FB2024_03 , released June 25, 2024
Allele: Dmel\SamsM6
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General Information
Symbol
Dmel\SamsM6
Species
D. melanogaster
Name
FlyBase ID
FBal0042661
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
l(2)M6
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Homozygotes die during the late embryonic and first larval instar stages. Females containing homozygous germline clones are fertile. 43% of the female progeny of homozygous female germline clones have a Minute-like bristle phenotype; bristles are short and often thinner than normal and scutellar bristles are occasionally absent. One side of the scutellum and thorax is often more affected than the other. 41% of these females have fused tergites. 25% of the male progeny of homozygous female germline clones have a Minute-like bristle phenotype, of which 23% also have fused tergites. 11% of the male progeny of homozygous female germline clones have rotated genitalia, which protrude from the body. In extreme cases, 180o rotation is seen.

    Dominant suppressor of z1 wis mutant phenotype.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Enhancer of
    Statement
    Reference

    SamsM6 is an enhancer of phenotype of Pc11

    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    Comments
    Comments

    Somatic clonal analysis indicates that M(2)21AB is required for cell proliferation or growth during development of the eye imaginal disc.

    Mutant has lost the developmental delay, the Minute characteristics and the female temperature sensitive sterility previously described in FBrf0028903.

    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (4)
    Reported As
    Name Synonyms
    Secondary FlyBase IDs
      References (4)