FlyBase Allele Report: Dmel\Snr1[01319]

General Information

Symbol

Dmel\Snr1⁰¹³¹⁹

Species

D. melanogaster

Name

FlyBase ID

FBal0009408

Feature type

allele

Associated gene

Dmel\Snr1

Associated Insertion(s)

P{PZ}Snr1⁰¹³¹⁹

Carried in Construct

Also Known As

Snr1^P1

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Dingwall et al., 1995, BDGP Project Members, 1994-1999)

Progenitor genotype

Associated Insertion(s)

P{PZ}Snr1⁰¹³¹⁹

Cytology

Description

P{PZ} insertion within an exon of Snr1.

(Dingwall et al., 1995)

Allele components

Component

Use(s)

Inserted element

P{PZ}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:5,471,953..5,471,953 [+]

(Zhu et al., 2008, Zraly et al., 2003, Brumby et al., 2002, Spradling et al., 1999, Dingwall et al., 1995, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell shape | recessive

(Tea and Luo, 2011)

abnormal neuroanatomy | recessive

(Tea and Luo, 2011)

lethal | recessive

(Spradling et al., 1999)

lethal - all die before end of larval stage | recessive

(Dingwall et al., 1995)

lethal - all die during embryonic stage

(Jeibmann et al., 2014)

some die during larval stage | recessive

(Dingwall et al., 1995)

Phenotype Manifest In

adult antennal lobe projection neuron DL1 adPN

(Tea and Luo, 2011)

Detailed Description

Statement

Reference

PBac{GH146-GAL4.B}-marked anterodorsal single cell clones in Snr1⁰¹³¹⁹ mutants display mistargeting to non-stereotyped glomeruli throughout the antennal lobe. PBac{GH146-GAL4.B}-marked neuroblast clones in Snr1⁰¹³¹⁹ mutants display phenotypes where dendrites make small, meandering projections throughout the antennal lobe and exhibit extremely perturbed cell morphology.

(Tea and Luo, 2011)

brm² shows little if any interaction in double heterozygous combination with Snr1⁰¹³¹⁹; less than 3% of flies have held-out wings.

(Vazquez et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Snr1⁰¹³¹⁹/Snr1[+] is a non-enhancer of visible phenotype of ct^K

(Krupp et al., 2005)

Snr1⁰¹³¹⁹/Snr1[+] is a non-enhancer of visible phenotype of ct^53d

(Krupp et al., 2005)

Suppressor of

Statement

Reference

Snr1⁰¹³¹⁹/Snr1[+] is a suppressor of visible | adult stage phenotype of Marcal1^UAS.cBa, Scer\GAL4^Tub.PU

(Morimoto et al., 2016)

Snr1⁰¹³¹⁹/Snr1[+] is a suppressor of visible | adult stage phenotype of Hsap\SMARCAL1^UAS.cBa, Scer\GAL4^Bx-MS1096

(Morimoto et al., 2016)

Snr1⁰¹³¹⁹ is a suppressor of visible phenotype of Myc^UAS.cZa, Scer\GAL4^GMR.PF

(Secombe et al., 2007)

NOT Suppressor of

Statement

Reference

Snr1⁰¹³¹⁹/Snr1[+] is a non-suppressor of visible phenotype of ct^53d

(Krupp et al., 2005)

Snr1⁰¹³¹⁹/Snr1[+] is a non-suppressor of visible phenotype of ct^K

(Krupp et al., 2005)

Phenotype Manifest In

Enhancer of

Statement

Reference

Snr1⁰¹³¹⁹ is an enhancer of eye phenotype of Scer\GAL4^ey.PH, osa^UAS.cCa

(Collins et al., 1999)

NOT Enhancer of

Statement

Reference

Snr1⁰¹³¹⁹/Snr1[+] is a non-enhancer of leg phenotype of e(y)3⁴

(Chalkley et al., 2008)

Snr1⁰¹³¹⁹/Snr1[+] is a non-enhancer of triple row of wing sensilla phenotype of ct^K

(Krupp et al., 2005)

Snr1⁰¹³¹⁹/Snr1[+] is a non-enhancer of wing phenotype of ct^53d

(Krupp et al., 2005)

Suppressor of

Statement

Reference

Snr1⁰¹³¹⁹/Snr1[+] is a suppressor of wing vein | adult stage phenotype of Marcal1^UAS.cBa, Scer\GAL4^Tub.PU

(Morimoto et al., 2016)

Snr1⁰¹³¹⁹/Snr1[+] is a suppressor of wing vein | adult stage phenotype of Hsap\SMARCAL1^UAS.cBa, Scer\GAL4^Bx-MS1096

(Morimoto et al., 2016)

Snr1⁰¹³¹⁹ is a suppressor of eye phenotype of Myc^UAS.cZa, Scer\GAL4^GMR.PF

(Secombe et al., 2007)

Snr1⁰¹³¹⁹ is a suppressor of eye phenotype of CycE^JP

(Brumby et al., 2002)

NOT Suppressor of

Statement

Reference

Snr1⁰¹³¹⁹/Snr1[+] is a non-suppressor of wing phenotype of ct^53d

(Krupp et al., 2005)

Snr1⁰¹³¹⁹/Snr1[+] is a non-suppressor of triple row of wing sensilla phenotype of ct^K

(Krupp et al., 2005)

Other

Statement

Reference

Snr1⁰¹³¹⁹/Snr1[+], akirin^KG01343 has embryonic/larval somatic muscle cell phenotype

(Nowak et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

The formation of ectopic wing veins observed in adult flies expressing Marcal1^Scer\UAS.cBa under the control of Scer\GAL4^tub.PU is ameliorated by combination with a single copy of Snr1⁰¹³¹⁹.

(Morimoto et al., 2016)

Stage 16 Snr1⁰¹³¹⁹/+ ; akirin^KG01343/+ double heterozygous embryos show disruption of the somatic muscle pattern (45% of embryos have missing, misattached or duplicated muscles in at least 2 hemisegments).

(Nowak et al., 2012)

Suppresses the CycE^JP rough eye phenotype.

(Brumby et al., 2002)

The addition of Snr1⁰¹³¹⁹ enhances the eye size phenotype seen in osa^Scer\UAS.cCa/Scer\GAL4^ey.PH flies.

(Collins et al., 1999)

Xenogenetic Interactions

Statement

Reference

The formation of ectopic wing veins observed in adult flies expressing Hsap\SMARCAL1^Scer\UAS.cBa under the control of Scer\GAL4^Bx-MS1096 is ameliorated by combination with a single copy of Snr1⁰¹³¹⁹.

(Morimoto et al., 2016)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Complements: l(3)03644⁰³⁶⁴⁴. Complements: Itp-r83A⁰⁵⁶¹⁶. Complements: l(3)09904c^09904c. Complements: stumps^09904b. Complements: Itp-r83A^L2262b. Complements: Itp-r83A^j5B4. Complements: ksr^j5E2.

(BDGP Project Members, 1994-1999)

Mobilisation of the P{PZ} insertion demonstrates the insertion is responsible for the lethal phenotype.

(Dingwall et al., 1995)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (8)

Reported As

Symbol Synonym

Snr1⁰¹³¹⁹

(Nowak et al., 2012, Di Stefano et al., 2011, Tea and Luo, 2011)

Snr1^F1

(Collins et al., 1999)

Snr1^P1

(Zraly et al., 2003, Collins et al., 1999)

l(3)01319

(Spradling et al., 1999)

snr1⁰¹³¹⁹

(Jeibmann et al., 2014, Chalkley et al., 2008, Secombe et al., 2007)

snr1^P1

(Dingwall et al., 1995)

snr¹⁰¹³¹⁹

(Hong and Choi, 2016)

snr^P1

(Vazquez et al., 1999)

Name Synonyms

Secondary FlyBase IDs

References (18)

Report Sections

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