FlyBase Allele Report: Dmel\Pdf[01]

General Information

Symbol

Dmel\Pdf⁰¹

Species

D. melanogaster

Name

FlyBase ID

FBal0102946

Feature type

allele

Associated gene

Dmel\Pdf

Associated Insertion(s)

Carried in Construct

Also Known As

pdf⁰

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Amino acid replacement: Y21term.

(Renn et al., 1999)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

3R:26,456,001..26,456,001 [-]

Nucleotide change:

C26456001R

Amino acid change:

Y21term | Pdf-PA

Reported amino acid change:

Y21term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Renn et al., 1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal behavior

(Yoshii et al., 2005)

abnormal behavior | recessive

(Toma et al., 2002)

abnormal circadian behavior

(Petsakou et al., 2015, Beckwith et al., 2011)

abnormal circadian behavior | adult stage

(King et al., 2017, Sheeba et al., 2010, Parisky et al., 2008)

abnormal circadian behavior | recessive

(Shafer and Taghert, 2009)

abnormal circadian rhythm

(Chung et al., 2009, Lin et al., 2004)

abnormal circadian rhythm | adult stage

(Herrero et al., 2020)

abnormal eclosion rhythm

(Selcho et al., 2017)

abnormal locomotor behavior | adult stage

(Mertens et al., 2005)

abnormal locomotor rhythm

(Duvall and Taghert, 2012, Im and Taghert, 2010, Bahn et al., 2009, Choi et al., 2009, Miyasako et al., 2007, Picot et al., 2007, Mertens et al., 2005, Klarsfeld et al., 2004, Peng et al., 2003)

abnormal locomotor rhythm | adult stage

(Niu et al., 2019, Seki and Tanimura, 2014)

abnormal locomotor rhythm | recessive

(Renn et al., 1999)

abnormal mating

(Krupp et al., 2013)

abnormal mating rhythm

(Krupp et al., 2013)

abnormal neuroanatomy | adult stage

(Herrero et al., 2020)

abnormal temperature response | adult stage

(Goda et al., 2016)

photoperiod response variant

(Klarsfeld et al., 2004)

Phenotype Manifest In

adult s-LNv neuron | adult stage

(Herrero et al., 2020)

LNd neuron

(Lin et al., 2004)

LNv neuron

(Lin et al., 2004)

Detailed Description

Statement

Reference

Pdf⁰¹ mutant adults have advanced evening peak circadian locomotor activity under light-dark (LD) conditions, compared to controls.

(Niu et al., 2019)

Pdf⁰¹ mutants show a relatively normal temperature preference during daytime, as compare to controls.

(Goda et al., 2018)

Pdf⁰¹ mutant adults have significantly reduced strength of circadian locomotor rhythms under constant darkness, compared to heterozygous controls.

(King et al., 2017)

Pdf[01] null mutants still display residual rhythmicity in emergence for the first two days after transfer to constant darkness, similar to controls; this is lost at later timepoints.

(Selcho et al., 2017)

Pdf⁰¹ homozygous mutant adults, reared under 12:12 light:dark zeitgeber cycle, present an advanced temperature preference rhythm phenotype and a significantly decreased night-time preferred temperature (zeitgeber times 16-24), but still display a similar day-time preferred temperature increase (between zeitgeber times 1-3 and 10-12) and a similar night-onset preferred temperature decrease (between zeitgeber times 10-12 and 13-15), as compared to controls.

(Goda et al., 2016)

Pdf⁰¹ mutants exhibit light-dependent temperature preference similar to that of wild-type.

(Head et al., 2015)

In contrast to controls, which adjust their morning and evening activity peaks to align with seasonal dawn and dusk, Pdf⁰¹ mutant flies show defective morning behavior when exposed to either a winter light:dark cycle (10 hours day:14 hours night) or a summer cycle (14 hours day:10 hours night).

(Petsakou et al., 2015)

Unlike wild-type, vast majority of Pdf⁰¹ mutant adults show a distinct ultradian rhythmicity in walking activity under constant dark conditions, with a mean ultradian period of about 50-60min. The period of this ultradian rhythmicity is highly temperature-dependent, with Q[10] coefficient of 2.68 for temperatures between 20-27.5oC.

(Seki and Tanimura, 2014)

Mutant males show a dramatic reduction in the amount of (z)-7-Tricosene, (z)-5-Tricosene and (z)-7-Pentacosene at all circadian time points and a loss of the subjective day/night difference compared to wild type (measured on the sixth day of constant darkness).

Pdf⁰¹ males mate more frequently than Canton-S males, regardless of the genotype of the females, but less often with Pdf⁰¹ females than with Canton-S females.

(Krupp et al., 2013)

Pdf⁰¹ mutants exhibit daytime temperature preference rhythms similar to those of wild-type flies during LD.

(Kaneko et al., 2012)

Pdf⁰¹ flies under LD conditions show no increased morning activity before lights-on, with evening anticipatory activity becoming advanced and reduced in amplitude. Furthermore, they show decreased rhythmicity and a shortened circadian period under DD.

(Beckwith et al., 2011)

Pdf⁰¹ mutants exhibit wild-type triglyceride levels.

(Diangelo et al., 2011)

Mutant flies lack the normal morning peak of circadian locomotor activity under 12 hour light:12 hour dark conditions.

(Im and Taghert, 2010)

Pdf⁰¹ mutant adult flies do not display any morning and evening anticipation behavior (and a corresponding peak in locomotor activity) when kept in constant darkness.

(Sheeba et al., 2010)

Approximately 67% of mutant flies show arrhythmic or weakly rhythmic locomotor activity under constant darkness conditions.

(Bahn et al., 2009)

Pdf⁰¹ flies exhibit severe deficits in free-running locomotor rhythms, with ~50% arrythmicity in flies in constant darkness.

(Choi et al., 2009)

Under light:dark (LD) conditions, mutant flies show increases in sleep during the late night. At the time when wild-type flies are waking up in advance of lights-on, the mutant flies fail to wake up.

During the first day of constant darkness (DD) conditions, mutant flies show a significant increase in total sleep during the subjective day compared to control flies.

(Chung et al., 2009)

Pdf⁰¹ mutants display reduced morning anticipation and an advanced evening peak under light/dark cycles, and high levels of arhythmicity and a shortened free-running period under constant darkness.

(Shafer and Taghert, 2009)

Compared to controls, Pdf⁰¹ mutant flies show significantly more daytime sleep in light/dark or dark/dark conditions. The increase in daytime sleep is primarily due to a decrease in wake duration/consolidation during the day. Sleep latency is decreased in the light period of light/dark experiments, and in the subjective night period of dark/dark experiments compared to controls.

(Parisky et al., 2008)

Pdf⁰¹ mutants under 12h:12h light:dark cycles show a significantly advanced evening activity peak, which becomes more pronounced if in combination with synchronous 25[o] C:20 [o]C (or 20[o] C:10 [o]C) temperature cycles, as compared to controls; when the temperature cycle is advanced by 6h, the evening activity peak occurs even earlier and the activity gradually decreases toward lights-off.

(Miyasako et al., 2007)

Under constant light conditions, about 55% of Pdf⁰¹ mutants display locomotor activity rhythms. Under the same conditions, only 10% of the wild-type controls show activity rhythms.

Under constant darkness, 50% of Pdf⁰¹ mutants display rhythms of locomotor activity with a period of about 22.5h.

(Picot et al., 2007)

Pdf⁰¹ mutant larvae show no significant differences from wild-type larvae in larval light avoidance assays. Pdf⁰¹ mutants, like wild-type larvae, display circadian modulation of photophobic behaviour.

(Mazzoni et al., 2005)

Pdf⁰¹ flies display an absence of lights-on anticipation and a phase advancement in the evening peak (lights-off anticipation).

Approximately 44% of homozygous Pdf⁰¹ mutants display rhythmic locomotion.

Approximately 83% of heterozygous Pdf⁰¹ mutants display rhythmic locomotion.

(Mertens et al., 2005)

Pdf⁰¹ homozygous flies display a strong negative geotaxis phenotype.

(Mertens et al., 2005)

Mutant flies are arrhythmic for locomotor activity under constant light conditions at a constant temperature of 25[o]C, but become rhythmic after being exposed to a temperature cycle of 12 hours at 25[o]C and 12 hours at 30[o]C. The flies show two clear peaks at temperature transitions and an anticipatory activity before the temperature step-down. However, the anticipatory activity is not so sharp but rather dispersed in comparison with that of the wild-type flies. Some transient cycles are observed until establishment of a stable phase-angle relationship with the temperature cycle.

(Yoshii et al., 2005)

Pdf⁰¹ flies kept in constant darkness show weak short-period rhythmicity.

(Klarsfeld et al., 2004)

Loss of locomotor behavior is observed in 70% of Pdf⁰¹ flies and manifests gradually with residual rhythms being present for 2-3 days after release into constant dark conditions. In the brains of these flies, the phasing of ventral LN neurons disperses over time and the dorsal LN neurons phase advance when kept in constant darkness compared to control flies.

(Lin et al., 2004)

Homozygous or hemizygous mutant animals exhibit a normal response to cocaine exposure.

(Tsai et al., 2004)

Pdf⁰¹ homozygous adults gradually lose circadian locomotor activity rhythms when kept in constant darkness. However, a significant fraction of are still weakly rhythmic after 4 days in constant darkness, but most of these accumulate an approximately 4-hour phase advance by this time relative to wild-type flies kept under the same conditions.

(Peng et al., 2003)

Varying the dosage of Pdf significantly affects geotaxic behaviour. Order of geotaxis scores (genetic background for all Pdf alleles = Canton-S): Hi5 strain > Pdf⁰¹/Pdf⁰¹ (males > females) > Pdf⁰¹/Pdf⁰¹; Pdf^+t3.530 (males > females) > Pdf⁰¹/Pdf⁰¹; Pdf^+t3.530/Pdf^+t3.530 (males > females) > Pdf⁰¹/+ = Canton-S > Pdf^+t3.530 => Pdf^+t3.530/Pdf^+t3.530 >> Lo strain.

(Toma et al., 2002)

Pdf⁰¹ flies display only two peaks of locomotor activity under cycling conditions. The morning peak lacks anticipation and is very narrow; the evening peak shows anticipation is sustained and is phase-advanced relative that of wild-type. Pdf⁰¹ flies remain rhythmic under constant conditions (DD) for days 1-2, but only 16% remain rhythmic over DD days 3-9.

(Taghert et al., 2001)

The number and morphology of LN_v neurons, and tritocerebral and abdominal neurons that normally express Pdf is normal in hemizygous Pdf⁰¹/Df(3R)Tl-X flies. The locomotor activity of hemizygous Pdf⁰¹ flies is not entirely normal. The flies are well entrained during 12 hour light:12 hour dark (LD) cycles, but the evening activity peak is advanced by approximately 1 hour compared to wild-type flies and there is a lack of lights-on anticipation. Free-running locomotor activity in constant darkness is severely abnormal. Homozygous and hemizygous flies are much less rhythmic than wild-type controls. 50-98% of mutant flies show no detectable rhythmicity for the duration of 9 days in constant darkness. Most flies are rhythmic for 2 or 3 days in constant darkness but later lose rhythmicity. Homozygous and hemizygous flies that do maintain rhythmicity have free-running periods approximately 1 hour shorter than wild-type or heterozygous flies.

(Renn et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Pdf⁰¹ has abnormal circadian rhythm phenotype, enhanceable by robo1^BG01092

(Berni et al., 2008)

NOT Enhanced by

Statement

Reference

Pdf⁰¹ has abnormal neuroanatomy | adult stage phenotype, non-enhanceable by TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a

(Herrero et al., 2020)

Pdf⁰¹ has abnormal circadian rhythm | adult stage phenotype, non-enhanceable by TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a

(Herrero et al., 2020)

Pdf⁰¹ has abnormal locomotor rhythm | adult stage phenotype, non-enhanceable by mir-210^KO

(Niu et al., 2019)

Pdf⁰¹ has abnormal locomotor rhythm phenotype, non-enhanceable by cry^b

(Picot et al., 2007)

Suppressed by

Statement

Reference

Dh31⁵¹, Pdf⁰¹ has abnormal temperature response | adult stage phenotype, suppressible | partially by Scer\GAL4^tim.UAS/Dh31^{UAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1)}

(Goda et al., 2018)

Pdf⁰¹ has abnormal circadian behavior phenotype, suppressible by Cprd\ΒPDH-I^UAS.cBa/Scer\GAL4^P2.4.Pdf

(Beckwith et al., 2011)

Pdf⁰¹ has abnormal locomotor rhythm phenotype, suppressible by Dvir\Pdf^+t3.5

(Bahn et al., 2009)

NOT suppressed by

Statement

Reference

Pdf⁰¹ has abnormal neuroanatomy | adult stage phenotype, non-suppressible by TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a

(Herrero et al., 2020)

Pdf⁰¹ has abnormal circadian rhythm | adult stage phenotype, non-suppressible by TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a

(Herrero et al., 2020)

Pdf⁰¹ has abnormal locomotor rhythm | adult stage phenotype, non-suppressible by mir-210^KO

(Niu et al., 2019)

Dh31⁵¹, Pdf⁰¹ has abnormal temperature response | adult stage phenotype, non-suppressible by Pdf^{UAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1)}/Scer\GAL4^tim.UAS

(Goda et al., 2018)

Dh31⁵¹, Pdf⁰¹ has abnormal temperature response | adult stage phenotype, non-suppressible by Pdf^{UAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1)}/Scer\GAL4^P2.4.Pdf

(Goda et al., 2018)

Dh31⁵¹, Pdf⁰¹ has abnormal temperature response | adult stage phenotype, non-suppressible by Pdf^{UAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1)}/Scer\GAL4^GMR18H11

(Goda et al., 2018)

Dh31⁵¹, Pdf⁰¹ has abnormal temperature response | adult stage phenotype, non-suppressible by Pdf^{UAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1)}/Scer\GAL4^Clk.int1-3/Scer\GAL80^Pdf.PS

(Goda et al., 2018)

Dh31⁵¹, Pdf⁰¹ has abnormal temperature response | adult stage phenotype, non-suppressible by Scer\GAL4^NP6301/Pdf^{UAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1)}

(Goda et al., 2018)

Dh31⁵¹, Pdf⁰¹ has abnormal temperature response | adult stage phenotype, non-suppressible by Dh31^{UAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1)}/Scer\GAL4^P2.4.Pdf

(Goda et al., 2018)

Dh31⁵¹, Pdf⁰¹ has abnormal temperature response | adult stage phenotype, non-suppressible by Scer\GAL4^GMR18H11/Dh31^{UAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1)}

(Goda et al., 2018)

Dh31⁵¹, Pdf⁰¹ has abnormal temperature response | adult stage phenotype, non-suppressible by Dh31^{UAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1)}/Scer\GAL4^Clk.int1-3/Scer\GAL80^Pdf.PS

(Goda et al., 2018)

Dh31⁵¹, Pdf⁰¹ has abnormal temperature response | adult stage phenotype, non-suppressible by Scer\GAL4^NP6301/Dh31^{UAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1)}

(Goda et al., 2018)

Pdf⁰¹ has photoperiod response variant phenotype, non-suppressible by gl^60j

(Klarsfeld et al., 2004)

Pdf⁰¹ has abnormal locomotor rhythm phenotype, non-suppressible by gl^60j

(Klarsfeld et al., 2004)

Pdf⁰¹ has photoperiod response variant phenotype, non-suppressible by hid^GMR.PG

(Klarsfeld et al., 2004)

Pdf⁰¹ has abnormal locomotor rhythm phenotype, non-suppressible by hid^GMR.PG

(Klarsfeld et al., 2004)

NOT Enhancer of

Statement

Reference

Pdf⁰¹ is a non-enhancer of abnormal locomotor rhythm | adult stage phenotype of mir-210^KO

(Niu et al., 2019)

Pdf⁰¹ is a non-enhancer of abnormal locomotor rhythm phenotype of cry^b

(Picot et al., 2007)

Pdf⁰¹ is a non-enhancer of abnormal circadian rhythm phenotype of Clk^UAS.cZa, Scer\GAL4^cry.PZ

(Zhao et al., 2003)

Suppressor of

Statement

Reference

Pdf⁰¹ is a suppressor of abnormal sleep phenotype of wake^D2

(Liu et al., 2014)

NOT Suppressor of

Statement

Reference

Pdf⁰¹ is a non-suppressor of abnormal locomotor rhythm | adult stage phenotype of mir-210^KO

(Niu et al., 2019)

Pdf⁰¹ is a non-suppressor of abnormal circadian rhythm phenotype of Clk^UAS.cZa, Scer\GAL4^cry.PZ

(Zhao et al., 2003)

Other

Statement

Reference

Dh31⁵¹, Pdf⁰¹ has abnormal temperature response | adult stage phenotype

(Goda et al., 2018)

Pdf⁰¹/Pdf[+], Pdfr^EY11851 has abnormal locomotor behavior | adult stage phenotype

(Mertens et al., 2005)

Pdf⁰¹/Pdf[+], Pdfr^P2-36 has abnormal locomotor behavior | adult stage phenotype

(Mertens et al., 2005)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Pdf⁰¹ has adult s-LNv neuron | adult stage phenotype, non-enhanceable by TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a

(Herrero et al., 2020)

NOT suppressed by

Statement

Reference

Pdf⁰¹ has adult s-LNv neuron | adult stage phenotype, non-suppressible by TrpA1^UAS.(B).cKa/Scer\GAL4^Pdf.Switch1a

(Herrero et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Dh31⁵¹, Pdf⁰¹ double mutants show a relatively high and constant temperature preference (~26[o]C) during daytime in 12h:12h light:dark cycles, and show a relatively low and constant temperature (~24[o]C) under constant darkness conditions, as compared o controls.

(Goda et al., 2018)

Dh31⁵¹; Pdf⁰¹ double mutants exhibit light-dependent temperature preference similar to that of wild-type.

(Head et al., 2015)

The increase in sleep latency seen in wake^D2 flies is blocked if they are also mutant for Pdf⁰¹.

(Liu et al., 2014)

robo^BG01092 Pdf⁰¹ double mutants exhibit a lengthening of the free-running period in a dose-dependent manner. Introducing a copy of robo^BG01092 into Pdf⁰¹ mutants gives rise to >80% rhythmic individuals. The average activity plot of robo^BG01092 Pdf⁰¹ flies shows a modest increase in the activity ~1hr before the lights-on transition, indicating that the morning anticipation is rescued even in the absence of Pdf neuropeptide.

robo^BG01092 Pdf⁰¹ double mutants show a significantly lengthened period of locomotor activity.

Transheterozygous robo^BG01092 Pdf⁰¹ flies display wild-type period and rhythmicity.

(Berni et al., 2008)

Under constant light, cry^b Pdf⁰¹ double mutants display locomotor rhythms that are similar to cry^b mutants. Conversely, cry^b Pdf⁰¹ double mutants display locomotor rhythms that are similar to Pdf⁰¹ single mutants under constant darkness.

(Picot et al., 2007)

pdfr^P2-36 in trans with Pdf⁰¹ displays severe negative geotaxis.

(Mertens et al., 2005)

gl^60j, Pdf⁰¹ and W^GMR.PG; Pdf⁰¹ flies show similar weak short-period rhythmicity phenotypes when kept in constant darkness to Pdf⁰¹ single mutant flies.

(Klarsfeld et al., 2004)

Xenogenetic Interactions

Statement

Reference

Expression of Zzzz\ΒPDH-I^Scer\UAS.cBa in the PDF circuit, under the control of Scer\GAL4^P2.4.Pdf, suppresses the homozygous Pdf⁰¹ mutant circadian behavior phenotype. In contrast, expression of Zzzz\ΒPDH-II^Scer\UAS.cBa in the PDF circuit under the control of Scer\GAL4^P2.4.Pdf, in a homozygous Pdf⁰¹ mutant background, only modestly improves the rhythmicity, with the flies displaying a unconsolidated activity profile. In addition, these flies show a short circadian period, reminiscent of Pdf⁰¹ mutant flies.

Expression of Zzzz\ΒPDH-II^Scer\UAS.cBa in the PDF circuit under the control of Scer\GAL4^P2.4.Pdf fails to suppress the modest morning peak and an evening peak of activity that's found in Pdf⁰¹ mutants.

(Beckwith et al., 2011)

The defects in locomotor activity rhythms seen in D. melanogaster Pdf⁰¹ flies under constant darkness conditions are completely rescued if the flies are also carrying Dvir\Pdf^+t3.5.

(Bahn et al., 2009)

Complementation and Rescue Data

Rescued by

Pdf⁰¹ is rescued by Pdf^UAS.cRa/Scer\GAL4^P2.4.Pdf

(Beckwith et al., 2011)

Partially rescued by

Pdf⁰¹ is partially rescued by Pdf^+t3.530

(Krupp et al., 2013)

Pdf⁰¹ is partially rescued by Pdf^{UAS.ML.Tag:SS(trypsin).Tag:MYC.Tag:GPI(lynx1)}/Scer\GAL4^tim.UAS

(Choi et al., 2009)

Pdf⁰¹ is partially rescued by Pdf^UAS.cRa/Scer\GAL4^P2.4.Pdf

(Renn et al., 1999)

Pdf⁰¹ is partially rescued by Pdf^+t3.530

(Renn et al., 1999)

Comments

Pdf^+t3.530 partially rescues the sex pheromone expression profile of Pdf⁰¹ males: (z)-5-Tricosene and (z)-7-Pentacosene are rescued to near wild-type levels, but (z)-7-Tricosene expression and the subjective day/night differences are not rescued (measured on the sixth day of constant darkness).

(Krupp et al., 2013)

Expression of Pdf^Scer\UAS.cRa under the control of Scer\GAL4^P2.4.Pdf rescues the Pdf⁰¹ circadian behavior phenotype.

(Beckwith et al., 2011)

Pdf⁰¹ flies that also express Pdf^{Scer\UAS.ML.T:SS-trypsin.T:Hsap\MYC.T:GPI-lynx1} under the control of Scer\GAL4^tim.Scer\UAS exhibit little arrhythmicity in constant darkness (unlike Pdf⁰¹ only flies), with only ~10% of flies arrhythmic and most exhibiting instead a complex free-running rhythm (which is still abnormal compared to wild type).

(Choi et al., 2009)

Pdf^+t3.530 or Pdf^Scer\UAS.cRa expressed under the control of Scer\GAL4^P2.4.Pdf partially rescues the locomotor activity defects of Pdf⁰¹ flies.

(Renn et al., 1999)

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

26654

y¹ w^*; Pdf⁰¹

80985

w^*; P{GawB}Kurs58/CyO; Pdf⁰¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Pdf⁰

(Górska-Andrzejak et al., 2018, Dissel et al., 2014)

pdf⁰

(Johard et al., 2009, Yoshii et al., 2008, Picot et al., 2007, Williams et al., 2001)

Name Synonyms

Secondary FlyBase IDs

References (69)

Report Sections

Open Close