FlyBase Allele Report: Dmel\mbl[E127]

General Information

Symbol

Dmel\mbl^E127

Species

D. melanogaster

Name

FlyBase ID

FBal0082452

Feature type

allele

Associated gene

Dmel\mbl

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Begemann et al., 1997)

Progenitor genotype

mbl^k05507b

(Begemann et al., 1997)

Cytology

Description

Imprecise excision removing exon 1, deletion does not extend into the coding region.

(Begemann et al., 1997)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal courtship behavior | female (with mbl^chst)

(Juni and Yamamoto, 2009)

lethal (with mbl^chst-exC3)

(Juni and Yamamoto, 2009)

lethal (with mbl^chst-exC45)

(Juni and Yamamoto, 2009)

lethal (with mbl^chst-exC110)

(Juni and Yamamoto, 2009)

lethal (with mbl^chst-exS31)

(Juni and Yamamoto, 2009)

lethal (with mbl^E27)

(Juni and Yamamoto, 2009)

lethal (with mbl^k05507b)

(Juni and Yamamoto, 2009)

lethal | recessive

(Begemann et al., 1997)

partially lethal - majority die (with mbl^k07110)

(Juni and Yamamoto, 2009)

viable (with mbl^chst)

(Juni and Yamamoto, 2009)

viable (with mbl^E2563-12)

(Juni and Yamamoto, 2009)

viable (with mbl^k07103)

(Juni and Yamamoto, 2009)

Phenotype Manifest In

rhabdomere R2

(Begemann et al., 1997)

rhabdomere R3

(Begemann et al., 1997)

rhabdomere R4

(Begemann et al., 1997)

rhabdomere R5

(Begemann et al., 1997)

Detailed Description

Statement

Reference

mbl^chst/mbl^E127 females show reduced sexual receptivity compared to controls.

(Juni and Yamamoto, 2009)

Mutant clones in the eye exhibit phenotypic defects in many mutant ommatidia, the rhabdomeres of up to 4 outer photoreceptors have a smaller diameter resembling the rhabdomeres of receptor cell R7. All photoreceptors could be affected with malformed rhabdomeres that frequently do not extend into basal regions of the retina.

(Begemann et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

mbl^E127 is a suppressor of phenotype of Jra^Asp.hs.sev

(Begemann et al., 1997)