FB2024_03 , released June 25, 2024
Allele: Dmel\Abd-Biab9-48
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General Information
Symbol
Dmel\Abd-Biab9-48
Species
D. melanogaster
Name
FlyBase ID
FBal0000137
Feature type
allele
Associated gene
Dmel\Abd-B
Associated Insertion(s)
Carried in Construct
Also Known As
48, Abd-B.48
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Celniker et al., 1990)
Mutagen
X ray
(Kuhn et al., 1993)
Progenitor genotype
Caused by aberration
In(3R)Abd-Biab9-48
Cytology
Description

Breakpoint maps to between coordinates +159 and +165kb.

(Kuhn et al., 1993)

Lesion maps to between coordinates 160kb and 165kb of Karch et al. (FBrf0042053).

(Karch et al., 1990)

Lesion mapped to: +163-166.5 kb.

(Karch et al., 1985)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Third instar larvae have a large naked cuticle region posterior to the 8th denticle band and a rather complete 9th denticle band. Embryos lack posterior spiracles.

      (Kuhn et al., 1995)

      Homozygous males and homozygous females have eight abdominal segments. Suppresses penetrance of head defect phenotype when in trans with Abd-Biab9-tuh-3. Heterozygotes with Abd-Biab9-tuh-3 exhibit genital defects with relatively high penetrance. Abd-Biab9-tuh-3. Heterozygotes with Abd-Biab9-tuh-3 exhibit genital defects with relatively high penetrance.

      (Kuhn et al., 1993)

      A5-A8 (including female genitalia) transformed to A4 in mosaics. Embryos have extra denticles in A9, and parasegments 10-13 are transformed to parasegment 9.

      (Sanchez-Herrero and Crosby, 1988)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Abd-BUab-1

      (Sanchez-Herrero and Crosby, 1988)

      Abd-Biab9-x23-1

      (Sanchez-Herrero and Crosby, 1988)

      Abd-Biab9-tuh-3

      (Sanchez-Herrero and Crosby, 1988)

      Abd-Biab9-Tab

      (Sanchez-Herrero and Crosby, 1988)

      Abd-Biab8-D15

      (Sanchez-Herrero and Crosby, 1988)

      Abd-Biab8-D14

      (Sanchez-Herrero and Crosby, 1988)

      Abd-Biab8-D6

      (Sanchez-Herrero and Crosby, 1988)

      Abd-Biab8-rv82

      (Sanchez-Herrero and Crosby, 1988)

      Abd-Biab8-rv96

      (Sanchez-Herrero and Crosby, 1988)

      Abd-Biab8-rv111

      (Sanchez-Herrero and Crosby, 1988)

      Abd-Biab8-rv185

      (Sanchez-Herrero and Crosby, 1988)

      Abd-Biab8-rv100

      (Sanchez-Herrero and Crosby, 1988)

      Abd-Biab8-rv114

      (Sanchez-Herrero and Crosby, 1988)

      Abd-Biab8-rv89

      (Sanchez-Herrero and Crosby, 1988)

      Abd-Biab8-rv175

      (Sanchez-Herrero and Crosby, 1988)

      Abd-Biab8-rv107

      (Sanchez-Herrero and Crosby, 1988)

      Abd-BM9

      (Sanchez-Herrero and Crosby, 1988)

      Abd-BM7

      (Sanchez-Herrero and Crosby, 1988)

      Abd-BM4

      (Sanchez-Herrero and Crosby, 1988)

      Abd-BM2

      (Sanchez-Herrero and Crosby, 1988)

      Abd-B380

      (Sanchez-Herrero and Crosby, 1988)

      Abd-BS2

      (Sanchez-Herrero and Crosby, 1988)

      Abd-BS1

      (Sanchez-Herrero and Crosby, 1988)

      Abd-BM6

      (Sanchez-Herrero and Crosby, 1988)

      Abd-BM5

      (Sanchez-Herrero and Crosby, 1988)

      Abd-BM3

      (Sanchez-Herrero and Crosby, 1988)

      Abd-BS9

      (Sanchez-Herrero and Crosby, 1988)

      Abd-BS8

      (Sanchez-Herrero and Crosby, 1988)

      Abd-BS5

      (Sanchez-Herrero and Crosby, 1988)

      Abd-BR

      (Sanchez-Herrero and Crosby, 1988)

      Abd-BF

      (Sanchez-Herrero and Crosby, 1988)
      Comments

      Fails to complement all mutations in the Abd-B domain. Interactions with Abd-B domain mutations may be variable & weak.

      (Sanchez-Herrero and Crosby, 1988)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      R.H. Baker.

      Comments
      Comments

      Less extreme than Abd-Biab8-D16 or Abd-Biab8-D3. See also Celinker et al. (FBrf0049804).

      (Karch et al., 1990)

      Both m and r function affected to some degree.

      (Kuhn et al., 1993)

      Abd-B m-(+)r- mutation.

      (Kuhn et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      48
      (Kuhn et al., 1995, Kuhn et al., 1993)
      Abd-B.48
      (Kuhn et al., 1993, Karch et al., 1990)
      Abd-B48
      (Estrada et al., 2002)
      Abd-Biab9-48
      iab-748
      (Sanchez-Herrero and Crosby, 1988)
      iab948
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0028654
      References (9)