FlyBase Allele Report: Dmel\sax[1rv5]

General Information

Symbol

Dmel\sax^1rv5

Species

D. melanogaster

Name

FlyBase ID

FBal0044328

Feature type

allele

Associated gene

Dmel\sax

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Twombly et al., 1996)

Progenitor genotype

sax¹

(Letsou et al., 1995)

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with Df(2R)H23)

(Twombly et al., 2009)

lethal (with Df(2R)sax-H9)

(Twombly et al., 2009)

lethal (with sax³)

(Twombly et al., 2009)

lethal (with sax⁴)

(Twombly et al., 2009)

lethal (with sax⁵)

(Twombly et al., 2009)

lethal (with sax⁶)

(Twombly et al., 2009)

lethal (with sax^P)

(Twombly et al., 2009)

viable (with sax¹)

(Twombly et al., 2009)

viable (with sax²)

(Twombly et al., 2009)

Phenotype Manifest In

egg chamber

(Twombly et al., 1996)

ovariole

(Twombly et al., 1996)

Detailed Description

Statement

Reference

sax³ exhibits a very low level of viability in trans to sax^1rv5.

(Twombly et al., 2009)

In hemizygous females rescued by sax^hs.PB but kept at 18^oC, 58% of mutant ovarioles show no chambers older than stage 9. Degenerating chambers are immediately posterior to abnormal stage 9 chambers.

(Twombly et al., 1996)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

When dpp[hr4]/+ males are crossed to sax^1rv5/+ females, the resulting dpp^hr4/+ progeny do not show any significant drop in viability compared to the dpp^hr4/+ progeny of wild-type mothers in control crosses.

(Twombly et al., 2009)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

sax^1rv5/Df(2R)sax-H9 is rescued by sax^hs.PB

(Twombly et al., 2009)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

M. Gelbart.

(Twombly et al., 1996)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

sax^1rv5

(Twombly et al., 2009)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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