An 8bp deletion causing a frame-shift and premature stop codon after 389 amino acids, therefore lacking the C-terminal half of the protein, which includes the complete alpha-solenoid region of the protein.
An 8bp deletion beginning in codon 391 that causes a frameshift and leads to early translation termination.
Bulli6-61 homozygous or Bulli6-61/Bullif03412 nephrocyte cells exhibit a high number of endosomes (some of them are not acidified) with a significantly enlarged diameter in third instar larvae. Also the labyrinth channel system of Bulli6-61 homozygous endosomes is slightly enlarged, disorganized, and extended throughout the entire cell.