfat1UAS.cCa