FB2024_03 , released June 25, 2024
Allele: Dmel\akirinKG01343
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General Information
Symbol
Dmel\akirinKG01343
Species
D. melanogaster
Name
FlyBase ID
FBal0137585
Feature type
allele
Associated gene
Dmel\akirin
Associated Insertion(s)
P{SUPor-P}akirinKG01343
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{SUPor-P}akirinKG01343
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous embryos show defects in the somatic musculature. 67.9% of embryos have missing muscles, 83% have muscle attachment defects and 18.9% have duplicated muscles. 46.5% of embryos have muscle defects in at least 2 hemisegments.

      akirinKG01343/akirinEP906 embryos show defects in the somatic musculature. 71.4% of embryos have missing muscles, 68.5% have muscle attachment defects and 25.7% have duplicated muscles. 67% of embryos have muscle defects in at least 2 hemisegments.

      (Nowak et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      akirinKG01343/+ results in disruption of the somatic muscle pattern when in double heterozygous combination with one of the following (% of stage 16 embryos with missing, misattached or duplicated muscles in at least 2 hemisegments is given in parentheses): twi1 (21.6%), brmI21 (35%), osa308 (42%), polybromoΔ86 (38%), mor1 (40%) or Snr101319 (45%).

      (Nowak et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      CG8580KG01343
      akirin2
      (Nowak et al., 2012)
      akirinKG01343
      (Nowak et al., 2012)
      bhrKG01343
      Name Synonyms
      Secondary FlyBase IDs
        References (2)