Two amino acid deletion at amino acids 69 and 70 within the chromo domain.
Pc11 is a two amino acid deletion at amino acids 69 and 70 within the chromo domain.
Pc11 heterozygous males show a highly prevalent ectopic sex comb phenotype.
Heterozygous males have an extra sex comb phenotype that is more pronounced at 29[o]C than at 25[o]C.
Pc11/+ suppresses the telomeric position effect (TPE) of P{hsp26-pt-T}39C-5, P{hsp26-pt-T}39C-27, P{hsp26-pt-T}39C-31 and P{wA}4-4.
Heterozygotes show transformation of second and third legs to first leg, resulting in extra sex combs. Most heterozygotes have normal wings and very few show a mild transformation of the wing to haltere.
Partial transformations of second and third legs into first legs in Pc/+ heterozygotes.
Very strong haploinsufficient Pc phenotype.
Pc11 has visible | male phenotype, enhanceable by CCT7KG01477
Pc11 has visible | male phenotype, enhanceable by CCT7KG09501
Pc11 has visible | male phenotype, enhanceable by CCT5k06005
Pc11 has visible | dominant | homeotic phenotype, enhanceable by Dsp1UAS.cDa/Scer\GAL4hs.PB
Pc11 has homeotic | adult stage phenotype, suppressible by enok[+]/enok2
Pc11 has homeotic | adult stage phenotype, suppressible by enok1/enok[+]
Pc11 has sex comb phenotype, enhanceable by CCT7KG01477
Pc11 has sex comb phenotype, enhanceable by CCT7KG09501
Pc11 has sex comb phenotype, enhanceable by CCT5k06005
Pc11 has haltere | ectopic phenotype, enhanceable by Dsp1UAS.cDa/Scer\GAL4hs.PB
Pc11 has metathoracic leg phenotype, enhanceable by Dsp1UAS.cDa/Scer\GAL4hs.PB
Pc11 has sex comb | ectopic phenotype, enhanceable by Dsp1UAS.cDa/Scer\GAL4hs.PB
Pc11 has wing phenotype, enhanceable by Dsp1UAS.cDa/Scer\GAL4hs.PB
Pc11 has mesothoracic leg phenotype, suppressible by Dsp11
Pc11 has metathoracic leg phenotype, suppressible by Dsp11
rept06945 Pc11 double heterozygous males have ectopic sex combs on the second and third legs (47% and 5% of flies respectively).
MRG15j6A3 Pc11 double heterozygous males have ectopic sex combs on the second and third legs (85% and 54% of flies respectively).
MRG15ex1 shows no interaction (in terms of ectopic sex comb phenotype) when in double heterozygous combination with Pc11.
Approximately 100% of AntpD43/Pc11 animals show transformation of antenna into leg. The number of T2 and T3 legs with sex combs is reduced in Dsp11/Y ; Pc11/+ flies compared to Pc11/+ single mutants. The size of the sex comb on the first leg is almost normal in Dsp11/Y ; Pc11/+ flies. The majority of Pc11/+ heterozygotes in which Dsp1Scer\UAS.cDa is expressed under the control of Scer\GAL4hs.PB show a mild transformation of the wing to haltere and there is a considerable increase in the number of T3 legs with a sex comb.
Pc11 is rescued by PcTag:CS(TEVp),Tag:StrepII