Please see the JBrowse view of Dmel\Bulli for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.46
There is only one protein coding transcript and one polypeptide associated with this gene
Component of the Mon1-Ccz1 guanyl-nucleotide exchange factor complex made up of Mon1, Ccz1 and Bulli; the interaction of Bulli with the Mon1-Ccz1 heterodimer is mediated via the C-terminal Mic1 domain of Bulli (PubMed:32499409, PubMed:37155863). Mon1 and Ccz1 form a stable complex which displays Rab7 GEF activity with or without Bulli; GEF activity is enhanced by Bulli possibly by improving membrane association of the complex (PubMed:32499409, PubMed:37155863).
The C-terminal Mic1 domain consists of an alpha-solenoid structure that acts as a protein interaction scaffold for the CCZ1-MON1 complex.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Bulli using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\Bulli in JBrowse3-17
3-14.8
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Bulli CG8270
Named 'Bulli' after the nickname of a classical German bus from the 1970s that facilitated cargo trafficking.