FlyBase Aberration Report: Dmel\T(2;3)Sb[V]

General Information

Symbol

T(2;3)Sb^V

Species

D. melanogaster

Name

Translocation (2;3) Stubble-Variegated

FlyBase ID

FBab0007740

Feature type

inversion_cum_translocation

Also Known As

Sb^V

Computed Breakpoints include

88;89B9;41A-41C

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

In(3R)Mo

Mutagen

X ray

Class of aberration (relative to wild type)

inversion_cum_translocation

(FlyBase, 2007)

Class of aberration (relative to progenitor)

inversion_cum_translocation

chromosomal_translocation

(Heitzler et al., 1996)

Breakpoints

[];89B9;41A--C

(Heitzler et al., 1996)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

bk2 hits Sb

Genetic mapping information

Comments

Comments on Cytology

Limits of break 1 from polytene analysis (citation unavailable) Limits of break 2 from polytene analysis (FBrf0088194) Limits of break 3 from polytene analysis (FBrf0088194)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

(Heitzler et al., 1996)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location

Related Comments

Phenotypic Data

In combination with other aberrations

Df(1)109 does not dominantly affect position effect variegation at the Sb locus which is caused by T(2;3)Sb^V.

(Sakaguchi et al., 2008)

Df(1)174 does not dominantly affect position effect variegation at the Sb locus which is caused by T(2;3)Sb^V.

(Sakaguchi et al., 2008)

Position effect variegation (PEV) at the Sb locus caused by T(2;3)Sb^V is dominantly enhanced by Dp(2;2)Mdh, and suppressed by Df(2R)en-A or Df(2R)en-SFX31.

(Sinclair et al., 1998)

The position effect variegation of Sb caused by T(2;3)Sb^V is strongly suppressed by C(1;YL)w^mMc in both males and females. This interaction is both dominant and dosage sensitive; one copy of the C(1;YL)w^mMc chromosome is sufficient to suppress variegation of Sb caused by T(2;3)Sb^V, however, two copies of C(1;YL)w^mMc produce slightly greater suppression than one copy. The In(1)w^m51b and In(1)w^m4 chromosomes have similar, although less dramatic, suppressing effects on Sb variegation caused by T(2;3)Sb^V. T(1;4)w^mJ has no clear effect on the variegation of Sb caused by T(2;3)Sb^V. The T(2;3)Sb^V chromosome may have a slight suppressing effect on the variegation of w caused by C(1;YL)w^mMc and In(1)w^m4 in males, but has no clear effect on the variegation of w caused by In(1)w^m51b or T(1;4)w^mJ.

(Lloyd et al., 1997)

NOT in combination with other aberrations

Flies carrying one copy of T(2;3)Sb^V frequently display a mosaic thoracic bristle phenotype, wherein bristles are both short and long; this phenotype that is enhanced by one copy of Su(var)205⁴ or Su(var)3-9⁶, but unaffected by one copy of HIPP1^1G3, HIPP1^3G10, HIPP1^Δ37, HIPP1^ΔDsR, HIPP1^sfGFP.

(Glenn and Geyer, 2019)

Mutations of Rm62 increase the number of mutant bristles.

(Csink et al., 1994)

Position-effect variegation and effect of variegation modifiers on expression of Sb in T(2;3)Sb^V studied.

(Bishop, 1992)

Sb^V/+ has mixture of wild-type and Sb bristles. In X/X/Y female and X/Y/Y male, bristles nearly all Sb. In X/0 male, bristles usually all wild type. Sb^V/Sb and homozygous Sb^V are lethal. RK1A. weak allele homozygous lethal

Stocks (1)

Bloomington

878

T(2;3)Sb^V, In(3R)Mo, Sb¹ sr¹/TM3, Ser¹

Notes on Origin

Discoverer

E.B. Lewis, 1948.

carrying Sb sr Induced with, but genetically separable from In(3LR)P35.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

Sb^V

(Mills et al., 2018, Shalaby et al., 2017, Hong and Choi, 2016, Malmanche and Clark, 2003, Sinclair et al., 1998, Lloyd et al., 1997, Appel, 1995, Csink et al., 1994, Sinclair et al., 1992)

Sb^v

(Gandhi et al., 2015)

T(2;3)Sb-V

T(2;3)Sb^V

(Glenn and Geyer, 2019, Lee et al., 2018, Roelens et al., 2017, Neguembor et al., 2013, Gurudatta et al., 2010, Fagegaltier et al., 2009, Lu et al., 2009, Weiler and Chatterjee, 2009, Sasai et al., 2007, Weiler, 2007)

T(2;3)Sb^v

(Di Stefano et al., 2011, Sakaguchi et al., 2008, Di Stefano et al., 2007, Greil et al., 2007, Rudolph et al., 2007, Song et al., 2007)

Name Synonyms

Translocation (2;3) Stubble-Variegated

Secondary FlyBase IDs

FBal0015149

References (42)

Report Sections

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