FlyBase Allele Report: Dmel\mbl[chst]

General Information

Symbol

Dmel\mbl^chst

Species

D. melanogaster

Name

chaste

FlyBase ID

FBal0190023

Feature type

allele

Associated gene

Dmel\mbl

Associated Insertion(s)

P{BmΔ-w}mbl^chst

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{BmΔ-w}mbl^chst

Cytology

Description

Insertion approximately 400bp upstream of mbl.

(Juni and Yamamoto, 2009)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

AB036794

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal courtship behavior | female (with mbl^chst-exC3)

(Juni and Yamamoto, 2009)

abnormal courtship behavior | female (with mbl^chst-exC18)

(Juni and Yamamoto, 2009)

abnormal courtship behavior | female (with mbl^chst-exC24)

(Juni and Yamamoto, 2009)

abnormal courtship behavior | female (with mbl^chst-exC45)

(Juni and Yamamoto, 2009)

abnormal courtship behavior | female (with mbl^chst-exC67)

(Juni and Yamamoto, 2009)

abnormal courtship behavior | female (with mbl^chst-exC71)

(Juni and Yamamoto, 2009)

abnormal courtship behavior | female (with mbl^chst-exC106)

(Juni and Yamamoto, 2009)

abnormal courtship behavior | female (with mbl^chst-exC110)

(Juni and Yamamoto, 2009)

abnormal courtship behavior | female (with mbl^E27)

(Juni and Yamamoto, 2009)

abnormal courtship behavior | female (with mbl^E127)

(Juni and Yamamoto, 2009)

abnormal courtship behavior | female (with mbl^k05507b)

(Juni and Yamamoto, 2009)

abnormal courtship behavior | female (with mbl^k07103)

(Juni and Yamamoto, 2009)

abnormal courtship behavior | female (with mbl^k07110)

(Juni and Yamamoto, 2009)

abnormal courtship behavior | female | recessive

(Juni and Yamamoto, 2009)

partially lethal - majority die (with mbl^E27)

(Juni and Yamamoto, 2009)

viable

(Juni and Yamamoto, 2009)

viable (with mbl^chst-exC3)

(Juni and Yamamoto, 2009)

viable (with mbl^E127)

(Juni and Yamamoto, 2009)

viable (with mbl^E2563-12)

(Juni and Yamamoto, 2009)

viable (with mbl^k05507b)

(Juni and Yamamoto, 2009)

viable (with mbl^k07103)

(Juni and Yamamoto, 2009)

viable (with mbl^k07110)

(Juni and Yamamoto, 2009)

Phenotype Manifest In

Detailed Description

Statement

Reference

Mutant females show reduced mating success compared to control females. The level of courtship activity elicited in wild-type males by mutant females is comparable to that elicited by control females. The mutant females are approached by males, who attempt to copulate, but in most cases, without success. The mutant females show different behaviour in response to courting males compared to control females; although decamping is the most prevalent response pattern of the females in boht cases, the mutant females show flying and jumping significantly more often that wild-type females, in addition to decamping.

mbl^chst in transheterozygous combination with mbl^chst-exC18, mbl^chst-exC67, mbl^chst-exC106, mbl^chst-exC71, mbl^chst-exC3, mbl^chst-exC24, mbl^chst-exC110, mbl^chst-exC45, mbl^k05507b, mbl^E27, mbl^E127, mbl^k07110 or mbl^k07103 shows reduced female sexual receptivity compared to controls.