FlyBase Allele Report: Dmel\Rala[35d]

General Information

Symbol

Dmel\Rala^35d

Species

D. melanogaster

Name

FlyBase ID

FBal0280553

Feature type

allele

Associated gene

Dmel\Rala

Associated Insertion(s)

P{?GawB}Rala^35d

Carried in Construct

Key Links

Allele class

hypomorphic allele - molecular evidence

Mutagen

P-element activity

Nature of the Allele

Allele class

hypomorphic allele - molecular evidence

(Balakireva et al., 2006)

Mutagen

P-element activity

(Balakireva et al., 2006)

Progenitor genotype

P{GawB}Rala^PG89

(Balakireva et al., 2006)

Associated Insertion(s)

P{?GawB}Rala^35d

Cytology

Description

Imprecise excision of the progenitor insertion, in which most of the original element has been excised, but both P-element terminal repeats remain.

(Balakireva et al., 2006)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable

(Balakireva et al., 2006)

visible | recessive

(Balakireva et al., 2006)

Phenotype Manifest In

macrochaeta

(Balakireva et al., 2006)

microchaeta

(Balakireva et al., 2006)

trichogen cell

(Balakireva et al., 2006)

Detailed Description

Statement

Reference

Adult hemizygous males show a loss of bristle phenotype: the external parts of the sensory organs consist of an empty socket with no shaft. This phenotype is seen for both microchaetae and macrochaetae. Apoptosis of a single cell occurs in many developing macrochaetae during the pupal stage in the mutant animals. This cell death occurs after the appropriate cell divisions have taken place in the bristle lineage, and the dying cell appears to be a descendent of the pIIa cell that gives rise to the shaft and socket cells.

(Balakireva et al., 2006)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Rala^35d has visible phenotype, enhanceable by msn^EP549/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has visible phenotype, enhanceable by msn^{Δ332-667.UAS}/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has visible phenotype, enhanceable by Traf4^EP578/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has visible phenotype, enhanceable by Rlip^UAS.WT/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has visible phenotype, enhanceable by Df(3R)crb-F89-4/+

(Balakireva et al., 2006)

Rala^35d has visible phenotype, enhanceable by Mekk1^Ur36/Mekk1[+]

(Balakireva et al., 2006)

Rala^35d has visible phenotype, enhanceable by Sec5^E10/sec5[+]

(Balakireva et al., 2006)

Rala^35d has visible phenotype, enhanceable by sec15[+]/Sec15^GE24290

(Balakireva et al., 2006)

Rala^35d has visible phenotype, enhanceable by puc^E69/puc[+]

(Balakireva et al., 2006)

Rala^35d has visible phenotype, enhanceable by Exo70^GE23538/exo70[+]

(Balakireva et al., 2006)

Rala^35d has visible phenotype, enhanceable by Scer\GAL4^sca-537.4/msn^UAS.cSa

(Balakireva et al., 2006)

NOT Enhanced by

Statement

Reference

Rala^35d has visible phenotype, non-enhanceable by Scer\GAL4^sca-537.4/BacA\p35^UAS.cHa

(Balakireva et al., 2006)

Rala^35d has visible phenotype, non-enhanceable by msn^D160N.UAS/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Suppressed by

Statement

Reference

Rala^35d has visible phenotype, suppressible by kay^DN.UAS/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has visible phenotype, suppressible | partially by Rlip[+]/Rlip^GE28345

(Balakireva et al., 2006)

Rala^35d has visible phenotype, suppressible | partially by bsk¹/bsk[+]

(Balakireva et al., 2006)

Rala^35d has visible phenotype, suppressible | partially by bsk²/bsk[+]

(Balakireva et al., 2006)

Rala^35d has visible phenotype, suppressible | partially by msn[+]/msn¹⁰²

(Balakireva et al., 2006)

Rala^35d has visible phenotype, suppressible | partially by msn¹⁷²/msn[+]

(Balakireva et al., 2006)

Rala^35d has visible phenotype, suppressible by Jra^DN.UAS/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has visible phenotype, suppressible | partially by Scer\GAL4^sca-537.4/Dronc^CARD.UAS

(Balakireva et al., 2006)

NOT suppressed by

Statement

Reference

Rala^35d has visible phenotype, non-suppressible by msn^D160N.UAS/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has visible phenotype, non-suppressible by Scer\GAL4^sca-537.4/BacA\p35^UAS.cHa

(Balakireva et al., 2006)

Phenotype Manifest In

Enhanced by

Statement

Reference

Rala^35d has microchaeta phenotype, enhanceable by Rlip^UAS.WT/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, enhanceable by Rlip^UAS.WT/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, enhanceable by msn^EP549/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, enhanceable by msn^{Δ332-667.UAS}/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, enhanceable by msn^{Δ332-667.UAS}/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, enhanceable by Traf4^EP578/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, enhanceable by Traf4^EP578/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, enhanceable by Df(3R)crb-F89-4/+

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, enhanceable by Df(3R)crb-F89-4/+

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, enhanceable by Mekk1^Ur36/Mekk1[+]

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, enhanceable by Mekk1^Ur36/Mekk1[+]

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, enhanceable by Sec5^E10/sec5[+]

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, enhanceable by Sec5^E10/sec5[+]

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, enhanceable by sec15[+]/Sec15^GE24290

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, enhanceable by sec15[+]/Sec15^GE24290

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, enhanceable by puc^E69/puc[+]

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, enhanceable by puc^E69/puc[+]

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, enhanceable by Exo70^GE23538/exo70[+]

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, enhanceable by Exo70^GE23538/exo70[+]

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, enhanceable by Scer\GAL4^sca-537.4/msn^UAS.cSa

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, enhanceable by Scer\GAL4^sca-537.4/msn^UAS.cSa

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, enhanceable by msn^EP549/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

NOT Enhanced by

Statement

Reference

Rala^35d has microchaeta phenotype, non-enhanceable by msn^D160N.UAS/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, non-enhanceable by Scer\GAL4^sca-537.4/BacA\p35^UAS.cHa

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, non-enhanceable by Scer\GAL4^sca-537.4/BacA\p35^UAS.cHa

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, non-enhanceable by msn^D160N.UAS/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Suppressed by

Statement

Reference

Rala^35d has microchaeta phenotype, suppressible | partially by msn¹⁷²/msn[+]

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, suppressible by msn¹⁷²/msn[+]

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, suppressible | partially by bsk¹/bsk[+]

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, suppressible by bsk¹/bsk[+]

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, suppressible | partially by bsk²/bsk[+]

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, suppressible by bsk²/bsk[+]

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, suppressible by Jra^DN.UAS/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, suppressible by Jra^DN.UAS/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, suppressible by kay^DN.UAS/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, suppressible by kay^DN.UAS/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, suppressible | partially by Rlip[+]/Rlip^GE28345

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, suppressible by Rlip[+]/Rlip^GE28345

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, suppressible | partially by Scer\GAL4^sca-537.4/Dronc^CARD.UAS

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, suppressible by Scer\GAL4^sca-537.4/Dronc^CARD.UAS

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, suppressible | partially by msn[+]/msn¹⁰²

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, suppressible by msn[+]/msn¹⁰²

(Balakireva et al., 2006)

NOT suppressed by

Statement

Reference

Rala^35d has microchaeta phenotype, non-suppressible by msn^D160N.UAS/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, non-suppressible by msn^D160N.UAS/Scer\GAL4^sca-537.4

(Balakireva et al., 2006)

Rala^35d has microchaeta phenotype, non-suppressible by Scer\GAL4^sca-537.4/BacA\p35^UAS.cHa

(Balakireva et al., 2006)

Rala^35d has macrochaeta phenotype, non-suppressible by Scer\GAL4^sca-537.4/BacA\p35^UAS.cHa

(Balakireva et al., 2006)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Ral^35d

(Balakireva et al., 2006)

Rala^35d

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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