FB2024_03 , released June 25, 2024
Allele: Dmel\Pka-C1Cos-3R+E6
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General Information
Symbol
Dmel\Pka-C1Cos-3R+E6
Species
D. melanogaster
Name
FlyBase ID
FBal0063546
Feature type
allele
Associated gene
Dmel\Pka-C1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Grau and Simpson, 1987)
Progenitor genotype
Pka-C1Cos-3
(Grau and Simpson, 1987)
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Viable when transheterozygous with "Cos" neomorphic alleles, and viable and phenotypically wild type when transheterozygous with "Cos" revertants.

      (Grau and Simpson, 1987)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Revertant. Associated with: Unmapped recessive lethal mutation. Selected as: Lack of wing phenotype.

      (Grau and Simpson, 1987)
      Comments
      Comments

      FBrf0179171 demonstrates that a number of alleles previously assigned to the "Cos" locus actually map to two separate genes; Pka-C1 and Pka-R2. This allele, previously referred to in FlyBase as "Cos3R+E6", has been assigned to the Pka-C1 locus because it is a revertant of the Pka-C1Cos-3 allele, which was demonstrated in FBrf0179171 to be an allele of Pka-C1.

      (FlyBase, 1992-)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Cos-13R+E6
      (Grau and Simpson, 1987)
      Cos3R+E6
      Pka-C1Cos-3R+E6
      Name Synonyms
      Secondary FlyBase IDs
        References (2)