Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\gfr using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\gfr in JBrowseThe gfr complementation group maps to the 70A-70B chromosomal region, 0.39cM from P{SUPor-P}tRNA:CR32123:ΨKG01069 and 0.82cM from P{GT1}BG00690.
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
"gfr" mutant alleles do not behave as simple loss-of-function mutations: they are lethal in trans to each other, yet completely viable and without obvious phenotypes in trans to all available deficiencies and lethal lesions mapping to the 70A-70B chromosomal region (to which the "gfr" complementation group maps). Instead, evidence suggests that "gfr" alleles behave as gain-of-function lesions and that overexpression of "bru-3" is central to the "gfr" mutant phenotype.