Insertion within the coding sequence.
Rab19LL00490/Df(3L)BSC815 transheterozygotes show a significant increase in the number of Prospero-positive precursor/mature enteroendocrine cells in the adult gut, as compared to controls. These mutants also show a severe decrease in lifespan upon oral infection with Enterococcus faecalis.
Rab19LL00490, Scer\GAL4pros-V1 has increased cell number | adult stage phenotype, suppressible by sliEY10695, Scer\GAL4pros-V1
Atg16d129, Rab19[+]/Rab19LL00490 has increased cell number | adult stage phenotype
Rab19LL00490, Scer\GAL4pros-V1 has adult posterior midgut epithelium phenotype, suppressible by sliEY10695, Scer\GAL4pros-V1
Rab19LL00490, Scer\GAL4pros-V1 has enteroblast | adult stage phenotype, suppressible by sliEY10695, Scer\GAL4pros-V1
Atg16d129, Rab19[+]/Rab19LL00490 has adult posterior midgut epithelium phenotype
Atg16d129, Rab19[+]/Rab19LL00490 has enteroblast | adult stage phenotype
Atg16d129, Rab19[+]/Rab19LL00490 has enteroendocrine cell | adult stage phenotype
Atg16d129, Rab19LL00490 double heterozygotes exhibit a significant increase in the number of Prospero-positive precursor/mature enteroendocrine cells in the adult gut, as compared to the single heterozygotes or wild-type controls.
The increased number of pre-enteroendocrine cells in the adult gut of Rab19LL00490/Df(3L)BSC815 transheterozygotes is suppressed by the co-expression of sliEY10695 under the control of Scer\GAL4pros-V1.