FlyBase Gene Report: Dmel\Syx16

General Information

Symbol

Dmel\Syx16

Species

D. melanogaster

Name

Syntaxin 16

Annotation Symbol

CG1467

Feature Type

protein_coding_gene

FlyBase ID

FBgn0031106

Gene Model Status

Current

Stock Availability

9 publicly available

Gene Summary

Syntaxin 16 (Syx16) encodes a member of the soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) family. It is localized to late Golgi compartments and is part of a trans-SNARE complex responsible for endosome-to-Golgi/trans Golgi network retrograde transport. [Date last reviewed: 2018-10-04] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Gene Group
Interactive Fly

Also Known As

Syntaxin, dSyx16, dSyntaxin16

Key Links

Genomic Location

Cytogenetic map

19C6-19C6

Sequence location

X:20,392,334..20,393,751 [-]

Recombination map

1-64

RefSeq locus

NC_004354 REGION:20392334..20393751

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (18 terms)

Molecular Function (3 terms)

Terms Based on Experimental Evidence (2 terms)

CV Term

Evidence

References

enables protein binding

inferred from physical interaction with FLYBASE:Vps45; FB:FBgn0261049

(Morrison et al., 2008)

inferred from physical interaction with FLYBASE:car; FB:FBgn0000257,FLYBASE:Vps33B; FB:FBgn0039335

(Akbar et al., 2009)

enables SNAP receptor activity

inferred from physical interaction with FLYBASE:αSnap; FB:FBgn0250791

(Xu et al., 2002)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

enables SNAP receptor activity

inferred from sequence or structural similarity

(Littleton, 2000)

inferred from biological aspect of ancestor with PANTHER:PTN000461349

(GO Reference Genome Project, 2011-)

non-traceable author statement

(Littleton et al., 1999)

inferred from electronic annotation with InterPro:IPR006012

(InterPro Project Members, 2004-)

enables SNARE binding

inferred from biological aspect of ancestor with PANTHER:PTN000461349

(GO Reference Genome Project, 2011-)

Biological Process (7 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

involved_in Golgi vesicle transport

inferred from mutant phenotype

(Xu et al., 2002)

Terms Based on Predictions or Assertions (6 terms)

CV Term

Evidence

References

involved_in intracellular protein transport

inferred from electronic annotation with InterPro:IPR006012

(InterPro Project Members, 2004-)

inferred from biological aspect of ancestor with PANTHER:PTN000461349

(GO Reference Genome Project, 2011-)

involved_in neurotransmitter secretion

non-traceable author statement

(Lloyd et al., 2000)

involved_in synaptic vesicle docking

inferred from sequence or structural similarity

(Littleton, 2000)

involved_in vesicle docking

inferred from biological aspect of ancestor with PANTHER:PTN000461349

(GO Reference Genome Project, 2011-)

involved_in vesicle fusion

inferred from biological aspect of ancestor with PANTHER:PTN000461349

(GO Reference Genome Project, 2011-)

involved_in vesicle-mediated transport

inferred from electronic annotation with InterPro:IPR010989

(InterPro Project Members, 2004-)

non-traceable author statement

(Lloyd et al., 2000)

Cellular Component (8 terms)

Terms Based on Experimental Evidence (4 terms)

CV Term

Evidence

References

located_in Golgi apparatus

inferred from direct assay

(Akbar et al., 2009, Xu et al., 2002)

located_in Golgi trans cisterna

inferred from direct assay

(Tong et al., 2011)

located_in lysosome

inferred from direct assay

(Akbar et al., 2009)

located_in membrane

inferred from direct assay

(Xu et al., 2002)

Terms Based on Predictions or Assertions (5 terms)

CV Term

Evidence

References

is_active_in endomembrane system

inferred from biological aspect of ancestor with PANTHER:PTN000461349

(GO Reference Genome Project, 2011-)

located_in Golgi membrane

inferred by curator from GO:0005794,GO:0016020

(Xu et al., 2002)

located_in membrane

inferred from electronic annotation with InterPro:IPR006012, InterPro:IPR010989

(InterPro Project Members, 2004-)

located_in plasma membrane

inferred from sequence or structural similarity

(Littleton, 2000)

non-traceable author statement

(Littleton et al., 1999)

part_of SNARE complex

inferred by curator from GO:0005484

(Xu et al., 2002)

inferred from biological aspect of ancestor with PANTHER:PTN000461349

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

Qa-SNAREs

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

Gene Group (FlyBase)

Qa-SNAREs -: Q-SNAREs are members of the SNARE (soluble N-ethylmaleimide-sensitive factor-attachment protein (SNAP) receptor) family that mediate vesicle-fusion. SNAREs are cytoplasmic, membrane-anchored proteins that contain a 60 amino acid SNARE domain. Three Q-SNAREs domains from the target membrane and one R-SNARE domain from the vesicle interact to form a four four-helix bundle that pulls the two membranes in close proximity and promotes fusion. After fusion, the complexes are dissembled by NSF (N-ethylmaleimide-sensitive factor) and SNAPs (Soluble NSF Attachment Proteins). Q-SNAREs are named from their contribution of a conserved glutamine (Q) residue to the helix bundle. Q-SNARE domains are designated a, b or c, depending on their position within the helix bundle. (Adapted from PMID:15893389 and FBrf0216182).

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\Syx16 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VR90)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.50

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

Syx16-RA

FBtr0077330

NM_078696

1282

352

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

Syx16-PA

FBpp0077022

40.4

352

5.19

Q9VR90

NP_523420

AAF50914

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Syx16 using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Syx16_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

4.39

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

S2 cell-line

• Golgi trans cisterna

(Tong et al., 2011)

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

adult head

• membrane

(Aradska et al., 2015)

Additional Descriptive Data

Syx16 protein labels the Golgi trans cisterna in S2 cells.

(Tong et al., 2011)

Marker for

Golgi trans cisterna

(Tong et al., 2011)

Subcellular Localization

CV Term

Evidence

References

located_in Golgi apparatus

inferred from direct assay

(Akbar et al., 2009, Xu et al., 2002)

located_in Golgi trans cisterna

inferred from direct assay

(Tong et al., 2011)

located_in lysosome

inferred from direct assay

(Akbar et al., 2009)

located_in membrane

inferred from direct assay

(Xu et al., 2002)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\Syx16 in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\Syx16

View exonic expression by tissue for Dmel\Syx16

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

33034/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0031106

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0031106

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0031106

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG1467

Flygut - An atlas of the Drosophila adult midgut

FBgn0031106

Images

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 3 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 8 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Syx16

Transgenic constructs containing regulatory region of Syx16

Aberrations (Deficiencies and Duplications) ( 1 )

Inferred from experimentation ( 1 )

Gene disrupted in

Df(1)Exel6254

(Ryder, 2004.4.26)

Inferred from location ( 0 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

partially lethal, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

Syx16^GD3694

viable, with Scer\GAL4^Mef2.PR

Syx16^GD3694

viable, with Scer\GAL4^pnr-MD237

Syx16^GD3694

viable, with Scer\GAL4^tin.CΔ4

Syx16^GD3694

Other Phenotypes

Allele

short lived | heat sensitive, with Scer\GAL4^tin.CΔ4

Syx16^GD3694

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (16)

Hsap\STX16

14 of 14

Yes

Hsap\STX7

2 of 14

Hsap\STX12

2 of 14

Hsap\STX16-NPEPL1

2 of 14

Yes

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (13)

Rnor\Stx16

14 of 14

Yes

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Mus musculus (laboratory mouse) (12)

Mmus\Stx16

13 of 14

Yes

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (9)

Xtro\stx16

8 of 13

Yes

Xtro\dcun1d2

1 of 13

Yes

Xtro\mpzl3

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Danio rerio (Zebrafish) (20)

Drer\stx16

13 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (10)

Cele\syx-16

14 of 14

Yes

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Anopheles gambiae (African malaria mosquito) (9)

Agam\AgaP_AGAP000850

12 of 12

Yes

2 of 12

2 of 12

2 of 12

1 of 12

1 of 12

1 of 12

1 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (24)

Atha\SYP41

12 of 13

Yes

Atha\SYP42

12 of 13

Yes

Atha\SYP43

12 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Saccharomyces cerevisiae (Brewer's yeast) (6)

Scer\TLG2

12 of 13

Yes

3 of 13

2 of 13

1 of 13

1 of 13

1 of 13

Schizosaccharomyces pombe (Fission yeast) (4)

Spom\tlg2

12 of 12

Yes

Spom\pep12

2 of 12

Spom\psy1

1 of 12

Spom\sed5

1 of 12

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:Syx16. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (7)

4 of 13

4 of 13

4 of 13

3 of 13

3 of 13

3 of 13

1 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 1 )

Human Ortholog

Disease

Evidence

References

STX16; syntaxin 16

model of pseudohypoparathyroidism type IB

IEA

(FlyBase, 2019-)

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

STX16; syntaxin 16

14 of 14

603666

PSEUDOHYPOPARATHYROIDISM, TYPE IB; PHP1B

pseudohypoparathyroidism type IB

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Show neighbor-neighbor interactions:

Off

Show/hide secondary interactors
(data from AllianceMine provided by esyN)

Select Layout:

Force Directed

Circle

Concentric

Legend:

Protein

RNA

Selected Interactor(s)

Other Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

Syx16 - AttD

experimental knowledge based

(Guruharsha et al., 2011)

Syx16 - Membrin

experimental knowledge based

(Guruharsha et al., 2011)

Syx16 - Sec22

experimental knowledge based

(Guruharsha et al., 2011)

Syx16 - Slh

experimental knowledge based

(Guruharsha et al., 2011)

Syx16 - Snap24

experimental knowledge based

(Guruharsha et al., 2011)

Syx16 - Snap25

experimental knowledge based

(Guruharsha et al., 2011)

Syx16 - Snap29

anti bait coimmunoprecipitation, western blot, pull down, experimental knowledge based

(Xu et al., 2014, Guruharsha et al., 2011)

Syx16 - Syb

experimental knowledge based

(Guruharsha et al., 2011)

Syx16 - Syx13

experimental knowledge based

(Guruharsha et al., 2011)

Syx16 - Syx1A

experimental knowledge based

(Guruharsha et al., 2011)

Syx16 - Syx4

experimental knowledge based

(Guruharsha et al., 2011)

Syx16 - Syx5

experimental knowledge based

(Guruharsha et al., 2011)

Syx16 - Syx7

experimental knowledge based

(Guruharsha et al., 2011)

Syx16 - Syx8

experimental knowledge based

(Guruharsha et al., 2011)

Syx16 - Vamp7

experimental knowledge based

(Guruharsha et al., 2011)

Syx16 - Vps33B

anti bait coimmunoprecipitation, anti tag western blot

(Akbar et al., 2009)

Syx16 - Vps45

pull down, anti tag western blot

(Morrison et al., 2008)

Syx16 - Vti1a

experimental knowledge based

(Guruharsha et al., 2011)

Syx16 - car

anti bait coimmunoprecipitation, anti tag western blot

(Akbar et al., 2009)

Syx16 - koko

experimental knowledge based

(Guruharsha et al., 2011)

Syx16 - αSnap

pull down, western blot, two hybrid, experimental knowledge based

(Guruharsha et al., 2011, Xu et al., 2002)

Syx16 - γSnap1

experimental knowledge based

(Guruharsha et al., 2011)

Summary of Genetic Interactions

esyN Network Diagram

Show/hide secondary interactors
(data from AllianceMine provided by esyN)

esyN Network Key:

Suppression

Enhancement

Other Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Nsf2

enhanceable

Syx16

(Xu et al., 2002)

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

59325

DroID - A comprehensive database of gene and protein interactions.

FBgn0031106

MIST (protein-protein) - An integrated Molecular Interaction Database

33034

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

External Data

Linkouts

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

SNARE interactions in vesicular transport

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

1-64

Cytogenetic map

19C6-19C6

Sequence location

X:20,392,334..20,393,751 [-]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

19C6-19C6

Limits computationally determined from genome sequence between P{EP}amn^EP1639&P{EP}amn^EP367 and P{EP}CG1702^EP1525

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

19C-19E

(Cordes, 1999.9.22)

Experimentally Determined Recombination Data

Location

1-64

(FlyBase, 2016)

1-64.3

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (9)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

25884

y¹ v¹; P{TRiP.JF01924}attP2

51856

y¹ v¹; P{TRiP.HMC03430}attP40

13136

y¹ w^67c23 P{Mae-UAS.6.11}Syx16^GG01176

78180

y¹ sc^* v¹ sev²¹; P{TOE.GS01340}attP40

Korea

10656

P{EP}Syx16^G380

Kyoto

124007

w¹¹¹⁸ P{RS3}Syx16^CB-6266-3

NIG-Fly

HMJ22340

y¹ v¹; P{TRiP.HMJ22340}attP40/CyO

VDRC

v109504

P{KK108039}VIE-260B

v8644

w¹¹¹⁸; P{GD3694}v8644

Genomic Clones (14)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (12)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

GH10149

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0031106

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0031106

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R⁺ cell morphology.

(Kiger et al., 2003)

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Source for identity of: Syx16 CG1467

(Verstreken and Bellen, 2000.9.4)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (15)

Reported As

Symbol Synonym

CG1467

(National Institute of Genetics Fly Stocks, 2023-, Ni et al., 2010.12.1, Keleman et al., 2009.8.5, Perkins et al., 2009.1.15, Gandhi et al., 2007, Bock, 2000.10.26)

Dm Syx16

(Littleton, 2000)

DmSyx16

(McLennan, 2001.5.22)

SYX16

(Tong et al., 2011, Lloyd et al., 2000)

Syx

(Wagh et al., 2006)

Syx16

(Bourne et al., 2022, Transgenic RNAi Project members, 2017-, Borner et al., 2014, Charng et al., 2014, Reinhardt and Jones, 2013, Takáts et al., 2013, Yamamoto-Hino et al., 2012, Williamson et al., 2010, Kloepper et al., 2008, Morrison et al., 2008, Lagow et al., 2007, Bandyopadhyay et al., 2006)

dStx16

(Patel et al., 2020)

dSyx 16

(Shimada et al., 2006)

dSyx16

(Xu et al., 2014, Tong et al., 2011, Zhang and Ten Hagen, 2010, Xu et al., 2002)

Name Synonyms

Syntaxin

(Hossain et al., 2008, Kittel et al., 2006, Pereanu and Hartenstein, 2006, Wagh et al., 2006)

Syntaxin 16

(Saadin and Starz-Gaiano, 2018, Belloni et al., 2012, Giagtzoglou et al., 2012, McLennan, 2001.5.22)

Syntaxin16

(Yamamoto-Hino et al., 2012, Tiklová et al., 2010)

dSyntaxin16

(Tong et al., 2011, Akbar et al., 2009)

syntaxin

(Dumstrei et al., 2003)

syntaxin 16

(Leventis et al., 2011, Tiklova et al., 2010)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 40 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

33034

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VR90

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VR90

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

33034/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0031106

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0031106

FlyMine - An integrated database for Drosophila genomics

FBgn0031106

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG1467

MARRVEL_MODEL - MARRVEL (model organism gene)

33034

Linkouts

BioGRID - A database of protein and genetic interactions.

59325

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0031106

DroID - A comprehensive database of gene and protein interactions.

FBgn0031106

DRSC - Results frm RNAi screens

FBgn0031106

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

Syx16_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0031106

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0031106

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG1467

Flygut - An atlas of the Drosophila adult midgut

FBgn0031106

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0031106

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC009870

KEGG Pathways - A collection of manually drawn pathway maps representing knowledge of molecular interaction, reaction and relation networks.

SNARE interactions in vesicular transport

MIST (protein-protein) - An integrated Molecular Interaction Database

33034

Reactome - An open-source, open access, manually curated and peer-reviewed pathway database.

References (77)

The following external sites may use different assemblies or annotations than FlyBase.

4.39

Report Sections