pasc, wap, l(1)C204, EG:87B1.2 , N2
Please see the JBrowse view of Dmel\wapl for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.53
6.5 (northern blot)
6.3 (northern blot)
1741 (aa); 200 (kD predicted)
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\wapl using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\wapl in JBrowsePlease Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
polyclonal
wapl controls heterochromatin organisation.
Mutations in wapl prevent the normal close apposition of sister chromatids in heterochromatic regions, but do not appear to affect either heterochromatin condensation or chromosome segregation.
In(1LR)pn2a strongly inactivates wapl in females.
Synonym "l(1)2Dd" on p777 and "l(1)2Df" on p311.
A saturation analysis of the 2D3--2F5 region detected the wapl complementation group.
Most alleles are lethal. Semilethal escapers show wings-apart phenotype.