Snap, α-SNAP, dSNAP, soluble NSF attachment protein
Please see the JBrowse view of Dmel\αSnap for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.45
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
2.3, 1.9, 1.5 (northern blot)
There is only one protein coding transcript and one polypeptide associated with this gene
292 (aa)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\αSnap using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
alphaSnap transcripts are detected in RNA from larvae and adults on northern blots. In situ hybridization in embryos shows expression in the CNS.
JBrowse - Visual display of RNA-Seq signals
View Dmel\αSnap in JBrowse
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.
Snap is required for the terminal (post-furrowing) events of cytokinesis.
dsRNA directed against this gene causes defects in cytokinesis when tested in an RNAi screen in S2 cells.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Area matching Drosophila SNAP gene, Acc. No. U09374.
Snap gene has been cloned and the gene product characterised.
The neurosecretory apparatus of the presynaptic nerve terminal contains a core complex of conserved secretory proteins, Snap is a component this complex.
Source for merge of: Snap l(3)77ABc l(3)77ABa
Source for identity of: αSnap Snap
Renamed from 'Snap' to 'αSnap' to better distinguish the alpha-Snap gene (this one) from the two gamma-Snap genes ('γSnap1'/CG3988 and 'γSnap2'/CG6208).
