Sr, Star/asteroid
Please see the JBrowse view of Dmel\ast for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.45
2.9 (northern blot)
There is only one protein coding transcript and one polypeptide associated with this gene
815 (aa); 93.5 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ast using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: rapidly degraded
ast transcript expression is high during embryonic and pupal stages. In the embryo, expression is restricted to proliferating tissues.
JBrowse - Visual display of RNA-Seq signals
View Dmel\ast in JBrowse2-1.5
2-1.4
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Mutations in ast cause pleiotropic phenotypes in embryonic patterns and affect several longitudinal veins.
Mutants show a small rough eye phenotype with the longitudinal wing veins failing to meet the wing margin. Interact with alleles of S.
Shs.8 (FBrf0073598) rescues the embryonic lethality of S104E and S1, and the rough eye phenotype of ast, even in the absence of heat shock. On the basis of this rescue, ast and S merged to same gene. Split again on the basis of new molecular data (FBrf0085372).
Source for identity of: ast CG4426